4-pyridinecarboxylic acid, 3,5-difluoro-

3,2,5-Diene-4-valerynic acid, this is one of the organic compounds. Its main uses are quite extensive, and it has a significant position in the field of organic synthesis.
In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. The conjugated double bond and alkynyl structure of this compound endow it with unique reactivity and spatial configuration. It can build a complex and biologically active molecular skeleton through various chemical reactions, such as nucleophilic addition and cyclization reactions. For example, when developing new drugs for specific diseases, chemists can obtain lead compounds that may have an effect on disease targets by structural modification and derivatization of 3,2,5-diene-4-pentanoic acid, and then lay the foundation for the development of new drugs.
In the field of materials science, 3,2,5-diene-4-pentanoic acid also has its uses. Because of its unsaturated bonds, it can participate in polymerization reactions and prepare polymer materials with special properties. After rational design and synthesis, polymer materials with excellent optical properties, electrical properties or thermal stability can be prepared, which can be used in many aspects such as optoelectronic devices, polymer thin films, etc. For example, copolymerizing it with other monomers may improve the mechanical properties and processing properties of materials and broaden the application range of materials.
In addition, in the total synthesis of natural products, 3,2,5-diene-4-pentyne acid is also often used as an important raw material. Many natural products have complex structures and contain similar structural fragments. By using 3,2,5-diene-4-pentyne acid as a starting material, with the help of a series of precise organic synthesis reactions, the total synthesis of natural products can be realized, which can help in-depth study of the biological activity and pharmacological effects of natural products, and provide strong support for the development of new drugs and the development and utilization of natural product resources.

3,5-Diene-4-valerynic acid is a special organic compound. Its physical properties are as follows:
Viewed, it is mostly liquid or solid at room temperature, which is determined by the intermolecular force and structure. If the intermolecular force is strong, if it contains more polar groups, it tends to be solid; if the intermolecular force is weak, it is more likely to be liquid.
Smell it, or it has a special smell. However, due to the complex structure, the smell is difficult to describe exactly, and the smell perception may be different in different environments.
Measure its melting and boiling point. Because it contains unsaturated bonds and alkynyl groups, its melting point and boiling point are affected by the intermolecular force, relative molecular mass and molecular structure. The unsaturated bond increases, the intermolecular force decreases, and the melting boiling point or decreases; the alkynyl group can enhance the intermolecular force, causing the melting boiling point to increase. The comprehensive results show that the melting boiling point is slightly higher than that of compounds with unsaturated structures.
As for solubility, the compound contains carboxyl groups, has a certain polarity, and has a certain solubility in polar solvents such as alcohols and ethers. However, the hydrocarbyl group part is nonpolar, and it also has a certain solubility in non-polar solvents such as alkanes. The overall solubility is between polar and non-polar solvents.
The physical properties of this compound are of great significance in the fields of organic synthesis and materials science. In organic synthesis, according to its melting boiling point, the separation and purification method can be selected according to its melting boiling point; according to the solubility, the reaction solvent can be selected In materials science, its special physical properties or unique properties, such as improving material flexibility and stability, provide direction for the development of new materials.

The chemical properties of 3% 2C5-diene-4-valyne acid are quite stable. Among these compounds, the molecular structure is unique, and the combination of chemical bonds makes it stable to a certain extent.
From the perspective of its structure, the diene partially interacts with valyne acid to form a relatively stable conjugated system. This conjugated system is like a solid barrier, and the electron cloud distribution is homogenized, thereby enhancing the stability of the molecule. Even if there is a disturbance in the outside world, it takes a considerable amount of energy to break this stable structure.
And its chemical environment has a great impact on the stability. If it is placed in a relatively mild environment without severe chemical reagents or extreme conditions, this compound can maintain its own structure and properties. However, if it is placed in an environment of strong acids, strong bases or strong oxidants, its stability may be challenged. Strong acids and strong bases can react with carboxyl groups or unsaturated bonds, while strong oxidants may oxidize unsaturated bonds, resulting in impaired stability.
But in general, under common chemical environments and general experimental conditions, 3% 2C5-diene-4-valerynic acid exhibits a considerable degree of chemical stability due to its unique molecular structure and conjugate system, and can maintain its own inherent chemical characteristics in many scenarios without easy change.

