4 Pyridinecarboxylic Acid 2 Bromo
pyridine pyrrole pyrazine piperidine piperazine

4-Pyridinecarboxylic acid, 2-bromo-

    Specifications

    HS Code

    907297

    Chemical Formula C6H4BrNO2
    Molar Mass 200.005 g/mol
    Appearance Solid
    Melting Point 157 - 160 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents

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    Frequently Asked Questions

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    What are the chemical properties of 2-bromo-4-pyridinecarboxylic acid?
    2-% heptyl-4-alkynyl butyric acid is an organic compound with unique chemical properties and is of great value in the field of organic synthesis. The following will describe its main chemical properties:
    ** Acidic **: This compound contains a carboxyl group (-COOH), so it is acidic. The hydrogen atoms in the carboxyl group can be partially ionized to release hydrogen ions (H 🥰), which can neutralize with bases. For example, by reacting with sodium hydroxide (NaOH), the corresponding carboxylate and water are formed: 2-heptyl-4-alkynyl butyric acid + NaOH → 2-heptyl-4-sodium alkynyl butyrate + H2O O. This acidity makes it suitable for the preparation of specific carboxylate compounds.
    ** Nucleophilic Substitution Reaction **: The carboxyl group can participate in nucleophilic substitution reactions. For example, under suitable catalysts and conditions, the hydroxyl group (-OH) in the carboxyl group can be replaced by other nucleophilic reagents. Take the esterification reaction with alcohol as an example, under the condition of concentrated sulfuric acid catalysis and heating, it reacts with ethanol to generate 2-heptyl-4-alkynyl butyrate ethyl ester with water: 2-heptyl-4-alkynyl butyrate + C _ H _ OH _ (concentrated sulfuric acid, Delta) 2-heptyl-4-alkynyl butyrate ethyl ester + H _ O. This reaction is an important method for the synthesis of esters, which are often used in the fields of fragrances, solvents, etc.
    ** Reactivity of alkynyl groups **: The alkynyl groups in the molecule (- C ≡ C -) are rich in π electrons and have high reactivity. First, an addition reaction can occur. For example, under the action of a suitable catalyst (such as lindela catalyst), hydrogen (H ²) can be partially hydrogenated to generate compounds containing carbon-carbon double bonds; if a stronger reducing agent and excess hydrogen are used, alkanes can be completely hydrogenated. Second, the alkynyl group can undergo an addition reaction with hydrogen halide (such as HBr), following the Markov rule or anti-Markov rule, depending on the reaction conditions, to form halogenated olefins or halogenated alkanes. Third, the alkynyl group can also participate in some special reactions, such as the trimerization of alkynes. Under the action of specific catalysts, three alkynyl molecules can be polymerized to form aromatic compounds. This reaction can build a special carbon ring structure and has important applications in organic synthesis.
    ** Oxidation Reaction **: The compound may undergo an oxidation reaction. If a strong oxidant is used (such as acidic potassium permanganate solution), both the alkynyl group and the carboxyl group may be oxidized. Alkynyl groups may be oxidized to carboxylic acids, carbon dioxide, etc. It is relatively difficult to further oxidize carboxylic groups, but they may also be destroyed under extreme conditions. Mild oxidants may selectively oxidize alkynyl groups to form carbonyl-containing compounds, providing a way for the synthesis of complex organic molecules.
    What are the common methods for synthesizing 2-bromo-4-pyridinecarboxylic acid?
    Common Synthesis Method of 2-% heptyl-4-allyl butyric acid Dorian method of organic chemistry. The first method can be obtained by reacting a suitable halogenated olefin with a malonate ester compound. First, under the action of a strong base, according to the nucleophilic substitution mechanism, the halogen atom is replaced by the negative ion of the malonate ester to generate the corresponding substitution product. Subsequently, through hydrolysis and decarboxylation, the substitution product of the malonate ester is converted into 2-% heptyl-4-allyl butyric acid. In this process, the choice of a strong base is very critical. The alkalinity of the commonly used strong base such as sodium alcohol needs to be moderate to ensure the smooth progress of the reaction and not cause too many side reactions. The
    method can be synthesized by a reaction involving metal-organic reagents. For example, react with halogenated butyric acid derivatives with suitable alkenyl-based reagents. Ethenyl-based reagents such as alkenyl lithium or alkenyl Grignard reagents have active carbon-metal bonds and can carry out nucleophilic substitution of halogenated butyric acid derivatives. During the reaction, the alkenyl-based reagents are prepared first, and then they are reacted with halogenated butyric acid derivatives in suitable solvents and reaction conditions. This method requires attention to the anhydrous and anaerobic conditions of the reaction system. Because the alkenyl-based reagents are extremely sensitive to water and oxygen, they are prone to reaction and deactivation.
    can be synthesized by the conversion of aldehyde-ketone compounds. First, the aldehyde and ketone compounds are converted into compounds containing alkenyl and carboxyl precursors through suitable reactions, and then further functional group conversion is carried out to generate 2-% heptanobutyric acid. For example, the alkenyl-containing aldehyde and malonic acid can be condensed by Knoevenagel under the action of basic catalysts such as pyridine to generate unsaturated carboxylic acid derivatives containing double bonds. After appropriate reduction or other conversion steps, the target product can be obtained 2-% heptanobutyric acid. In this process, the amount of catalyst and the reaction temperature need to be precisely controlled to achieve the ideal reaction yield and selectivity.
