4 Pyridinemethanol Hydrochloride
pyridine pyrrole pyrazine piperidine piperazine

4-Pyridinemethanol hydrochloride

    Specifications

    HS Code

    409528

    Chemical Formula C6H8ClNO
    Molar Mass 145.59 g/mol
    Appearance White to off - white solid
    Solubility Soluble in water
    Purity Typically high - purity in commercial products (e.g., >98%)
    Melting Point 215 - 219 °C
    Odor Odorless or very faint odor
    Ph In Solution Acidic
    Stability Stable under normal storage conditions
    Hazard Class Irritant (may cause skin, eye and respiratory irritation)

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    General Information
    Where to Buy 4-Pyridinemethanol hydrochloride in China?
    As a trusted 4-Pyridinemethanol hydrochloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Pyridinemethanol hydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Pyridinemethanol hydrochloride?
    4 - Pyridinemethanol hydrochloride is also an organic compound. It has a wide range of uses and plays a significant role in the field of medicine and chemical industry.
    It is often used as a key intermediate in the synthesis of drugs. The structural characteristics of the gainpyridine ring and methanol group give it unique reactivity, and it can ingeniously react with many reagents to build various complex drug molecular structures. For example, when developing specific antibacterial drugs, it can be used to participate in the reaction, introduce key structural fragments, and then improve the antibacterial efficacy and selectivity of drugs.
    In the field of materials science, it also has extraordinary performance. It can be modified by specific reactions to give materials unique properties. For example, it can be used to prepare functional polymer materials, which can improve the solubility, stability and biocompatibility of materials, and give new uses to materials, such as degradable materials in the biomedical field, drug sustained-release carriers, etc.
    And in chemical research experiments, it is a commonly used reagent. It can provide specific reaction check points and chemical environments for organic synthesis reactions, help researchers explore novel reaction paths and methods, and promote the continuous development and progress of organic chemistry. In short, 4-Pyridinemethanol hydrochloride plays an important role in many fields, and is of great significance to the development of science and technology and production practice.
    What are the physical properties of 4-Pyridinemethanol hydrochloride
    4 - Pyridinemethanol hydrochloride is an organic compound whose physical properties are crucial and relevant to many practical applications. This compound is often in a solid state at room temperature, and its appearance may be a white crystalline powder with a fine texture, just like the pure appearance of the first snow in winter.
    Looking at its solubility, it dissolves well in water, just like snowflakes merging into a stream, quietly disappearing. This property is due to the interaction between its molecular structure and water molecules, which can form hydrogen bonds with water, so it is easy to disperse in water to form a uniform solution. And it also shows some solubility in polar organic solvents, such as ethanol, acetone, etc., but the solubility may vary depending on the type of solvent and temperature.
    When it comes to melting point, 4-Pyridinemethanol hydrochloride has a relatively clear melting point value, which is an important indicator for identifying its purity. When heated to a specific temperature, it changes from solid to liquid, just like ice and snow melting, and the phase state changes. Generally speaking, the melting point range of pure products is relatively narrow. If impurities are mixed in, the melting point may decrease and the melting range will become wider.
    In addition, the compound also has a certain degree of hygroscopicity. In humid air, it is like a sponge absorbing water, which easily absorbs water and causes its own deliquescence. This requires that during storage and use, attention should be paid to the dryness of the environment to avoid affecting its quality and performance. In conclusion, the physical properties of 4-Pyridinemethanol hydrochloride play a crucial role in its storage, transportation, and various chemical reactions and practical applications.
    What are the chemical properties of 4-Pyridinemethanol hydrochloride
    4 - Pyridinemethanol hydrochloride is also an organic compound. Its properties are multiple and quite specific.
    In terms of its physical properties, this compound is often in a solid state, at room temperature, or in the shape of white crystals. When the texture is relatively pure, the appearance is uniform and delicate. Its melting point, boiling point and other properties are fixed due to the force between molecules. The value of the melting point is related to the energy required for the molecule to break free from the lattice binding, which can be a key indicator for the identification of this substance.
    As for the chemical properties, its reactivity is quite unique due to the presence of pyridine rings and hydroxymethyl groups. Pyridine rings are aromatic, and the distribution of electron clouds is special, so that electrophilic substitution reactions can occur on the rings, such as halogenation and nitrification. Hydroxymethyl can participate in a variety of organic reactions, such as esterification. Under the catalysis of acid, it can react with carboxylic acids to form corresponding esters, which is a commonly used way in organic synthesis. And because it is a hydrochloride, it has the versatility of salt, can be dissociated in water, and can neutralize with bases to generate 4-Pyridinemethanol and corresponding salts and water. In the field of organic synthesis, this substance is often an important intermediate. Through various reactions, more complex organic molecular structures can be constructed, which makes great contributions to the preparation of drugs, functional materials, etc. The diversity of its chemical properties is the focus of organic chemistry research and application.
    What is the production method of 4-Pyridinemethanol hydrochloride?
    The preparation method of 4-pyridine methanol hydrochloride has been used throughout the ages. One of the commonly used methods is to use pyridine as a base and obtain it through multi-step reaction.
    Take pyridine first, and put an appropriate amount of formaldehyde in a suitable reaction kettle. Using a base as a catalyst, control the temperature moderately to make it undergo nucleophilic addition reaction. In this reaction, the nitrogen atom of pyridine is nucleophilic and can interact with the carbonyl carbon of formaldehyde to gradually form a pyridine derivative containing hydroxyl groups. The temperature should not be too high or too low. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow, often controlled between tens of degrees Celsius. < Br >
    Then, the obtained hydroxypyridine-containing derivatives are acidified with appropriate acids. Hydrochloric acid is a commonly used acid. When adding hydrochloric acid dropwise, it needs to be slowly and constantly stirred to make the reaction sufficient, and finally 4-pyridyl methanol hydrochloride is obtained. The acidification process requires attention to the pH value of the reaction system, and the reaction is stopped in time to obtain a high-purity product.
    There are also other methods, such as using a pyridyl derivative containing a specific substituent as the starting material and converting the functional group, 4-pyridyl methanol hydrochloride can also be prepared. However, in these methods, the raw materials may be more difficult to obtain, and the process may be more complicated, so the previous method is more commonly used. At the time of preparation, the reaction conditions of each step, such as temperature, reactant ratio, reaction time, etc., must be carefully controlled to obtain high-quality 4-pyridyl methanol hydrochloride.
    4-Pyridinemethanol hydrochloride during storage and transportation
    4-Pyridyl methanol hydrochloride is a chemical substance. When storing and transporting, many matters need to be paid attention to.
    First word storage. This substance should be placed in a cool, dry and well-ventilated place. Because it is afraid of moisture, if it is in a humid environment, it may cause deterioration. It should be stored away from light and shade, and light or chemical reactions will damage its quality. And it should be stored in isolation from oxidants, acids, alkalis, etc., to prevent interaction and danger. The storage place should be prepared with suitable containment materials. In case of leakage, it can be cleaned up in time.
    Second talk about transportation. When transporting, make sure that the container does not leak, collapse, fall, or damage. It should be driven according to the specified route, and do not stop in densely populated areas and busy cities for a long time. Transport vehicles must be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. The handling process must be light and light, beware of damage to packaging and containers.
    In short, during the storage and transportation of 4-pyridyl methanol hydrochloride, it is necessary to strictly abide by norms and operate with caution to ensure the safety of personnel and material integrity, and avoid dangerous accidents.