4-Pyridineethanesulphonic acid

4-Pyridyl ethanesulfonic acid is a very important chemical substance and has a wide range of uses in many fields.
In the field of biochemical research, it is often used as a buffer. Chemical reactions in organisms need to be carried out smoothly in a specific pH environment. The buffering performance of 4-pyridyl ethanesulfonic acid can effectively maintain the pH stability of the reaction system and avoid adverse effects on the structure and function of biological macromolecules due to large fluctuations in pH. For example, in the research experiments of biological macromolecules such as proteins and nucleic acids, the stability of the buffer system depends on the accuracy and reliability of the experimental results. By adding an appropriate amount of 4-pyridyl ethanesulfonic acid, the pH of the reaction environment can be precisely regulated, creating suitable conditions for biochemical reactions.
In the pharmaceutical and chemical industry, it also plays a key role. On the one hand, it can be used as an intermediate for drug synthesis. In the synthesis path of many drugs, 4-pyridyl ethanesulfonic acid can participate in specific chemical reactions, and through a series of transformations, build the specific structure of drug molecules, and help the development and production of new drugs. On the other hand, in the field of pharmaceutical preparations, its buffering effect can ensure that the chemical properties of drugs are maintained during storage and use, preventing the decomposition or inactivation of drugs due to changes in environmental pH, thereby improving the quality and efficacy of drugs.
In addition, in some industrial production processes, such as the preparation of specific catalysts and the synthesis of fine chemicals, 4-pyridine ethanesulfonic acid also plays a role in promoting the reaction and regulating the direction of the reaction by virtue of its unique chemical properties, which is of great significance for improving product quality and production efficiency.

4-Pyridine ethanesulfonic acid, its physical properties are as follows:
This substance is mostly in the state of white crystalline powder at room temperature, with pure color and fine texture. It has good solubility and can be quickly dissolved in water, just like ice crystals entering a lake, disappearing invisibly and forming a uniform solution. This property makes it convenient to participate in the reaction in many liquid-phase reaction systems.
When it comes to the melting point, it is about a relatively high temperature range. During the heating process, it needs to reach a specific heat, and the lattice structure begins to disintegrate. The molecules break free and gradually change from the solid state to the liquid state. The characteristics of this melting point allow it to maintain a relatively stable solid-state structure under high temperature environments, and it is not easy to melt prematurely.
Its density is also unique. Compared with common organic compounds, it presents a moderate value, which allows it to occupy the right space in the system when participating in the preparation of various preparations, and does not sink due to high density, nor does it float due to too low, ensuring the uniformity and stability of the system.
In addition, the powder of 4-pyridyl ethanesulfonic acid has acceptable fluidity. Although it is not as smooth and unobstructed as fine sand, it can flow more smoothly during normal dumping or transfer, which is convenient for the measurement and transfer process in actual production operations, reducing the inconvenience caused by powder agglomeration or viscosity, and providing many conveniences for industrial production and experimental operations.

4-Pyridine ethanesulfonic acid, this material is special. It is a white crystalline powder with stable properties, mostly stored in the solid state, highly soluble in water, and miscible with many organic solvents.
Looking at its chemistry, it has amphoteric characteristics. The pyridine ring is weakly basic, and can form salts in case of acid; the sulfonic acid group is strongly acidic, and can be ionized in water to produce hydrogen ions, which can neutralize with bases.
Its stability is quite good, and it is not easy to decompose at room temperature and pressure. In case of strong oxidants, strong acids and bases, or chemical reactions. In case of strong oxidants, the pyridine ring or sulfonic acid group is oxidized; in case of strong acids and bases, the ion balance changes, or new compounds are produced. < Br >
4-pyridyl ethanesulfonic acid is widely used in biochemical and pharmaceutical fields. In biochemical research, it is often used as a buffer. Due to its good buffering performance, the specific pH range can stabilize the pH of the solution and protect the activity and structure of biomolecules. In the pharmaceutical industry, or as a pharmaceutical intermediate, with its chemical properties, it can be combined with drugs through a series of reactions.

4-Pyridyl ethane sulfonic acid, if you want to make it, the method is as follows:
Pyridyl and vinyl sulfonate are often used as starting materials. First, pyridyl and an appropriate amount of vinyl sulfonate are mixed in a suitable solvent. If you use a polar organic solvent, such as acetonitrile or N, N-dimethylformamide, these two can make the reactants miscible and create a stable reaction environment.
Next, add an appropriate amount of catalyst, such as a tertiary amine catalyst, such as triethylamine. This catalyst can promote the reaction and increase the reaction rate. The reaction temperature needs to be precisely controlled, generally between 30 ° C and 60 ° C. If the temperature is too low, the reaction will be slow; if the temperature is too high, side reactions will easily occur. In this temperature range, the reaction takes several hours, or several hours, ranging from about 3 to 8 hours, depending on the amount of reactants and the reaction device.
After the reaction is completed, the reaction mixture is obtained. First, the method of reduced pressure distillation is used to remove the solvent to obtain the crude product. After purification by column chromatography, silica gel is selected as the stationary phase, and a suitable eluent, such as ethyl acetate and petroleum ether mixed in a certain proportion, according to the difference in the distribution coefficient between the product and the impurities in the stationary phase and the eluent, so that the product and the impurities are separated, and finally the pure 4-pyridylethane sulfonic acid is obtained. The whole preparation process needs to be operated in a clean, dry and nitrogen stream protected environment to prevent the product from oxidizing or reacting with impurities in the air, resulting in impurity of the product.

The price range of 4-pyridyl ethanesulfonic acid in the market is difficult to determine. Due to the ever-changing market conditions, its price is often influenced by many reasons.
Looking at the changing scene of the market in the past, the quality of materials, the state of supply and demand, changes in manufacturing and regulations of trade and relocation are all major factors affecting its price. If the quality of this product is high and pure, and the supply is thin and there are many people who want it, the price will rise; on the contrary, if the quality is flat and the supply is sufficient, the price may decline.
If the manufacturing process is refined, the cost can be reduced, and the price may also be lowered; and changes in trade and relocation regulations, such as taxes and customs regulations, can also make the price move.
According to the reasons recorded in the "Tiangong Kaiwu" in the past, the price of all things is not static. Therefore, in order to know the exact price of 4-pyridyl ethanesulfonic acid at present, it is necessary to check the recent market conditions in detail, visit merchants, brokers, or check the transaction records to obtain a more accurate number, but it is difficult to give a fixed price range to cope with the ever-changing market.