4 Pyridinecarboxaldehyde 2 Bromo 5 Chloro
pyridine pyrrole pyrazine piperidine piperazine

4-Pyridinecarboxaldehyde, 2-bromo-5-chloro-

    Specifications

    HS Code

    830446

    Name 2-bromo-5-chloro-4-pyridinecarboxaldehyde
    Molecular Formula C6H3BrClNO
    Molecular Weight 220.45
    Appearance Solid (predicted)
    Boiling Point 273.7±35.0 °C at 760 mmHg (predicted)
    Melting Point 69 - 73 °C
    Flash Point 119.3±25.9 °C (predicted)
    Density 1.777±0.06 g/cm3 (20 °C, 760 mmHg, predicted)
    Pka -2.51±0.20 (Predicted)
    Solubility Soluble in organic solvents like dichloromethane

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    Frequently Asked Questions

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    4-Pyridinecarboxaldehyde, what are the physical properties of 2-bromo-5-chloro-
    The physical properties of 4-pyridyl-formaldehyde, 2-bromo-5-chlorine are quite impressive. In appearance, this compound often takes a specific form, or is crystalline, or has a certain color, but the exact state needs to be observed experimentally.
    When talking about the melting point, it is an important physical constant. Due to the structural characteristics of the compound, the melting point or a specific temperature range, this range is essential for the identification and purification of the substance. The melting point value can be accurately determined by many experimental measurements, thus providing a key basis for the identification of this substance.
    The boiling point is also its significant physical property. When the external pressure is maintained at the standard state and the compound reaches the boiling point, it changes from liquid to gaseous state. The value of this boiling point reflects the strength of intermolecular forces and is closely related to the stability and volatility of the compound.
    In terms of solubility, it varies in different solvents. In polar solvents, such as water, its solubility may exhibit a certain degree of solubility due to molecular polarity; in non-polar solvents, such as some hydrocarbon solvents, the solubility may be completely different. This solubility characteristic is of great significance in the separation, purification and control of the chemical reaction process.
    In addition, density is also a physical property that cannot be ignored. The determination of the density of this substance is related to the space and mass distribution it occupies in practical applications. Through precise experimental means, its exact density value can be obtained, which provides indispensable data support for the measurement and ratio of materials in the fields of chemical production and material preparation.
    In summary, the physical properties of 4-pyridine formaldehyde and 2-bromo-5-chlorine, from appearance, melting point, boiling point, solubility to density, play a key role in chemical research and practical application, and researchers can further explore their chemical behavior and application potential.
    4-Pyridinecarboxaldehyde, what are the chemical properties of 2-bromo-5-chloro-
    4-Pyridine formaldehyde, 2-bromo-5-chlorine This substance has unique chemical properties. Looking at its structure, bromine and chlorine atoms are connected to specific positions on the pyridine ring, and this structure creates its different chemical properties.
    First of all, the aldehyde group is active and has typical aldehyde reaction characteristics. Oxidation reactions can occur. In case of weak oxidants, such as Torun reagents, it can be oxidized to carboxylic acids. This is the signature reaction of aldehyde groups. Just like the warriors of ancient times, when encountering enemies, they will respond bravely, showing their activity. Under the action of strong oxidants, the degree of oxidation is deeper, and more complex products are formed.
    At the same time, the aldehyde group can be reduced. If a suitable reducing agent is used, the aldehyde group can be reduced to an alcohol hydroxyl group, which is like changing from an offensive state to a defensive state. The property change is very wonderful.
    Furthermore, the bromine and chlorine atoms on the pyridine ring also give it special reactivity. Bromine and chlorine atoms can participate in nucleophilic substitution reactions, just like waiting for a wise man to come and join. When there are suitable nucleophilic reagents, bromine or chlorine atoms can be replaced, thereby introducing new groups and changing the overall properties of the molecule.
    The pyridine ring itself is weakly basic and can react with acids, just like those who can flex and stretch, showing different characteristics in different situations. This alkaline property plays an important role in many chemical reactions, affecting the reaction process and product direction.
    2-Bromo-5-chloro-4-pyridyl formaldehyde, due to its unique structure, combines the characteristics of aldehyde, halogen atom and pyridine ring. It is like a bright pearl in the field of organic synthesis, providing rich possibilities for the preparation of various complex organic compounds, and is an important object of organic chemistry research.
    4-Pyridinecarboxaldehyde, what is the main use of 2-bromo-5-chloro-
