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What is the chemical structure of 4- ((pyridine-3-carbonyl) amino acid) butyric acid?
4- ((pyridine-3-carbonyl) amino) butyric acid, its chemical structure is as follows:
The main chain of this compound is a butyric acid structure, that is, a straight-chain fatty acid containing four carbon atoms. At the position of the No. 4 carbon atom of butyric acid, the pyridine-3-carbonyl moiety is connected by an amino group.
The butyric acid moiety is numbered starting from the carboxyl group (-COOH), followed by carbon atoms 1, 2, 3, and 4. On the No. 4 carbon atom, an amino group (-NH -) is connected, and this amino group is in turn connected to the pyridine-3-carbonyl group. Pyridine is a nitrogen-containing six-membered heterocyclic compound with aromatic properties. In the No. 3 position of the pyridine ring (with the nitrogen atom as No. 1, numbered clockwise or counterclockwise), a carbonyl group (-CO -) is connected, and this carbonyl group is connected to the amino group on the No. 4 carbon of butyric acid to form an amide bond (-CONH -).
The whole molecular structure contains not only the part of fatty acid, but also the structural fragment of nitrogen-containing heterocyclic pyridine. This structural feature endows the compound with unique physical and chemical properties, which may have potential applications in organic synthesis, medicinal chemistry and other fields.
What are the main physical properties of 4- ((pyridine-3-carbonyl) amino acid) butyric acid?
4- ((Pyridine-3-carbonyl) amino) butyric acid, this is an organic compound. Its physical properties are quite important and relevant to its application in various scenarios.
Looking at its appearance, it may be a white to off-white solid powder at room temperature and pressure. This color and morphology are quite common in many organic synthetic products, and it is an important guide for identifying and preliminarily judging its purity.
When it comes to melting point, due to the presence of pyridine ring and carboxyl, amino and other groups in the molecular structure, the interaction gives the compound a certain thermal stability. The melting point may be in a specific temperature range, which is of great significance for its crystallization, separation and purification operations. Accurate determination of the melting point can help to determine its purity and identify its structure.
Solubility is also a key physical property. In view of the fact that there are both hydrophobic parts such as pyridine rings and hydrophilic groups such as carboxyl and amino groups in the molecule, its solubility is unique. In organic solvents such as ethanol and dichloromethane, or with a certain solubility, this property makes it possible to choose the reaction medium in organic synthesis. In water, its solubility may be affected by pH value. Under specific acid and base conditions, the degree of ionization of carboxyl groups and amino groups changes, which in turn affects its dissolution in water.
In addition, the density of the compound is also a specific value. This physical quantity is an indispensable parameter in practical operations such as solution preparation and reaction material measurement. Knowing the density can accurately control the relationship between material volume and quality, and ensure that the experiment and production process are accurate.
In short, the physical properties of 4- ((pyridine-3-carbonyl) amino) butyric acid, such as appearance, melting point, solubility, density, etc., are related to each other and affect its application in organic synthesis, drug development and other fields. It plays a fundamental role in further exploring its chemical behavior and practical uses.
In what fields is 4- ((pyridine-3-carbonyl) amino acid) butyric acid used?
4- ((Pyridine-3-carbonyl) amino) butyric acid, which is used in many fields. In the field of medicine, it may be a key intermediate for drug synthesis. Looking at drug development, chemists often create new drugs with specific physiological activities and pharmacological properties by ingenious modification and modification of their chemical structures. Or it can be used to synthesize drugs for specific diseases, such as inflammation, tumors and other diseases. Because of its pyridine ring and aminobutyric acid structural parts, it may endow drugs with unique biological activity and targeting, and can be combined with specific targets in the body to achieve therapeutic purposes.
In the field of materials science, it also has potential applications. It can be used as a basic unit for building special functional materials. Polymer materials with special properties can be prepared by polymerization with other compounds. For example, functional materials that can recognize and adsorb specific substances can be prepared, and they can be used in separation, sensing, etc. This may be due to the specific functional groups contained in their structures, which can interact specifically with the target substances.
