4 Pyridinecarboxylic Acid 2 Amino 5 Bromo
pyridine pyrrole pyrazine piperidine piperazine

4-pyridinecarboxylic acid, 2-amino-5-bromo-

    Specifications

    HS Code

    861836

    Name 2-amino-5-bromo-4-pyridinecarboxylic acid
    Chemical Formula C6H5BrN2O2
    Molar Mass 217.02 g/mol
    Appearance Solid (appearance may vary)
    Physical State At Room Temp Solid
    Solubility In Water Limited solubility (polar but presence of non - polar parts)
    Solubility In Organic Solvents Soluble in some polar organic solvents
    Acidity Basicity Weakly acidic due to carboxylic acid group
    Pka Of Carboxylic Acid Group Data may vary (depends on environment)
    Stability Stable under normal conditions but can react with strong oxidizing/reducing agents

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    Frequently Asked Questions

    As a leading 4-pyridinecarboxylic acid, 2-amino-5-bromo- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    4-pyridinecarboxylic acid, what are the chemical properties of 2-amino-5-bromo-
    2-Amino-5-bromo-4-pyridinecarboxylic acid, this is an organic compound. Looking at its structure, amino and bromine atoms are connected to pyridinecarboxylic acid, and this structure gives it unique chemical properties.
    Its physical properties are either solid at room temperature, but it may be soluble in polar solvents due to the presence of polar groups. The amino groups in the molecule are basic and can react with acids to form corresponding salts.
    In terms of chemical properties, bromine atoms are highly active and easily participate in nucleophilic substitution reactions. When encountering nucleophiles, bromine atoms may be substituted to form new compounds. This reaction may be used in organic synthesis to construct more complex molecular structures.
    The pyridine ring is an aromatic system, which is aromatic and can participate in many typical reactions of aromatic compounds, such as electrophilic substitution reactions. Under appropriate conditions, the hydrogen atoms on the pyridine ring may be replaced by other groups to enrich the variety of compounds.
    In addition, the carboxyl group is acidic and can react with bases to form salts and water. It can also participate in esterification reactions and form ester compounds with alcohols under the action of catalysts. This is often used in the field of organic synthesis to prepare ester derivatives with specific functions.
    Due to its unique chemical properties, 2-amino-5-bromo-4-pyridinecarboxylic acid may have important uses in the fields of medicinal chemistry and materials science. In drug synthesis, or as a key intermediate, a series of reactions construct drug molecules with specific biological activities; in the field of materials, or because of its special structure, participate in the construction of materials, endowing materials with unique properties.
    4-pyridinecarboxylic acid, what are the main uses of 2-amino-5-bromo-
    4-Pyridinecarboxylic acid, 2-amino-5-bromo-, this substance is widely used. In the field of medicine, due to its unique chemical structure, it may have antibacterial and antiviral effects. Pharmaceutical developers often explore its mechanism of action against specific bacteria, hoping to create new specific drugs and treat patients.
    In the chemical industry, it is often used as a key intermediate in organic synthesis. With its structural activity, it can participate in a variety of chemical reactions to synthesize materials with special properties, such as high-performance plastics, fibers, etc. These materials are widely used in daily necessities and industrial production.
    In the field of materials science, it may contribute to the development of new functional materials. Scientists try to use it as a basis and combine other substances to develop materials with special optical and electrical properties, which can be used in electronic devices, optical instruments and other fields to promote scientific and technological progress.
    And because of its chemical properties, it can be used in the agricultural field to develop new pesticides and plant growth regulators. By accurately acting on specific physiological processes of plants, it helps crops increase production, resist diseases, ensure agricultural harvests, and contribute to people's livelihood and well-being. In short, 4-pyridinecarboxylic acid, 2-amino-5-bromine-have important potential value in many fields, providing many possibilities for the development of various industries.
    4-pyridinecarboxylic acid, what is the synthesis method of 2-amino-5-bromo-
    To prepare 2-amino-5-bromo-4-pyridinecarboxylic acid, the following method can be used.
    First take pyridine as the initial raw material. The nitrogen atom of pyridine is basic and can react with appropriate reagents. Interact with brominating reagents, such as bromine in the presence of suitable catalysts, such as iron powder or iron tribromide, and electrophilic substitution reactions can occur. Pyridine positions 2, 4, and 6 are more susceptible to attack by electrophilic reagents. By controlling the reaction conditions, such as temperature, reagent ratio, and reaction time, the bromine atom can be mainly replaced in position 5 to obtain 5-bromopyridine.
    Then, the carboxyl group is introduced at the 4th position of 5-bromopyridine. The Grignard reagent method can be used to react magnesium with 5-bromopyridine in a suitable solvent such as anhydrous ether to generate Grignard reagent 5-bromopyridine magnesium, which is then passed into carbon dioxide gas. After acid hydrolysis, the carboxyl group can be introduced at the 4th position to obtain 5-bromopyridine carboxylic acid.
    Finally, the amino group is introduced at the 2nd position of 5-bromopyridine carboxylic acid. Diazotization reactions and related transformations can be used. First, a suitable nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, reacts with 5-bromo-4-pyridinecarboxylic acid at a suitable temperature to introduce nitro groups at 2 positions to obtain 2-nitro-5-bromo-4-pyridinecarboxylic acid. Then the nitro group is reduced to an amino group by a reducing agent, such as iron and hydrochloric acid or catalytic hydrogenation, to obtain the target product 2-amino-5-bromo-4-pyridinecarboxylic acid.
    The whole synthesis process needs to pay attention to the precise control of the reaction conditions at each step, such as temperature, pH, reagent dosage, etc., to ensure the smooth progress of the reaction and obtain a higher yield. And after each step of the reaction, suitable separation and purification methods, such as distillation, recrystallization, column chromatography, etc., are required to remove impurities and obtain pure products.
    4-pyridinecarboxylic acid, 2-amino-5-bromo - what is the price range in the market
    I don't know the price of "4 - pyridinecarboxylic acid, 2 - amino - 5 - bromo -" in the market. However, if you want to know its price, you can explore it from many sources.
    If you want to find the price of something in the ancient city, you must visit various merchants. Today, you can also follow this example in the chemical raw material trading market and consult merchants dealing in chemical products. Many chemical trading platforms, such as Gade Chemical Network, have a large number of merchants on them, or there are such things for sale. Looking at the price, you can know the price range.
    Furthermore, consult chemical manufacturers. Manufacturers often have different pricing due to factors such as output and cost. You can write to or call several factories that produce this compound and ask for its wholesale and retail price. A comprehensive comparison can be obtained.
    In addition, academic research institutions may also need this product, and they can ask those who have dealings with it, or know the purchase price range. However, the price of this compound often varies due to quality, purity, market supply and demand, etc. If the purity is extremely high, it is suitable for high-end scientific research, and the price may be expensive; if the market supply is sufficient, the price may become more affordable. If you want to get an accurate price, you must inquire more and compare it in detail to know the price range in the market.
    4-pyridinecarboxylic acid, 2-amino-5-bromo
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