4-Pyridinemethaneamine

4-Pyridylmethylamine, this is one of the organic compounds. In terms of physical properties, it is mostly liquid at room temperature and has a specific odor. In terms of solubility, it is slightly soluble in water, but easily soluble in many organic solvents, such as ethanol and ether. Due to the similar miscibility, its molecular structure characteristics make it more compatible with organic solvents.
In terms of its chemical properties, the amino groups in 4-pyridylmethylamine are quite active. Amino groups are rich in lone pairs of electrons and easily combine with protons, so they are alkaline. When exposed to acids, they can react with them to form corresponding salts. This is a typical reaction of acid-base neutralization, just like acid and base meeting and interacting to achieve a new chemical equilibrium.
In addition, the pyridine ring of this substance also has unique reactivity. The pyridine ring has aromatic properties, but compared with the benzene ring, the electron cloud distribution is different, resulting in slightly lower electrophilic substitution reactivity. However, under suitable conditions, electrophilic substitution reactions such as halogenation and nitrification can still occur. The difference in electron cloud density on the pyridine ring determines the selectivity of the reaction check point, which is an important manifestation of the relationship between structure and reactivity in organic chemistry.
At the same time, the amino group of 4-pyridylmethylamine can participate in many organic synthesis reactions, such as reacting with acid halides and anhydrides to form amides. Such reactions are widely used in the field of organic synthesis, providing an important way for the preparation of various nitrogen-containing organic compounds, as a key step in building a chemical molecular edifice. Through these reactions, organic molecules with rich and diverse structures can be constructed.

4-Pyridinemethaneamine, or 4-pyridylamine, has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate for the synthesis of many drugs. The special structure of the pyridine ring and methylamine group endows the drug with unique biological activities and pharmacological properties. For example, when developing antibacterial drugs, 4-pyridylamine can be chemically modified to access drug molecules to enhance the affinity and effect of the drug on specific bacterial targets, and help fight infectious diseases.
In the field of materials science, 4-pyridylamine also has important uses. First, it can be used as a ligand to coordinate with metal ions to construct metal-organic framework materials (MOFs) with diverse structures and unique properties. Such MOFs materials have excellent performance in the field of gas adsorption and separation due to their high specific surface area and regular pore structure. For example, they can efficiently adsorb and separate gases such as carbon dioxide and hydrogen, which is of great significance for environmental protection and energy storage. Second, some organic polymer materials involved in the synthesis of 4-pyridylamine have good electrical and optical properties, and can be applied to optoelectronic devices such as organic Light Emitting Diode (OLED) and solar cells to improve device performance and efficiency.
In addition, in organic synthesis chemistry, 4-pyridylamine is an important building block for the construction of complex organic molecules. With the reactivity of active amino groups and pyridine rings, different functional groups can be introduced through various organic reactions, such as nucleophilic substitution and condensation reactions, to synthesize organic compounds with complex structures and different functions, providing a rich material basis for the development of organic synthetic chemistry.

4-Pyridylmethylamine is also an organic compound. The synthesis methods of the past are various, and they vary depending on the raw materials and purposes.
One method uses 4-cyanopyridine as the starting material. The first 4-cyanopyridine in a suitable solvent, such as ethanol or methanol, in case of a reducing agent, such as a mixture of sodium borohydride and nickel chloride, this agent can be cyanylated to aminomethyl, the reaction time, temperature control in a moderate environment, usually at room temperature or slightly heated, about 40-60 degrees Celsius, after several times of reaction, the cyanyl group is gradually reduced to aminomethyl, 4-pyridyl methylamine can be obtained, but after the reaction is completed, it needs to be separated and purified by steps such as extraction, distillation or chromatography to obtain a purified product.
Another method starts with 4-pyridyl formaldehyde. 4-Pyridine formaldehyde reacts with ammonia and reducing agents, such as sodium cyanoborohydride, in a suitable solvent, such as dichloromethane. Sodium cyanoborohydride can promote the reductive amination reaction of ammonia and aldehyde groups. This reaction also needs to be controlled at temperature. It is about room temperature. After several times, the aldehyde group is converted into aminomethyl groups to obtain 4-pyridine methylamine. Thereafter, it also needs to be purified to remove impurities and obtain a pure product.
Then there are those who use 4-halogenated pyridine as a raw material. 4-Halogenated pyridine and nucleophiles, such as sodium cyanide, first obtain 4-cyanopyridine, and then cyanylate to aminomethyl groups according to the previous method. The reaction of halogenated pyridine with sodium cyanide needs to be carried out in an appropriate solvent and temperature, and then through a reduction step, 4-pyridylmethylamine can be obtained, and finally it needs to be purified to achieve the desired purity.

4-Pyridylmethylamine is a chemical substance. During storage and transportation, there are a number of things that should be paid attention to and should not be ignored.
First words storage. Because of its active nature, it should be stored in a cool, dry and well-ventilated place. If it is placed in a high temperature and humid place, it may cause deterioration. And it needs to be kept away from fires and heat sources, because the material is flammable, and it is easy to cause the risk of combustion in case of open flames and hot topics. In addition, it should be stored separately from oxidants, acids, etc. These substances come into contact with it, or react violently, causing accidents. The storage place also needs to be prepared with suitable materials to contain leaks to prevent accidents.
Second talk about transportation. Before transportation, be sure to ensure that the packaging is complete and sealed to prevent leakage during transportation. Vehicles used during transportation should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain and high temperature. When road transportation, follow the prescribed route and do not stop in residential areas and densely populated areas. When rail transportation, do not slip away.
In short, the storage and transportation of 4-pyrimethylamine should be treated with caution, in accordance with relevant regulations, so that the security is safe and the disaster will not occur.

The market price range of 4-Pyridinemethaneamine, or 4-pyridylamine, varies depending on a variety of factors. The price of this substance is often determined by the cost of raw materials, the difficulty of preparation process, and market supply and demand conditions.
If the raw materials are easy to obtain, the preparation process is mature and simple, and the market supply is sufficient and the demand is stable, the price may be relatively close to the people. Conversely, if the raw materials are scarce, the preparation process is complicated, special technology and equipment are required, and the market demand is strong and the supply is limited, the price will rise.
In terms of the current market situation, the price of 4-pyridylamine ranges from a few yuan to tens of yuan per gram. Purity is a key factor affecting the price, and the price of high-purity products is much higher than that of ordinary purity. For example, the purity of about 95%, or 5 yuan to 15 yuan per gram; purity of 99% and above, or 15 yuan to 30 yuan per gram or even higher.
In addition, the purchase volume also affects the price, bulk purchase due to scale effect, the price per gram is more favorable than a small purchase. Purchasing channels also have an impact. Purchasing from regular large chemical raw material suppliers, although the quality is guaranteed, the price may be slightly higher; from some small suppliers or special channels, the price may be favorable, but the quality and supply stability are questionable. To sum up, the market price range of 4-pyridylmethylamine fluctuates greatly, roughly between a few yuan to tens of yuan per gram.