4as 7as Octahydro 1h Pyrrolo 3 4 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine

    Specifications

    HS Code

    971981

    Chemical Formula C7H14N2
    Molecular Weight 126.20 g/mol
    Appearance Typically a colorless to pale yellow liquid
    Boiling Point Estimated around 190 - 200 °C (under normal pressure)
    Density Approx. 1.0 - 1.1 g/cm³
    Solubility Soluble in common organic solvents like ethanol, methanol, dichloromethane
    Vapor Pressure Low vapor pressure at room temperature
    Flash Point Moderate flash point, estimated around 70 - 80 °C
    Pka Basic nitrogen in the structure gives it a pKa value in the range of 8 - 10

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    General Information
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    Frequently Asked Questions

    As a leading (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of -octahydro-1H-pyrrolo [3,4-b] pyridine?
    The chemical structure of (4aS, 7aS) -octahydro-1H-pyrrolido [3,4-b] pyridine is particularly important. The structure of this compound is formed by the conjugation of pyrrole and pyridine. The pyrrole ring and the pyridine ring are connected in a specific way, and under the three-dimensional configuration of (4aS, 7aS), they present a unique spatial arrangement.
    The structure of the octahydro shows that there are multiple saturated carbon-carbon single bonds in the molecule, which makes the skeleton of the compound relatively stable. The naming of 1H-pyrrolido [3,4-b] pyridine reveals that where the pyrrole and the pyridine ring are conjugated, the nitrogen atom of the pyrrole ring is conjugated with the specific position of the pyridine ring. This conjugation mode affects the electron cloud distribution and chemical properties of the compound. The three-dimensional configuration of
    (4aS, 7aS) determines the spatial orientation of the molecule and has a significant impact on its interactions with other molecules, such as hydrogen bonds, van der Waals forces, etc. These structural properties make (4aS, 7aS) -octahydro-1H-pyrrolido [3,4-b] pyridine show unique application potential in organic synthesis, pharmaceutical chemistry and other fields.
    What are the main physical properties of -octahydro-1H-pyrrolo [3,4-b] pyridine?
    (4aS, 7aS) -octahydro-1H-pyrrolido [3,4-b] pyridine is an organic compound. Its main physical properties are as follows:
    Under normal temperature and pressure, this compound is mostly in the shape of white to light yellow crystalline powder, with pure appearance and uniform texture, fine and smooth, which is convenient for observation and subsequent processing.
    When the melting point is discussed, it is between 110-115 ° C. When the temperature gradually rises to this range, the compound slowly melts from solid state to liquid state. This melting point characteristic provides an important basis for the identification and purification of this substance.
    In terms of boiling point, under specific pressure conditions, the boiling point is about 280-290 ° C. When this temperature is reached, the compound changes sharply from liquid to gaseous state, and this boiling point value is of great significance for its separation and purification.
    Solubility is also a key property. In organic solvents, such as methanol, ethanol, dichloromethane, etc., the compound exhibits good solubility and can quickly and uniformly disperse into it to form a uniform solution. However, in water, its solubility is poor and only slightly soluble. This difference in solubility is widely used in chemical synthesis, drug development and other fields, and suitable solvents can be selected for reaction, separation and preparation operations. The density of
    is about 1.12-1.15 g/cm ³, reflecting the mass of the substance per unit volume. This physical parameter also has important reference value in chemical production, quality control and other links.
    (4aS, 7aS) -octahydro-1H-pyrrolo [3,4-b] In what areas is pyridine used?
    (4aS, 7aS) -octahydro-1H-pyrrolido [3,4-b] pyridine, an organic compound, has applications in many fields.
    In the field of pharmaceutical research and development, it can be used as a key intermediate. Due to its unique chemical structure, it can interact with specific targets in organisms, or has potential pharmacological activity. For example, researchers can create new drugs by modifying and modifying its structure, which can be used to treat various diseases such as neurological diseases and cardiovascular diseases. Or in pharmaceutical chemistry research, as a lead compound, it provides an important direction and foundation for the development of new drugs.
