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What are the main uses of 4-pyridinepropanol?
4-Pyridyl-propanol is a kind of chemical and has a wide range of uses. In the field of medicine, it is often used as a raw material for the creation of drugs. Due to its special chemical structure, it can participate in various reactions to produce compounds with pharmacological activity. For example, in the research and development of drugs for the nervous system, it can be used to treat related diseases by its structural properties.
In the realm of organic synthesis, 4-pyridyl-propanol is a key intermediate. It can be derived from other organic compounds through many reaction pathways. For example, by esterification, alkylation and other reactions, the molecular structure is expanded and its function is increased. It is an important starting material for the synthesis of complex organic molecules and plays an important role in the chemical industry.
Furthermore, in the field of materials science, 4-pyridyl propanol may also be. Or can participate in the synthesis of polymers, giving materials special properties. For example, improve the solubility and stability of materials, so that the materials are more suitable for specific scenarios, such as the preparation of coatings, plastics, etc.
In addition, in the process of chemical research, 4-pyridyl propanol can be used as a model compound. Help researchers explore chemical mechanisms and reaction laws. Because of its typical structure, studying its reaction characteristics can be extended to similar compounds, adding to the improvement of chemical theory. In short, 4-pyridyl propanol has important uses in medicine, synthesis, materials and scientific research.
What are the physical properties of 4-pyridinepropanol?
4-Pyridyl-propanol is also an organic compound. It has the following physical properties:
Viewed at room temperature, it is mostly a colorless to light yellow liquid, with a clear appearance, which can be seen as a clear liquid flow, no suspended impurities, and a warm luster.
Smell it, emits a special smell. This smell is not pungent or elegant, but a unique smell. However, it is not easy to describe it accurately, and it seems to contain some fragrant smell, lingering between the noses.
As for its melting point, it has a low melting point and is still liquid in common low temperature environments, not easy to solidify; the boiling point is relatively high, and a higher temperature is required to make it boil into a gaseous state. This property allows it to exist stably in a liquid state under normal conditions.
In terms of solubility, 4-pyridyl propanol is soluble in many organic solvents, such as ethanol, ether, etc., just like fish entering water, the two are inseparable. Due to the similar miscibility principle, its molecular structure is compatible with organic solvents, so it can be miscible with each other. In water, it also has a certain solubility, but the solubility is not very high, showing a partially dissolved state, forming a uniform dispersion system in water.
The density is slightly larger than that of water. If it is placed in the same container as water and left to stand for a while, it can be seen that it slowly sinks to the bottom of the water, like a stone falling into the abyss pond. This is the manifestation of its density characteristics.
The above are all common physical properties of 4-pyridyl-propanol, which are crucial in chemical research and practical applications, laying the foundation for related operations and reactions.
What are the chemical properties of 4-pyridinepropanol?
4-Pyridyl propanol has mild properties and special chemical properties. This substance is an organic compound whose molecular structure contains a pyridine ring and a side chain of propanol, which are connected to give it unique properties.
From the perspective of physical properties, 4-pyridyl propanol is mostly liquid at room temperature, with a certain volatility and a special odor. Its solubility is quite characteristic, it can be soluble in many organic solvents, and it also has a certain solubility in water, because there are both hydrophilic hydroxyl groups and hydrophobic pyridyl rings and alkyl groups in the molecule.
When it comes to chemical properties, its pyridine ring is aromatic and can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. The nitrogen atom of the pyridine ring can provide electron pairs, so the substance has a certain alkalinity and can form salts with acids. The hydroxyl activity of the side chain of propanol should not be underestimated. It can participate in the esterification reaction, react with carboxylic acids or anhydrides to form corresponding esters, and can be oxidized under appropriate conditions. Depending on the type of oxidant and the reaction conditions, it can be oxidized to an aldehyde or carboxylic acid.
In addition, 4-pyridyl propanol can be used as an important intermediate in organic synthesis due to its multiple activity checking points. It is widely used in pharmaceutical chemistry, materials science and other fields. It can construct complex organic molecular structures through its unique chemical properties and provide assistance for the development of many fields.
What is the production method of 4-pyridinepropanol?
For 4-pyridyl propanol, there are several ways to prepare it. One method starts with pyridine and allyl halide, and is obtained by the reaction of nucleophilic substitution. The nitrogen atom of pyridine has nucleophilic properties and can attack the halogenated carbon of allyl halide. The halogen ions leave and form bonds to obtain the precursor of 4-pyridyl propanol. Later or through steps such as hydrogenation, the unsaturated bond is saturated, and 4-pyridyl propanol is finally obtained.
There are also those who use 4-pyridyl propionic acid as raw material. 4-Pyridyl propionic acid is first reacted with a suitable reducing agent, such as sodium borohydride-boron trifluoride ether complex, in a suitable solvent, such as anhydrous tetrahydrofuran, at low temperature and under stirring conditions. The reducing agent reduces the carboxyl group to an alcoholic hydroxyl group, and then 4-pyridyl propionic alcohol is obtained. This process requires attention to the reaction temperature and the amount of reagents to prevent excessive reduction or side reactions.
There are also those prepared from 4-pyridyl propionic aldehyde. With a suitable reducing agent, such as sodium borohydride, in an alcohol solvent, the carbonyl group of 4-pyridyl propionic aldehyde is reduced to a hydroxyl group, and 4-pyridyl propionic alcohol can be obtained. The reaction conditions are mild, and the purity of the product is easier to control. However, the selection of raw materials and the regulation of reaction conditions are all related to the yield and purity of the product. When preparing, it should be carefully considered.
What is the price range of 4-pyridinepropanol in the market?
4-Pyridyl propanol is in the market, and its price range is difficult to determine. The price of this chemical often changes for many reasons. First, the state of supply and demand is left and right. If there are many people seeking it, but the supply is limited, the price will increase; conversely, if the supply exceeds the demand, the price may drop. Second, its manufacturing cost is also a major factor. The price of raw materials, manufacturing methods, energy consumption, etc. are all related to cost, which in turn affects the price. Third, the competitive situation of the market also plays a role. If there are many products in the market, the competition is fierce, and the price may be adjusted for the market.
Looking at the past market conditions, the price of 4-pyridyl propanol fluctuates. At some point, or tens of yuan per kilogram; then in other situations, or due to the shortage of raw materials, manufacturing difficulties, etc., the price rises to more than 100 yuan per kilogram or even higher. However, the current price is difficult to determine based on past practice. It is necessary to check the market in real time, consult suppliers, traders, or refer to the chemical product information platform, in order to get a near-real price range.