5 4 4 5 5 Tetramethyl 1 3 2 Dioxaborolan 2 Yl Pyridine 2 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbonitrile

    Specifications

    HS Code

    118573

    Chemical Formula C15H19BN2O2
    Molecular Weight 270.135
    Appearance Solid (likely white or off - white)
    Physical State At Room Temp Solid
    Solubility In Common Solvents Soluble in organic solvents like dichloromethane, chloroform

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    General Information
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    Frequently Asked Questions

    As a leading 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronitrile) pyridine-2-formonitrile
    The main use of 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentaborane-2-yl) for its-2-methylbenzene is as an important intermediate in organic synthesis.
    In the field of organic synthesis, such compounds play a key role. On the one hand, it can participate in carbon-carbon bond formation reactions such as the Suzuki-Miyaura coupling reaction. In such reactions, the boron group in the compound can efficiently construct new carbon-carbon bonds with halogenated aromatics or halogenated olefins under the action of suitable catalysts (such as palladium catalysts) and bases, which is crucial for the synthesis of complex organic molecules with specific structures. It is widely used in pharmaceutical chemistry, materials science and other fields. For example, in the development of new drugs, different structural fragments can be connected through this reaction to construct a library of compounds with potential biological activities.
    On the other hand, it can be used to introduce specific functional groups or structural units. Due to its unique structure, it is possible to precisely locate and modify target molecules in reactions, providing an effective way for the synthesis of organic compounds with special functions or structures. In terms of material synthesis, organic materials with specific photoelectric properties can be prepared by means of the reactions they participate in, which can be used in the fields of organic Light Emitting Diodes (OLEDs), solar cells, etc.
    In summary, 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentaborane-2-yl) has an indispensable use for its-2-methylbenzene in many important fields of organic synthesis, which has greatly promoted the development and progress of related science and technology.
    What are the synthesis methods of 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronitrile) pyridine-2-formonitrile
    To prepare\ (5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentaborane-2-yl) -2-methylpyridine, the synthesis method is as follows:
    You can first use\ (2-methylpyridine as the starting material, and introduce a suitable functional group at the\ (5\) position of the pyridine ring through a suitable electrophilic substitution reaction. This functional group can be subsequently converted into a group capable of reacting with\ (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentaborane\).
    For example, a halogenating agent, such as bromine or chlorine, can be used first to make\ (2-methylpyridine\) undergo a\ (5-methylpyridine\) halogenation reaction under appropriate reaction conditions to generate\ (5-halogenated-2-methylpyridine\). Thereafter, the\ (5 -halo-2 -methylpyridine\) with\ (4,4,5,5 -tetramethyl-1,3,2 -dioxaboron heterocyclopentaborane\) in a palladium catalyst, such as tetrakis (triphenylphosphine) palladium\ ([Pd (PPh_ {3}) _ {4}]\) catalyzed by Suzuki (Suzuki) coupling reaction occurs in an alkaline environment. The basic reagent can be selected from potassium carbonate\ ((K_ {2} CO_ {3}) \), sodium carbonate\ ((Na_ {2} CO_ {3}) \), etc., in a suitable organic solvent, such as a mixed solvent of dioxane and water, etc. The reaction is carried out to obtain the target product\ (5- (4,4,5,5-tetramethyl-1,3,2-dioxaborane-2-yl) -2-methylpyridine\).
    Another idea is to use the boric acid ester containing the pyridine structure as the raw material, first functionalize the ortho-site of the methyl group on the pyridine ring, introduce the ability to react with\ (4,4,5,5 -tetramethyl-1,3,2 -dioxaboronacyclopentaborane\) activity check point, and then through the reaction with\ (4,4,5,5 -tetramethyl-1,3,2 -dioxaboronacyclopentaborane\) under suitable reaction conditions to construct the structure of the target product. The specific reaction conditions need to be optimized according to the selected raw materials and reaction paths to improve the reaction yield and selectivity.
    What are the physical properties of 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronitrile) pyridine-2-formonitrile
    5- (4,4,5,5-tetramethyl-1,3,2-dioxane-2-yl) to its-2-ethylpyridine is an organic compound. The following describes its physical properties for you:
    This compound is a colorless to light yellow liquid at room temperature and pressure, with certain fluidity and no special solid shape. Due to the presence of specific groups, there are various interactions between molecules, which give it a unique boiling point and melting point. In terms of boiling point, or within a certain range, due to the influence of carbon chains and heterocycles in the molecular structure, the intermolecular force is moderate, and a certain amount of energy is required to overcome the force to transform the liquid phase into the gas phase. The specific boiling point value depends on the precise chemical structure and purity. In terms of melting point, or a specific temperature, at this temperature, molecules transition from an ordered solid lattice arrangement to a disordered liquid state.