    In the field of organic synthesis, (4aS, 7aS) -octahydro-1H-pyrrole [3,4-b] pyridine is often used as a key building block. Due to its special structure, it can participate in many organic reactions, such as nucleophilic substitution, addition reactions, etc., and assist in the synthesis of more complex organic molecules. Organic chemists can use this compound cleverly to construct organic materials with special structures and functions, such as new catalyst ligands, to improve the efficiency and selectivity of catalytic reactions.
    Furthermore, in the field of materials science, with appropriate chemical modification, (4aS, 7aS) -octahydro-1H-pyrrolido [3,4-b] pyridine can be integrated into polymer materials, giving the material unique properties, such as improving the solubility and thermal stability of the material, so as to expand the application of the material in different scenarios.
    What are the synthesis methods -octahydro-1H-pyrrolo [3,4-b] pyridine?
    The synthesis method of (4aS, 7aS) -octahydro-1H-pyrrolido [3,4 -b] pyridine is related to the exquisite skills in the field of organic chemistry. This synthesis method is like exploring the ancient secret technique, which requires many studies and practices.
    One method may start from suitable starting materials and construct the core structure of pyridine through cyclization reaction. The starting materials need to be carefully selected, just like finding a suitable jade embryo. Starting with a chain compound containing appropriate substituents, under specific reaction conditions, such as with the help of suitable catalysts, it is like inviting a skilled craftsman to skillfully rearrange and close the chemical bonds in the molecule to form the basic structure of pyrrolido-pyridine. In this process, the choice of temperature and solvent is crucial, just like controlling the temperature and the environment. If the temperature is too high or too low, and the solvent is not suitable, the reaction deviation can be caused.
    Second, a step-by-step construction strategy can also be used. Synthesize the pyrrole ring part first, and then cleverly connect the pyridine ring. This is like building a delicate pavilion, building the first floor first, and then building the second floor. The synthesis of pyrrole rings can use classic organic reactions, such as aldose, amine, etc. as raw materials, through condensation and other reactions to generate pyrrole. Then, the resulting pyrrole derivative is combined with the pyridine-related intermediates, and the two are connected through a coupling reaction, etc., to construct a complete (4aS, 7aS) -octahydro-1H-pyrrolido [3,4 -b] pyridine structure. This process requires precise regulation of the reaction conditions at each step, and careful monitoring of the reaction process to obtain this target product. Each step of the reaction is like a delicate picture, and a little carelessness will lose its delicacy.
    What is the market outlook for -octahydro-1H-pyrrolo [3,4-b] pyridine?
    (4aS, 7aS) -octahydro-1H-pyrrolido [3,4-b] pyridine, this product has not been around for a long time, and its market prospect is like seeing flowers in the fog. Although there are signs emerging, it is difficult to see the whole picture.
    Looking at the market, its related research and application are still in an embryonic state. In the field of medicine, some doctors are exploring its effectiveness in neurological diseases, hoping to use its unique structure to find new ways to treat and save people. It is expected that in the future, if the research goes well, it may bring good news to many patients with serious diseases and become a sharp blade in the hands of doctors.
    In the chemical industry, there are also craftsmen pondering the possibility of its synthesis in new materials. In time, if a suitable method can be found, or new materials with outstanding performance can be spawned, it will shine in many aspects such as industrial manufacturing.
    However, the road ahead is not smooth. In the research process, the technical bottleneck is still at hand. The complexity of the synthesis process and the high difficulty of purification all require the efforts of scientific researchers to break through. And the market awareness also needs to be deepened. Many merchants and users have not yet realized its potential. The promotion of the move has a long way to go.
    Although the road is full of thorns, opportunities lurk in the meantime. If by then, everyone will be studying with one heart, and the market will be developed with one heart. (4aS, 7aS) -octahydro-1H-pyrrole [3,4-b] pyridine may emerge in the market, creating a unique scene.