4 Tert Butyl 2 Chloropyridine
pyridine pyrrole pyrazine piperidine piperazine

4-(tert-butyl)-2-chloropyridine

    Specifications

    HS Code

    786253

    Chemical Formula C9H12ClN
    Molecular Weight 171.65
    Appearance Typically a solid or liquid (specific color and state may vary based on purity and conditions)
    Solubility In Water Low solubility, as it is an organic heterocyclic compound with non - polar tert - butyl group
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene etc.

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    Frequently Asked Questions

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    What is the main use of 4- (tert-butyl) -2-chloropyridine?
    4- (tert-butyl) -2-chloropyridine is a crucial chemical substance in the field of organic synthesis. Its main uses can be described in detail as follows.
    First, in the field of pesticide creation, this compound plays a pivotal role. Gai is often used as a key intermediate for the synthesis of new pesticides because of its unique structure and specific biological activities. By combining it with other functional groups through clever organic synthesis methods, a series of pesticide products with high insecticidal, bactericidal or herbicidal properties can be derived. These pesticides can not only effectively prevent and control crop diseases and pests, ensure the robust growth of crops, improve the yield and quality of agricultural products, but also have lower toxicity and environmental friendliness than traditional pesticides, which is in line with the general trend of today's green agriculture development.
    Second, in the field of medicinal chemistry, 4- (tert-butyl) -2-chloropyridine also occupies a place. Due to the similarity between its molecular structure and some bioactive molecules, researchers can use this as a basis for drug research and development. After structural modification and optimization, lead compounds with specific pharmacological activities can be created, and new drugs for treating various diseases, such as antibacterial drugs, anti-inflammatory drugs, etc., can be developed, contributing to human health.
    Third, in the field of materials science, the compound also shows potential application value. Through specific chemical reactions, it can be introduced into the structure of polymer materials, giving the material unique physical and chemical properties, such as improving the stability, solubility or optical properties of the material. This helps to develop new functional materials, which can be applied to electronic devices, optical materials and many other fields to promote the progress and development of materials science.
    To sum up, 4- (tert-butyl) -2-chloropyridine has become an attractive organic compound in chemical research and industrial production due to its extensive and important uses in pesticides, medicine and materials.
    What are the physical properties of 4- (tert-butyl) -2-chloropyridine?
    4- (tert-butyl) -2-chloropyridine is one of the organic compounds. Its physical properties can be investigated.
    Looking at its morphology, it is mostly liquid at room temperature and pressure, with a clear texture and specific flow characteristics. Its color is often close to colorless, but it may change slightly yellow due to the presence of impurities.
    As for its smell, it has a special smell. This smell is given by the molecular structure of the compound, and the smell is different depending on the concentration.
    When it comes to boiling point, this compound has a specific value. Due to factors such as intermolecular forces, its boiling point makes it change from liquid to gaseous at a certain temperature. The number of boiling points is related to the process of separation, purification and application.
    Melting point is also an important physical property. At a certain temperature, this substance melts from solid to liquid, and this melting point value is closely related to the arrangement and interaction of molecules.
    In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether. Due to the principle of similar miscibility, its organic structure is in agreement with the molecular structure of organic solvents. However, in water, the degree of solubility is relatively limited, due to the difference between the polarity of water and the structure of the compound.
    Density is also one of its characteristics. The density value reflects the mass of the substance per unit volume, which is of great significance in many application scenarios, such as mixing and separation.
    The physical properties of 4- (tert-butyl) -2-chloropyridine are key factors to consider in many fields such as chemical research and industrial production, and are related to various processes of its preparation, separation and application.
    What is the chemical synthesis method of 4- (tert-butyl) -2-chloropyridine?
    The method of preparing 4- (tert-butyl) -2 -chloropyridine is an important task in organic synthesis. The synthesis method follows several common paths.