    This substance has unique solubility. In common organic solvents such as ethanol and dichloromethane, it can be dissolved by the interaction between molecules and solvent molecules due to the principle of similar miscibility. In water, due to the large difference in molecular polarity from water and the presence of hydrophobic alkyl groups, its solubility in water is poor.
    In terms of density, due to the fixed type and quantity of atoms composed of molecules, the mass per unit volume is relatively stable, and the density may be close to a certain value. Compared with the density of water, it may be greater or less than that of water, depending on the degree of compactness of the molecular structure and the sum of the atomic mass.
    In addition, the compound may have a specific odor. The odor originates from the vibration and interaction of atoms in the molecular structure, which produces odor perception when interacting with nasal olfactory receptors. The specific odor may vary depending on the specific functional groups contained in the structure, such as the pyridine ring, which may give it a special pungent odor.
    What should be paid attention to when storing 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronitrile) pyridine-2-formonitrile?
    Fu 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentaborane-2-yl) alkynyl-2-methylpyridine When storing, pay attention to many matters.
    This compound contains a special boron heterocyclic structure, which may be more active. First, pay attention to the temperature and humidity of the storage environment. Due to high humidity, water molecules may interact with boron-containing structures and cause the compound to deteriorate, so it should be stored in a dry place. A desiccant can be placed next to the storage container to keep the environment dry. Temperature is also critical. Excessive temperature may cause the compound to decompose or accelerate its reaction with substances in the environment. It is best to store it in a low temperature and constant temperature place, such as a refrigerated environment, but be careful not to freeze it and cause the container to break.
    Second, this compound contains alkynyl and pyridyl groups, and has high chemical activity. When storing, avoid contact with oxidants, strong acids, strong bases and other substances. Oxidation reactions occur in oxidants or alkynyl groups, destroying the molecular structure; strong acids and strong bases may also react with pyridyl groups or other parts to change the properties of the compound. Storage containers should be made of chemically stable materials that do not react with them, such as specific glass materials or inert plastic materials.
    Furthermore, this compound has a certain volatility or odor, and the storage place should be well ventilated to prevent the accumulation of volatile gases, which not only guarantees the purity of the compound, but also protects the safety of the experimental personnel and prevents health damage caused by inhalation of harmful gases.
    In summary, when storing 5- (4,4,5,5-tetramethyl-1,3,2-dioxoboronheterocyclopentaborane-2-yl) alkynyl-2-methylpyridine, use a suitable container in a dry, low temperature, protected from acid-base oxidants and well ventilated place to keep its properties stable for subsequent use.
    What is the market price of 5- (4,4,5,5-tetramethyl-1,3,2-dioxaboronitrile) pyridine-2-formonitrile
    Today there are 5- (4,4,5,5-tetramethyl-1,3,2-dioxacyclopentaborane-2-yl) - 2-methylpyridine, what is the market price of its 2-methylpyridine?
    Prices often vary due to various factors of supply and demand over time and place, and it is difficult to generalize. In today's world, the prices of chemical substances fluctuate frequently. If this 2-methylpyridine is in the ordinary market, its price may vary according to purity and quantity.
    If its purity is very high and it reaches the level of industrial excellence, when the quantity is small, the price per gram may be between a few yuan and tens of yuan. If it is purchased in bulk, and the quantity is measured in kilograms or even tons, the price per gram may be slightly reduced, or to several yuan per gram.
    However, if the supply and demand are uneven at times, the supply is less and the demand is more, the price will rise; if the supply exceeds the demand, the price may be depressed. And in different places, the price is also poor due to transportation, taxes, etc. Or in prosperous commercial ports, the logistics is convenient, and the price may be slightly flat; in remote places, due to difficult transshipment, the price may be high.
    And chemical substances, the price is also affected by the cost of raw materials and production process. If the raw materials are easy to obtain and the process is simple and economical, the price may be close to the people; if the raw materials are rare and the process is complicated, the price will be high. < Br >
    Therefore, in order to determine the market price of 2-methylpyridine, a more accurate figure can be obtained by carefully examining the current supply and demand situation and consulting various chemical companies and market brokers.