4 Vinylpyridine
pyridine pyrrole pyrazine piperidine piperazine

4-vinylpyridine

    Specifications

    HS Code

    189035

    Chemical Formula C7H7N
    Molar Mass 105.14 g/mol
    Appearance Colorless to yellow liquid
    Odor Pyridine - like odor
    Density 0.981 g/cm³ at 20 °C
    Boiling Point 159 - 160 °C
    Melting Point -42 °C
    Solubility In Water Slightly soluble
    Flash Point 56 °C
    Vapor Pressure 1.33 kPa at 40.2 °C
    Refractive Index 1.545 at 20 °C

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    General Information
    Where to Buy 4-vinylpyridine in China?
    As a trusted 4-vinylpyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-vinylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-vinylpyridine?
    4-Isopropylbenzaldehyde, its main uses are as follows:
    This substance is quite useful in the field of fragrances. When blending fragrances, it can give a unique aroma. Because of its special molecular structure, it can create a fresh and characteristic fragrance atmosphere. It is often used in high-end perfumes, air fresheners and various aromatic products to add a unique fragrance and attract consumers' olfactory experience.
    In the field of organic synthesis, it is also a key intermediate. With the chemical activity of phenyl ring and aldehyde group and isopropyl group, it can participate in many complex organic reactions. For example, in the construction of complex organic macromolecules, condensation and addition reactions can occur with other compounds containing specific functional groups through the reaction characteristics of aldehyde groups, so as to build more complex organic structures for the synthesis of important organic compounds such as drugs and natural products. Like some drug molecules with specific physiological activities, 4-isopropylbenzaldehyde is used as a starting material or an important intermediate in its synthesis path, and through a series of reaction steps, a pharmaceutically active ingredient with precise structure and function is finally constructed.
    In the field of chemical materials, some of the reaction products it participates in can be applied to the preparation of polymer materials. Through chemical modification and polymerization, polymers with specific properties can be obtained, which can be used to make special plastics, coatings, etc., endowing materials with special physical and chemical properties, such as better corrosion resistance, optical properties, etc., to expand the application range of chemical materials.
    What are the physical properties of 4-vinylpyridine?
    4-Ethylpyridine is an organic compound and is a pyridine derivative. Its physical properties are as follows:
    1. ** Appearance and Properties **: At room temperature and pressure, 4-ethylpyridine is a colorless to light yellow liquid, which can be seen under specific light. It is clear and translucent, which is different from partially cloudy or heavily colored liquid compounds.
    2. ** Odor **: It has a strong and special pungent odor. It can clearly sense its unique odor when smelled. It is significantly different from common alcohols and esters. When smelled close, this pungent odor can cause nasal discomfort.
    3. ** Melting point and boiling point **: The melting point is about -63 ° C, and the boiling point is between 168-169 ° C. A lower melting point causes it to be liquid at room temperature, and a relatively high boiling point indicates that a higher temperature is required to vaporize it. For example, the boiling point of water is 100 ° C, compared with 4-ethylpyridine, which has a higher boiling point and requires more heat to boil into a gaseous state.
    4. ** Solubility **: 4-ethylpyridine can be miscible with most organic solvents such as ethanol and ether. Due to the similar principle of miscibility, it is similar to the force between organic solvent molecules and can be uniformly mixed. However, its solubility in water is limited, only slightly soluble in water, because water is a strong polar solvent, 4-ethylpyridine polarity is relatively weak, the polar difference between the two causes its solubility in water is not high.
    5. ** Density **: The density is about 0.95g/cm ³, slightly less than the density of water 1g/cm ³, if 4-ethylpyridine is mixed with water and the two do not react, 4-ethylpyridine will float on the water surface.
    What are the chemical properties of 4-vinylpyridine?
    4-Aminopyridine is an organic compound with many unique chemical properties. The following is what you said in detail:
    bears the brunt, and the alkalinity is quite significant. The amino group of 4-aminopyridine can interact with acids to form corresponding salts. Because the nitrogen atom in the amino group has lone pairs of electrons, it can accept protons and is alkaline. If it reacts with hydrochloric acid, it will form hydrochloric salts. This property is often a key step in drug synthesis. Salt formation improves drug solubility and stability.
    Furthermore, nucleophilicity is also an important property. Amino groups, as nucleophilic groups, can participate in nucleophilic substitution reactions. When they meet halogenated hydrocarbons, amino nitrogen atoms will attack the carbon atoms of halogenated hydrocarbons, and the halogen atoms will leave to form replacement products. In the field of organic synthesis, this reaction is often used to establish carbon-nitrogen bonds and expand molecular structures.