    First, it can be started from pyridine derivatives. First, take an appropriate pyridine substrate, introduce chlorine atoms at the 2nd position of the pyridine ring, and introduce tert-butyl atoms at the 4th position. Introducing chlorine atoms, often with chlorinated reagents, such as phosphorus oxychloride, under suitable reaction conditions, make the pyridine ring undergo electrophilic substitution reaction, and introduce chlorine atoms at the 2nd position. As for the access to tert-butyl, tert-butyl can be used, such as tert-butyl halide, in the presence of suitable bases and catalysts, through nucleophilic substitution reaction, tert-butyl is attached to the fourth position of the pyridine ring. In this process, the choice of base is very critical. Potassium carbonate, potassium tert-butyl alcohol, etc. are commonly used, which can promote the reaction and affect the selectivity of the reaction.
    Second, you can also start with the construction of the pyridine ring. With suitable raw materials containing tert-butyl and chlorine atoms, a pyridine ring is constructed through a multi-step reaction. For example, compounds containing functional groups such as carbonyl and amino groups can be used to form pyridine rings through a series of reactions such as condensation and cyclization, and tert-butyl and chlorine atoms can be subtly introduced into the target position. This path requires precise control of reaction conditions, such as reaction temperature, reaction time, and the ratio of reactants, which will affect the efficiency and selectivity of pyridine ring construction.
    In the process of synthesizing 4- (tert-butyl) -2-chloropyridine, the reaction conditions at each step need to be carefully optimized to improve the yield and purity of the product. The separation and purification after the reaction is also indispensable. Methods such as column chromatography and recrystallization are often used to effectively separate the target product from the reaction mixture to obtain pure 4- (tert-butyl) -2-chloropyridine.
    What are the precautions for 4- (tert-butyl) -2-chloropyridine during storage and transportation?
    4- (tert-butyl) -2-chloropyridine is also an organic compound. During storage and transportation, many matters must be paid attention to.
    Bear the brunt, when storing, must choose a cool, dry and well-ventilated place. This compound is afraid of moisture and moisture. If it is in a humid environment, it may react with water vapor, causing its quality to be damaged. In addition, temperature is also very important. Excessive temperature may cause its chemical changes, so it should be controlled within an appropriate range.
    Second, it has a certain chemical activity, and should be avoided from contact with strong oxidants, strong acids, strong bases and other substances during storage. When these substances meet them, they can easily trigger violent chemical reactions or be dangerous. Such as strong oxidizing agents or cause oxidation, change the chemical structure, and cause the risk of combustion and explosion.
    When transporting, the packaging must be solid and reliable. Special containers must be used to ensure that they are well sealed to prevent leakage. If it leaks during transportation, it will not only pollute the environment, but also pose potential hazards to surrounding organisms and people.
    Furthermore, transporters should also be familiar with its characteristics and emergency response methods. In case of emergencies, such as leakage, fire, etc., correct measures can be taken quickly to reduce the damage.
    In conclusion, 4- (tert-butyl) -2-chloropyridine needs to be treated with caution in terms of storage and transportation, environment, contacts, packaging, and personnel handling, so as to ensure safety.
    What are the effects of 4- (tert-butyl) -2-chloropyridine on the environment and human health?
    4- (tert-butyl) -2-chloropyridine is one of the organic compounds. As for its impact on the environment and human health, there are few previous studies, so today we will try to analyze it.
    At the environmental end, this compound may be difficult to decompose in the natural environment due to its chemical properties and is easy to accumulate. If it flows into the water body, it may cause aquatic organisms to suffer from it. Aquatic organisms have limited tolerance to foreign bodies. This compound may interfere with their physiological metabolism, damage their cell tissue, and even cause changes in population size. It may flow into the soil, or change the chemical properties of the soil, hindering the uptake of nutrients by plant roots, which in turn affects the growth of vegetation.
    In terms of human health, although there is no detailed conclusion, it is analogous to similar structural compounds, which may pose a potential threat. If ingested by humans through breathing, diet, or skin contact, it may affect the nervous system. The nervous system, the cardinal of the human body, is in charge of perception, movement, and thinking. This compound may interfere with the transmission of neurotransmitters, causing people to feel dizzy and sluggish. Long-term exposure, or involving the immune system, can reduce the body's ability to resist disease and make it susceptible to diseases.
    In addition, it spreads in the environment or enriches through the food chain. Humans are at the top of the food chain, or due to the consumption of contaminated organisms, the amount of this compound in the body gradually increases, and the harm is becoming more and more obvious.
    In summary, although the research on 4- (tert-butyl) -2-chloropyridine is not complete, its potential impact on the environment and human health cannot be ignored. In the future, we should increase the research power to understand its nature and harm, so as to ensure the peace of the environment and the health of the human body.