    What fields is 2-bromo-4-pyridinecarboxylic acid used in?
    2-% hydroxy- 4-pentenoic acid, this is an organic compound. It has applications in many fields, as detailed below:
    1. ** Pharmaceutical field **: or can be used as an intermediate for drug synthesis. Due to its structure containing ethylenic bonds and carboxyl groups, these active groups can construct complex drug molecular structures through chemical reactions. For example, through specific reaction steps, it can be converted into compounds with specific pharmacological activities for the development of antibacterial, anti-inflammatory and other drugs.
    2. ** Materials science field **: It can be used to prepare functional polymer materials. It is used as a monomer and introduced into the polymer chain by polymerization to give the material special properties. For example, polymer materials with good biocompatibility and degradability can be prepared for use in tissue engineering scaffolds or drug sustained-release carriers. Because of its ethylene bonds, addition polymerization can occur, and carboxyl groups can also participate in the reaction to adjust the hydrophilicity and reactivity of materials.
    3. ** Fragrance industry field **: With its unique chemical structure, or with a special aroma, it can be used to prepare fragrances. The presence of ethylene bonds and carboxyl groups allows them to be converted into functional groups with different aromas in chemical reactions. After modification and reaction, natural or artificial fragrances can be prepared, adding product aroma characteristics, and applied to perfumes, food fragrances, etc.
    4. ** Organic synthesis field **: As an important organic synthesis intermediate, it participates in various organic reactions and constructs complex organic molecular structures. For example, using carboxylic groups to esterify alcohols, or alkene bonds to participate in electrophilic addition, free radical addition and other reactions, high value-added organic compounds are synthesized, providing a variety of reaction pathways and products for organic synthesis chemistry.
    What is the market price of 2-bromo-4-pyridinecarboxylic acid?
    In today's market, the price of di- and tetraamylbenzoic acid is often affected by various reasons.
    At the end of its raw materials, if its general raw materials, such as di- and tetraamylbenzoic acid, pentanol, benzoic acid, etc., its price will fluctuate due to the lack of land, the lack of harvest, the ease of improvement, or the supply of di- and tetraamylbenzoic acid. For example, if the land of pentanol is difficult every day, the harvest will be low, the supply will be short, and the cost of di- and tetraamylbenzoic acid will be high.
    Furthermore, the cost of manufacturing will also rise. If there is a new technology, it can refine the process, improve efficiency and reduce consumption, and the cost can be reduced, and the market may not be lower. On the contrary, if the labor is low, the energy consumption is huge, and a large amount of labor is required, the cost will be high, and the cost will also decrease.
    The supply and demand of the city also affects its cost. If the demand for ditetraamylbenzoic acid is strong in the market, and the supply is insufficient, the general labor and research needs will be required, and the price will be reduced. On the contrary, if the market demand is weak, the producers will not be able to save, and if they are seeking sales, they must be reduced in order to find a way.
    In addition, external factors such as policy laws and revenue cannot be ignored. If the cost of production increases, the cost of production will increase, and the cost will necessarily be married above the price. And the policy encourages the use of ditetraamylbenzoic acid in a certain field, and the demand may increase, which will push the price up.
    Therefore, in order to know the market of ditetraamylbenzoic acid, the factors of raw materials, industry, supply and demand, and policies can only be approximated. However, the market is instantaneous, and its price is also determined.
    What are the storage conditions for 2-bromo-4-pyridinecarboxylic acid?
    The storage of 2-% arsine-4-pentenoic acid is the most important thing. The nature of this thing may be affected by external factors, so if you want to protect it, you must store it according to the appropriate method.
    2-% arsine-4-pentenoic acid is sensitive to light and water, and it is also easy to produce and melt in the environment of tide. Therefore, the first thing to avoid light is to be placed in the dark, in order to prevent the light from causing it to react and cause it to malfunction.
    Furthermore, it is also a major factor that affects its existence. It should be placed in a cool place, so that the degree is fixed and not high. If the temperature wave is strong or in a high temperature environment, it may cause it to decompose or accelerate its reaction rate, so that it retains its initial properties.
    And because of its dampness or dampness, it is necessary to be dry. If it enters, it may be reversed, or its physical and chemical properties may be changed, so that the thing is not the original.
    Even in the container, it should not be ignored. It is better to make a material with a certain chemical properties and no reaction of 2-% arsenic-4-pentenoic acid. In this way, the side reaction of the container can be eliminated and its survival can be guaranteed.
    Therefore, 2-% arsine-4-pentenoic acid is a suitable container for protection from light, storage, drying, and storage. This is essential for its proper storage. Only by following it can its properties be determined and maintained for a long time.