There are various ways to synthesize 3,5-diene-4-valerynic acid, which you describe in detail below.
First, it can be started from a suitable halogen containing alkynyl and alkenyl groups. Find an alkynyl halogen, the position of the alkynyl group in its structure needs to fit the design of the target molecule, and the halogen atom activity should be moderate. At the same time, finding an alkenyl halogen, the double bond configuration of the alkenyl group and the status of the substituent are all related to the subsequent reaction. Using a strong base as the medium, the nucleophilic substitution reaction of the two occurs. Strong bases such as sodium hydride, potassium tert-butyl alcohol, etc., in suitable organic solvents such as tetrahydrofuran, N, N-dimethylformamide, initiate the reaction of halogenates. In this reaction process, alkynyl negative ions act as nucleophiles, attacking the carbon atoms attached to the halogen atom of the alkenyl halogen, and the halogen atom leaves, thereby forming a carbon-carbon bond, and initially forming an intermediate with an alkynene structure. Later, through an appropriate carboxylation reaction, such as reacting with carbon dioxide under suitable conditions, a carboxyl group can be introduced to obtain 3,5-diene-4-valerynic acid.
Second, it can be started from conjugated alkynyl alcohol compounds. First prepare conjugated alkynyl alcohol, which can be obtained by reacting propargyl alcohol with appropriate alkenylation reagents under the action of metal catalysts. Common metal catalysts such as palladium, copper and other complexes. The choice of alkenylation reagents depends on the structure of the target product. Then, the conjugated alkenyl alcohol is oxidized to the corresponding acid. The oxidation process can be selected as Jones reagent, that is, a sulfuric acid solution of chromium trioxide. Under the conditions of low temperature and moderate stirring, the conversion of alcohol hydroxyl groups to carboxyl groups is achieved, and then 3,5-diene-4-valerynic acid is obtained.
Third, using diethyl malonate derivatives as raw materials is also a feasible method. Diethyl malonate is reacted with halogenated hydrocarbons containing alkynyl groups and alkenyl groups under alkaline conditions, such as alkaline substances such as sodium ethanol. The methylene of diethyl malonate is reacted by alkali to form carbon negative ions, and then nucleophilic substitution occurs with halogenated hydrocarbons. Subsequently, through hydrolysis, decarboxylation and other steps, the protective group is removed and the carboxyl group is constructed. During hydrolysis, acid or base catalysis can be used, and then heat decarboxylation can be used to obtain 3,5-diene-4-valerynic acid.
All methods of synthesis have their own advantages and disadvantages, and they need to be carefully selected according to actual conditions, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.

The price of this chemical product in the market often varies from time to time and place, and the price varies depending on the category. However, to know the market price range of 3,5-diethyl-4-hydroxybenzoic acid, it is still necessary to explore more.
The price of this chemical product may depend on the state of supply and demand, the simplicity of the manufacturing process, and the abundance of raw materials. If you want it in the market, you probably need to visit the commercial premises of chemical materials, or consult the platform for specializing in chemical materials trading.
In today's world, the business conditions are ever-changing, and the price of this product varies according to the market. If you buy it in small quantities, the price per gram may be slightly higher; if you buy it in bulk, the price should be reduced. According to my guess, the price per gram may range from tens of dollars to hundreds of dollars. This is a rough estimate, and the actual price must be consulted in detail from the franchisee. All kinds of prices in the city, such as the situation changes, are not constant. If you want to know the exact number, you must seek it yourself, visit various merchants, and ask them for details before you can get it.