4-Pyridinecarboxylic acid, 2-chloro-6-methyl-

This is 2-chloro-6-methyl-4-pyridinecarboxylic acid, which is a class of organic compounds. Looking at its structure, the 4th position of the pyridine ring is connected with a carboxyl group, and the 2nd and 6th positions are respectively connected with a chlorine atom and a methyl group.
Discussing the physical properties, under normal temperature and pressure, or in a solid state, mostly in a crystalline state, but the specific melting point, boiling point, etc. vary depending on the experimental conditions.
In terms of chemical properties, first, the carboxyl group is acidic and can neutralize with bases to form corresponding carboxylate and water. Second, the pyridine ring is alkaline and can form salts with acids. Third, chlorine atoms are more active, and under suitable conditions, substitution reactions can occur, such as nucleophilic substitution, which is replaced by nucleophilic reagents such as hydroxyl and amino groups. Fourth, methyl groups can participate in oxidation reactions, etc., and can be converted into other functional groups such as carboxyl groups under specific conditions.
In addition, such compounds are widely used in the field of organic synthesis, and can be used as intermediates for the synthesis of many bioactive compounds, which have important potential value in pharmaceutical chemistry, materials science and other fields.

2-Chloro-6-methyl-4-pyridinecarboxylic acid, an organic compound, has important uses in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate. Through specific chemical reactions, it can be converted into compounds with specific biological activities or combined with specific targets, and then used to develop drugs for the treatment of specific diseases. For example, through structural modification and modification, it is expected to develop innovative drugs for certain inflammatory and tumor-related diseases. With its unique chemical structure, it can interfere with the key link in the process of disease occurrence and development.
In the field of materials science, this compound may participate in the construction of new functional materials. Due to its specific molecular structure and chemical properties, it can be integrated into polymer as a structural unit, giving materials such as special optical and electrical properties. For example, in the preparation of some organic optoelectronic materials, adding this compound can optimize the charge transport properties and fluorescence emission characteristics of the material, laying the foundation for the development of new optoelectronic devices.
In the field of organic synthesis chemistry, 2-chloro-6-methyl-4-pyridinecarboxylic acid is an important starting material and can participate in a series of complex organic synthesis reactions. According to its structural characteristics, chemists can use the activities of chlorine atoms, carboxyl groups and methyl groups to construct more complex and diverse organic molecular structures through nucleophilic substitution, esterification, coupling and other reactions, providing a variety of options and possibilities for the development of organic synthetic chemistry, and promoting the creation and research of new organic compounds.

The method for preparing 2-chloro-6-methyl-4-pyridinecarboxylic acid, although not detailed in ancient books, can be based on the principles of modern organic synthesis, and the following method is proposed.
Take 2-methyl pyridine first, which is a readily available raw material. Using chlorine as a halogenating agent, under suitable reaction conditions, the halogenation reaction is carried out. This reaction requires attention to the reaction temperature, reaction time and amount of halogenating agent. If the temperature is too high, it may cause side reactions and cause the product to be impure; if the temperature is too low, the reaction rate will be delayed. Usually, chlorine can be fully reacted with 2-methylpyridine under heating and in the presence of a catalyst, and chlorine atoms are introduced into the 2-position of the pyridine ring to obtain 2-chloro-6-methylpyridine.
Second oxidation reaction of 2-chloro-6-methylpyridine. Strong oxidants such as potassium permanganate can be selected. The oxidation reaction also requires fine regulation of the reaction conditions to ensure the stability of the pyridine ring and the smooth oxidation of methyl groups to carboxyl groups. In this process, the choice of solvent is also very critical. It is necessary to choose a solvent that has good solubility to the reactants and products and does not interfere with the reaction. After oxidation, the crude product of 2-chloro-6-methyl-4-pyridinecarboxylic acid can be obtained.
The crude product still needs to be purified. The method of recrystallization can be used to select a suitable solvent to dissolve the product in a hot solvent, and pure crystals can be precipitated after cooling. Or column chromatography can be used to select suitable stationary and mobile phases for the purpose of separation and purification. After these steps, a relatively pure 2-chloro-6-methyl-4-pyridinecarboxylic acid can be obtained. Although this method is not mentioned in ancient books, today's organic synthesis technology can design a feasible synthesis path based on chemical principles and previous experience.

I don't know the price range of "4 - Pyridinecarboxylic acid, 2 - chloro - 6 - methyl -" in the market. However, "Tiangong Kaiwu" mainly discusses agricultural and handicraft production technology, and does not cover the price of this compound. Information about this compound may be available on the current world chemical product trading platform and chemical raw material suppliers. Or ask senior people and scholars in the chemical industry, who may say the price is approximate based on their experience and market conditions. Or consult chemical market research reports and industry information, which may contain an analysis of the price range of this compound. Unfortunately, when "Tiangong Kaiwu" was located, there was no such thing, and there was no relevant price to test, so if you want to know its price, you should find it in today's market information sources.

2-Chloro-6-methyl-4-pyridinecarboxylic acid is a chemical substance. Its storage conditions are quite important, which is related to the stability and quality of this substance.
This chemical should be stored in a cool place. In a cool place, the temperature is relatively constant, and it will not cause changes in the internal structure of the substance or cause chemical reactions due to high temperature, so as to maintain the stability of its chemical properties. And it must be dry. If the environment is humid, water vapor will easily interact with the substance, or cause it to deliquescent or deteriorate. Therefore, a dry place can protect it from moisture intrusion.
Furthermore, it should be placed in a well-ventilated place. A well-ventilated place can allow harmful gases that may evaporate to dissipate in time without accumulating. It not only ensures that the substance itself is not disturbed by other gases, but also protects the surrounding environment and personal safety.
It is also necessary to pay attention that the container for storing this chemical substance must be well sealed. The seal can prevent air, moisture and other impurities from entering, ensure that the substance is pure and does not react accidentally with external substances.
And because of its certain chemical activity, it should be stored away from fire and heat sources. Fire sources, heat sources or energy supply can cause dangerous reactions such as combustion and explosion of the substance, so it is essential to keep a safe distance.
In summary, 2-chloro-6-methyl-4-pyridinecarboxylic acid should be stored in a cool, dry, well-ventilated place, in a sealed container, and away from fire and heat sources, so that it can be properly stored to ensure the quality and safety of the substance.