4 Pyridylpyridine
pyridine pyrrole pyrazine piperidine piperazine

4-pyridylpyridine

    Specifications

    HS Code

    891140

    Chemical Formula C10H8N2
    Molar Mass 156.184 g/mol
    Appearance Solid
    Color White to off - white
    Odor Odorless
    Melting Point 85 - 88 °C
    Boiling Point 278 - 280 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Density 1.106 g/cm³
    Pka Value Around 4.7
    Crystal Structure Monoclinic
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

    As a leading 4-pyridylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4-pyridylpyridine?
    4-Pyridyl pyridine is one of the organic compounds. Its molecular structure is unique, composed of two pyridine rings connected by a specific chemical bond. The dipyridine ring, one of which is directly related to the other pyridine ring at position 4.
    The pyridine ring is a nitrogen-containing six-membered heterocyclic ring structure with aromatic properties. The nitrogen atom in the ring has a unique electronic effect, which affects the chemical properties of the whole molecule. In 4-pyridyl pyridine, the two pyridine rings interact, causing the compound to exhibit very different properties from a single pyridine.
    This structure endows 4-pyridyl pyridine with various chemical activities and physical properties. Due to its nitrogen-containing atoms, it can be used as electron donors to form coordination bonds with metal ions, etc., which has attracted much attention in the field of coordination chemistry. And because of the extension of its conjugate system, it also shows unique performance in photophysical properties, such as fluorescence emission, and has potential application value in research directions such as optoelectronic materials. Its exquisite chemical structure lays the foundation for many scientific research and application development.
    What are the main uses of 4-pyridylpyridine?
    4-Pyridyl pyridine has a wide range of uses. In the field of chemical synthesis, it is often used as a ligand. Due to its nitrogen-containing heterocycle structure, it has unique electronic properties and can coordinate with metal ions. This is essential in the catalytic reaction of metal-organic chemistry. For example, in some coupling reactions, it can be combined with metal catalysts to effectively improve the reactivity and selectivity, so that the reaction can be carried out efficiently, and many organic compounds with specific structures can be synthesized.
    In the field of materials science, 4-pyridyl pyridine also has important applications. It can participate in the construction of functional materials, such as in the preparation of porous materials. With its own structural characteristics, it can adjust the pore structure and properties during the material formation process, so that the material exhibits excellent performance in gas adsorption and separation. Furthermore, in the field of luminescent materials, due to the influence of this substance on the molecular structure and electron cloud distribution, the luminescent properties of materials can be optimized, and materials with specific luminescent wavelengths and intensities can be prepared, which can be used in lighting, display and many other aspects.
    In addition, in the biomedical research part, 4-pyridyl pyridine may also have potential value. Although its structural properties or its interaction with specific targets in organisms have not been fully explored, studies have suggested that it may be an important starting point in the direction of drug development, or it may be able to develop new therapeutic drugs for the fight against various diseases.
    What are the physical properties of 4-pyridylpyridine?
    4-Pyridyl-pyridine is an organic compound. It has unique physical properties and is worth studying.
    Looking at its properties, it may be solid under normal conditions and has a certain crystalline form. Its color may be white to slightly yellow, and its texture may be powdery. Because of its orderly arrangement of molecular structures, its condensed state is like this.
    When it comes to the melting point, it has been measured by various experiments that it is in a certain temperature range. This temperature characterizes the strength of the intermolecular force. When heated to the melting point, the molecule is energized enough to break free from the lattice and transfer from the solid state to the liquid state.
    Solubility is also an important physical property. In polar solvents, such as alcohols, because their molecules contain polar groups, they can interact with polar solvent molecules to form hydrogen bonds, etc., so they have a certain solubility; however, in non-polar solvents, such as alkanes, due to the large difference in the force between the two molecules, their solubility is very small.
    Its density is also a specific value, reflecting the mass of the substance per unit volume, which is closely related to the degree of molecular accumulation.
    In addition, the vapor pressure of 4-pyridyl pyridine has different values at different temperatures. When the temperature increases, the vapor pressure increases, indicating that the tendency of molecules to escape from the liquid or solid state to the gas phase increases.
    In summary, the physical properties of 4-pyridyl pyridine are determined by its molecular structure, and it has important uses in many fields of chemistry and materials due to its unique physical properties.
    What are the synthesis methods of 4-pyridylpyridine
    4-Pyridyl pyridine, also known as bipyridine, has many wonderful methods in the past. First, it can be obtained from pyridine through a specific reaction. First, the pyridine is condensed under specific conditions with a suitable catalyst. Here, temperature and pressure are all important factors and need to be precisely controlled. If the temperature is too high, it may cause side reactions to increase and the product is impure; if the temperature is too low, the reaction will be slow and take a long time. The pressure also needs to be moderate to make the reaction smooth.
    Second, halogenated pyridine is used as the raw material. Mix halogenated pyridine and suitable reagents in a suitable solvent in a certain proportion. The structure of 4-pyridyl-pyridine is gradually constructed through reactions such as nucleophilic substitution. During this period, the choice of solvent is very critical, and it needs to have good compatibility with the reactants and products without interfering with the reaction process. The purity and activity of the reagents used also have a great impact on the reaction effect.
    Third, the method of metal catalysis is used. With the help of the unique activity of metal catalysts, the bonding between related reactants is promoted. Among them, the type of metal and the design of ligands need to be carefully considered. The appropriate metal-ligand combination can greatly improve the selectivity and efficiency of the reaction. However, the cost and recycling of metal catalysts are also important factors to be weighed in practical operation.
    All these synthesis methods have their own advantages and disadvantages, and careful choices are required according to actual needs, such as product purity, cost considerations, and ease of control of reaction conditions, in order to achieve efficient synthesis of 4-pyridyl pyridine.
    What are the precautions for using 4-pyridylpyridine?
    For 4-pyridyl pyridine, all matters need to be paid attention to when it is used. Its sex is special, or it may be potentially dangerous. Between handling, the first protective gear should be used. Appropriate protective clothing should be worn to prevent it from causing damage to the skin; appropriate gloves should be worn to avoid direct contact with the skin; protective goggles should be worn to protect the eyes from invasion.
    Furthermore, it may be irritating. Make sure that the place where you are located is well ventilated. If you use it in the room, install a ventilation device to prevent gas accumulation. If you inhale it accidentally, leave the scene quickly and go to a place with fresh air. If you feel unwell, seek medical attention urgently.
    Also, 4-pyridyl pyridine plays a different role in the reaction. When using it, it must be in the exact amount and according to the standard method. Due to improper dosage, the reaction may deviate from expectations, or cause unexpected changes. And it is mixed with other things, or there are other reactions. Check the physical properties carefully before use, and be familiar with the application of it and various things, so as to ensure the safety and certainty of use.
    Furthermore, when storing, you should also pay attention. It should be stored in a cool, dry and well-ventilated place, protected from fire and heat, to prevent its properties from changing, and to ensure its quality. After taking it, keep it sealed to avoid biochemical changes due to long-term contact with the air. Pay attention to such things, so that you can use it properly and avoid all kinds of worries.