In the agricultural field, or can participate in the research and development of new pesticides or plant growth regulators. Because of its unique structure, it may have a positive effect on the growth of crops and pest control. Or it can regulate the growth and development process of plants, enhance the resistance of plants, or show inhibition or killing effects on specific pests and pathogens, and help the sustainable development of agriculture.
In summary, 4- ((pyridine-3-carbonyl) amino) butyric acid has important application potential in the fields of medicine, materials science, agriculture, etc. With the deepening of research, its application prospects may become broader.
What are the synthesis methods of 4- ((pyridine-3-carbonyl) amino acid) butyric acid?
To prepare 4- ((pyridine-3-carbonyl) amino) butyric acid, the following ancient method can be followed.
Take pyridine-3-formyl acid first, and convert it to pyridine-3-formyl chloride with appropriate reagents and reaction conditions. This step requires choosing a suitable chlorination reagent, such as thionyl chloride. At the appropriate temperature and reaction time, the two interact to obtain pyridine-3-formyl chloride.
Take 4-aminobutyric acid at times and mix it with pyridine-3-formyl chloride in a suitable solvent. Commonly used solvents, such as dichloromethane, N, N-dimethylformamide, etc. In this mixed system, it may be necessary to add an appropriate amount of acid binding agent, such as triethylamine, to remove the acid generated by the reaction and promote the forward reaction. After sufficient reaction, the two are combined to obtain 4- ((pyridine-3-carbonyl) amino) butyric acid.
Or another way can be found. First, 4-aminobutyric acid is combined with a protecting group to protect the amino group from its unprovoked participation in subsequent reactions. Commonly used protecting groups, such as tert-butoxycarbonyl (Boc). After protection, 4-aminobutyric acid is reacted with pyridine-3-formyl chloride. After the two are successfully combined, the protective group is removed with suitable reagents and conditions, and the target product 4- ((pyridine-3-carbonyl) amino) butyric acid can also be obtained.
After the reaction is completed, the product or containing impurities should be purified by an appropriate method. The recoverable column chromatography method selects the appropriate eluent to achieve the purpose of separation and purification according to the difference in the distribution coefficient between the product and the impurities in the stationary phase and the mobile phase; it can also use the method of recrystallization to select the appropriate solvent to dissolve the product in the solvent, and then through cooling, concentration and other operations, the product crystallizes and precipitates to obtain pure 4- ((pyridine-3-carbonyl) amino) butyric acid.
What is the market outlook for 4- ((pyridine-3-carbonyl) amino acid) butyric acid?
4- ((Pyridine-3-carbonyl) amino) butyric acid, this product has considerable market prospects at present. It has unique value in the field of pharmaceutical and chemical industry. Guanzhu pharmaceutical research and development may become a key intermediate for new drug synthesis. Due to the combination of pyridine and butyric acid structures, it has special chemical activity and biological activity, which can meet the needs of specific drug targets, and help to create novel and efficient therapeutic agents, which may be beneficial for the treatment of many diseases.
In the chemical industry, it may be an important raw material for the preparation of special materials. With its own structural characteristics, it can participate in reactions such as polymer material synthesis, endowing materials with different properties, such as improving material stability, solubility, etc., and may open up new avenues in the field of high-end material manufacturing.
Furthermore, with the advancement of scientific research and industrial upgrading, the demand for compounds with special structures and functions is on the rise. 4 - ((pyridine-3-carbonyl) amino) butyric acid is expected to emerge in emerging fields due to its unique molecular structure. However, in order to fully tap its market potential, it also faces challenges. Optimization of the synthesis process is the first priority, and efficient and green synthesis methods can reduce costs and increase efficiency and enhance market competitiveness. And it is necessary to deeply explore its physicochemical properties and biological activities to expand the scope of application.
In summary, although 4- ((pyridine-3-carbonyl) amino) butyric acid has broad market prospects, it still needs to cooperate with scientific research and industry to overcome problems in order to show its maximum value.