    4-Pyridyl formaldehyde, 2-bromo-5-chlorine, has a wide range of uses in today's world. In the field of organic synthesis, it is an essential intermediate. Due to its special structure, it contains aldehyde groups and halogen atoms, which can initiate a variety of chemical reactions. If it is a genus of nucleophilic addition and substitution, it can be used to produce various complex organic compounds, such as those required in the fields of medicine, pesticides, dyes, etc.
    In the creation of medicine, based on this, through delicate reaction design, molecules with specific biological activities can be obtained, which is expected to become a good medicine for treating diseases. For example, it can be reacted with nucleophiles containing nitrogen and oxygen to form new carbon-heteroatom bonds, and derived substances with affinity and action on specific disease targets.
    In the process of pesticide research and development, using its chemical properties, compounds with high insecticidal, bactericidal or herbicidal properties can be synthesized. Its halogen atoms can increase the lipophilic and reactive activity of molecules, and aldehyde groups can participate in the formation of structural fragments that are toxic to pests or pathogens.
    In the dye industry, it can be reacted into dyes with unique colors and properties through a series of reactions. Because its conjugate structure can be chemically modified to adjust the absorption and emission spectra, it can present rich colors and have good dye fastness.
    In conclusion, 4-pyridyl formaldehyde and 2-bromo-5-chlorine provide an important foundation and possibility for the creation of various practical and valuable substances in organic synthesis and related industries due to their unique chemical structures. They are indeed widely used and indispensable chemical raw materials.
    4-Pyridinecarboxaldehyde, what are the synthesis methods of 2-bromo-5-chloro-
    To prepare 2-bromo-5-chloro-4-pyridinal formaldehyde, there are many ways to synthesize it. First, bromine and chlorine atoms can be introduced by halogenation reaction starting from pyridine derivatives. First, under suitable conditions, use an appropriate pyridine compound, under suitable conditions, use a brominating reagent, such as liquid bromine or N-bromosuccinimide (NBS), in a suitable solvent, control the temperature, reaction time and other conditions, so that the bromine atom selectively replaces the hydrogen atom at a specific position on the pyridine ring to obtain a bromine-containing pyridine derivative. Subsequently, chlorine atoms are introduced by chlorination reagents, such as thionyl chloride and phosphorus oxychloride, according to similar reaction conditions and operations. After this halogenation step, a pyridine intermediate containing bromine and chlorine is obtained.
    Then, this intermediate is oxidized to convert the substituent at a specific position on the pyridine ring into an aldehyde group. Usually mild oxidizing agents, such as manganese dioxide and sulfuric acid system, or Dess-Martin reagent, are used in suitable organic solvents to control the reaction conditions and oxidize the intermediate, thereby constructing an aldehyde group on the pyridine ring, and the final target product is 2-bromo-5-chloro-4-pyridine formaldehyde.
    Second, it can also be synthesized from other compounds containing aldehyde groups, bromine atoms, and chlorine atoms through the construction reaction of pyridine rings. For example, the unsaturated aldehyde containing appropriate substituents and nitrogen-containing reagents are cycled to form a pyridine ring in the presence of a suitable catalyst, and the specific position distribution of bromine and chlorine atoms on the pyridine ring is achieved at the same time. This process requires fine regulation of reaction conditions, such as temperature, pressure, reactant ratio, and catalyst dosage, to ensure the accuracy and selectivity of pyridine ring construction, and then to obtain the target product. During the synthesis process, the advantages and disadvantages of each method should be weighed according to actual conditions and needs, and the best one should be chosen to obtain satisfactory yield and purity.
    4-Pyridinecarboxaldehyde, 2-bromo-5-chloro-what are the precautions when storing and transporting
    4-Pyridyl formaldehyde, 2-bromo-5-chlorine This material needs to pay attention to many key matters when storing and transporting.
    It is active and easy to react violently in case of open flame, hot topic or oxidant. Therefore, the storage place must be kept away from the fire and heat source, and it must be stored separately from the oxidant. It must not be mixed in storage to prevent accidents. The warehouse should have good ventilation and heat dissipation conditions and keep it dry, because moisture may affect the quality and even cause dangerous reactions.
    During transportation, the packaging must be tight to ensure that there is no risk of leakage. The transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment, just in case. When driving, follow the specified route to avoid densely populated areas and high temperature environments to prevent danger due to excessive temperature or crowd gathering. When loading and unloading, operators need to be careful to avoid package damage caused by brutal operation.
    Store and transport 4-pyridyl formaldehyde, 2-bromo-5-chlorine, be sure to strictly follow the relevant safety regulations, pay attention to every detail, and ensure the safety of personnel, the environment and the integrity of goods.