    4-aminopyridine also exhibits certain reductivity. Amino groups can be oxidized under certain conditions, such as when encountering strong oxidizing agents, the amino group may be converted to nitro or other oxidation states. This property needs to be carefully considered in some reactions involving redox steps, as it may affect the reaction process and products.
    In addition, 4-aminopyridine is prone to electrophilic substitution reactions on aromatic rings. The electron cloud density distribution of the pyridine ring itself is uneven, but the amino group as the donator group can increase the electron cloud density at specific positions on the pyridine ring, making it more susceptible to electrophilic attack. Under normal circumstances, the ortho and para-sites of amino groups are more prone to electrophilic substitution, and reactions such as halogenation and nitrification can be carried out at this position, which provides an effective way for the preparation of diverse pyridine derivatives.
    What are the synthesis methods of 4-vinylpyridine?
    4-Ethylpyridine is a commonly used intermediate in organic synthesis. There are many methods for its synthesis, which will be described in detail today.
    One is the alkylation method of pyridine derivatives. Pyridine is used as the starting material, and under suitable reaction conditions, nucleophilic substitution reaction occurs with halogenated ethane. For example, in an aprotic polar solvent (such as N, N-dimethylformamide) present in a strong base (such as potassium tert-butyl alcohol), pyridine reacts with bromoethane to form 4-ethylpyridine. The mechanism of this reaction is that the strong base captures the adjacent hydrogen atom of the pyridine nitrogen atom, generates carbon negative ions, and then attacks the carbon atom of the halogenated ethane. The halogen ions leave to complete the alkylation process.
    The second is the methylation of 4-methylpyridine. Using 4-methylpyridine as the substrate, with the help of suitable methylating reagents (such as iodomethane) and bases (such as sodium hydride), the quaternary ammonium salt of 4-methylpyridine is first formed, and then the quaternary ammonium salt of 4-ethylpyridine is reduced by reduction reaction, such as the use of reducing agents such as sodium borohydride. In this process, the methylating reagent makes the nitrogen atom of pyridine quaternary ammonium, which enhances the activity of its ortho-carbon atom, and the reducing agent realizes the purpose of converting methyl to ethyl.
    The third is the synthesis of ammonia or amine compounds with suitable alters, ketones and amines through multi- For example, using 4-pyridine formaldehyde and acetaldehyde as raw materials, the hydroxyaldehyde condensation reaction is carried out under alkaline conditions to generate unsaturated aldehyde, and then the double bond is reduced by catalytic hydrogenation, and 4-ethylpyridine is obtained by aminolysis. This route requires clever control of the reaction conditions at each step to ensure that the reaction proceeds in the desired direction and obtains a higher yield.
    The fourth is a coupling reaction method catalyzed by transition metals. Halogenated pyridine (such as 4-bromopyridine) is used to couple with vinyl Grignard reagent or vinyl borate under the action of transition metal catalyst (such as palladium catalyst) to generate 4-vinylpyridine, and then catalyzed hydrogenation to obtain the target product 4-ethylpyridine. This method relies on the unique catalytic activity of transition metal catalysts to achieve the construction of carbon-carbon bonds, and has the advantages of relatively mild reaction conditions and high selectivity.
    Different synthesis methods have their own advantages and disadvantages. In practical applications, the most suitable synthesis route should be carefully selected according to the comprehensive consideration of many factors such as raw material availability, reaction conditions, production cost and product purity.
    What are the precautions for 4-vinylpyridine during storage and transportation?
    4-Isopropyl benzaldehyde during storage and transportation, when paying attention to all things, can ensure its quality and safety.
    When storing, the first choice of environment. It should be placed in a cool and ventilated place, away from fire and heat sources. Because of its flammability, if it is heated or exposed to open flames, it is easy to cause fire risk. The warehouse temperature should be controlled within an appropriate range. If it is too high temperature or causes it to evaporate and even undergo chemical changes. And it needs to be sealed and stored to prevent contact with air. Because its aldehyde group is active, it is easy to be oxidized and cause quality damage. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., to avoid chemical reactions caused by mixed storage.
    When transporting, there are also many precautions. It is necessary to ensure that the packaging is complete and the loading is safe. The packaging materials should have good sealing and corrosion resistance to prevent leakage. During transportation, the traffic should be stable to avoid bumps and vibrations to prevent packaging damage. Transportation vehicles should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. In the event of an accident, they can be responded to in time. In addition, transport personnel need to be familiar with its characteristics and emergency treatment methods. The transportation route should avoid densely populated areas and important facilities to reduce latent risks. Only by being careful in storage and transportation can 4-isopropylbenzaldehyde be kept safe and of the same quality.