4H-imidazo[4,5-b]pyridine

4H-imidazolo [4,5-b] pyridine is an organic compound with a wide range of uses.
In the field of medicine, this compound has significant effects. Many studies are based on it to develop drugs because it has a specific chemical structure and biological activity. For some drug development for neurological diseases, 4H-imidazolo [4,5-b] pyridine can act as a key intermediate, helping to synthesize substances that have a positive impact on neurotransmitter regulation, or can be used to treat neurological diseases such as depression and anxiety. And in the exploration of anticancer drugs, this compound has also attracted attention. After its structure is modified, it may inhibit the growth and proliferation of cancer cells, opening up new paths for the creation of anticancer drugs.
In the field of materials science, 4H-imidazolo [4,5-b] pyridine is also useful. Due to its unique chemical properties, it can be used as a basic unit for the construction of new functional materials. When designing and synthesizing materials with special optical and electrical properties, introducing them into molecular structures may endow materials with unique photoelectric properties, such as in the research and development of organic Light Emitting Diode (OLED) materials to improve the luminous efficiency and stability of materials and enhance the display effect.
In chemical research, it is an important synthetic block. Chemists use it to build more complex organic molecular structures, connect them with other functional groups or molecular fragments through various chemical reactions, expand the diversity of organic synthesis, and provide powerful tools for exploring new chemical substances and reaction paths, promoting the continuous development of organic chemistry.

4H-imidazolo [4,5-b] pyridine is one of the organic compounds. Its physical properties are quite unique, let me explain in detail.
Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This state is easy to identify, and in many chemical reactions and experimental operations, its powder state is more conducive to uniform dispersion, thereby improving the reaction efficiency.
When it comes to melting point, 4H-imidazolo [4,5-b] pyridine usually has a specific numerical range. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The characteristics of its melting point are of great significance in the fields of purity identification, separation and purification of compounds. By accurately measuring the melting point, the purity geometry of the compound can be inferred. If the measured melting point matches the theoretical melting point or the deviation is very small, it is highly likely to indicate that the purity is high; conversely, if the deviation is large, it may contain impurities.
Furthermore, solubility is also one of its important physical properties. Among common organic solvents, such as methanol, ethanol, dichloromethane, etc., 4H-imidazolo [4,5-b] pyridine exhibits different degrees of solubility. In methanol and ethanol, it may have a certain solubility. This property makes it possible to use such solvents as reaction media during organic synthesis to help the reaction proceed smoothly. In water, its solubility is relatively limited, which limits its application in aqueous systems. However, it also provides ideas for its separation and purification. The differential solubility between water and organic solvents can be used to achieve effective separation of the compound.
In addition, the density of 4H-imidazolo [4,5-b] pyridine is also a key physical parameter. The density is also the mass of the substance per unit volume. Knowing its density can accurately control the dosage when it involves quantitative analysis, solution preparation and other operations to ensure the accuracy and reproducibility of the experiment.
In conclusion, the physical properties of 4H-imidazolo [4,5-b] pyridine, such as appearance, melting point, solubility, density, etc., play a decisive role in its application in organic synthesis, drug discovery, materials science, and many other fields. Researchers need to explore in detail to make good use of its properties.

The chemical properties of 4H-imidazolo [4,5-b] pyridine are really related to its structure and reactivity. Its unique structure is formed by fusing imidazole ring and pyridine ring, and this fused structure endows it with specific chemical stability and reaction tendency.
In terms of stability, the conjugation effect of its ring system makes it stable to a certain extent. The conjugate system can disperse the electron cloud and reduce the energy of the molecule, so under normal conditions, 4H-imidazolo [4,5-b] pyridine can maintain its own structure. However, the stability is not absolute, and its stability will also be challenged under specific conditions, such as strong acid and base, high temperature or specific reagents. < Br >
In an acidic environment, the nitrogen atom of the pyridine ring has a solitary pair of electrons, which can accept protons, so that the molecule is positively charged, which may affect its stability and reactivity. Under basic conditions, the hydrogen atom of the imidazole ring may exhibit a certain acidity, which can be captured by the base, resulting in molecular structure changes.
When it participates in chemical reactions, its stability is related to the reaction check point. Different positions of the imidazole ring and the pyridine ring have different electron cloud densities, and the electrophilic and nucleophilic reactivity are also different. For example, the β position of the pyridine ring is vulnerable to attack by electrophilic reagents due to the relatively low electron cloud density; near the nitrogen atom of the imidazole ring, due to the existence of lone pairs of electrons, it has nucleophilicity and can react with electrophilic reagents.
In summary, the chemical stability of 4H-imidazolo [4,5-b] pyridine is a relative concept. It not only has certain inherent stability, but also changes due to changes in external conditions and reaction environments. It needs to be considered in detail according to the specific situation.

4H-imidazolo [4,5-b] pyridine is also an organic compound. The method of its synthesis has been explored by many scholars in the past, and it is now also important in the academic community.
One method is to use a suitable pyridine derivative as a base, supplemented by a nitrogen-containing heterocyclic reagent, under specific reaction conditions, to make the two cross. The temperature and pressure of the reaction need to be strictly adjusted, and the appropriate solvent and catalyst should be selected to promote the smooth reaction. For example, in a study, the halogen of a pyridine and a nitrogen-containing heterocyclic reagent can be refluxed in an organic solvent under the catalysis of a base, and the yield of this compound can be obtained. < Br >
The second method starts from a simple raw material and builds its structure through a multi-step reaction. First, common small organic molecules, such as aldodes, ketones, amines, etc., are condensed and cyclized to gradually build a ring system of pyridine and imidazole. This process requires precise control of each step of the reaction to maintain the purity and configuration of the product. For example, first, the aldehyde and amine are condensed into imines, then cyclized with carbonyl-containing compounds, and then dehydrated to obtain 4H-imidazolo [4,5-b] pyridine.
The third method is catalyzed by transition metals. Transition metals such as palladium and copper can activate substrates, making the reaction easier to occur. Taking palladium catalysis as an example, suitable palladium catalysts and ligands can be selected to efficiently construct their molecular structures under mild reaction conditions. This method is often highly selective and atomic economical, making it a good strategy for synthesis.
All these methods have their own advantages and disadvantages. Researchers should carefully choose according to actual needs, such as the availability of raw materials, cost considerations, product purity and yield, etc., to achieve the best synthesis conditions.

I don't know the price range of 4H-imidazo [4,5-b] pyridine in the market. This is a rather professional chemical substance, and its price may vary due to many factors. First, purity has a great impact on its price. The price of high purity must be higher than that of low purity. Second, manufacturers also have an impact. Different manufacturers have different pricing due to differences in process and cost. Third, the market supply and demand relationship is a key factor. If demand is strong and supply is limited, prices will rise; conversely, if supply exceeds demand, prices may fall.
However, I have not found relevant information on the exact price range. If you want to know more, you can explore it on the chemical product trading platform. There may be quotations from various manufacturers on it, which can be compared. Or contact chemical raw material suppliers for consultation, they may be able to inform a more accurate price range according to the current market conditions. Or refer to relevant industry reports and information, which may include analysis of the price trend of this substance and the current price range.