4-propylpyridine

4-Propylpyridine is also an organic compound. It has a wide range of uses and has important applications in many fields such as chemical industry and medicine.
In the chemical industry, it is often used as an intermediate in organic synthesis. Due to the unique electronic structure and reactivity of the pyridine ring, it can introduce different functional groups through many chemical reactions to prepare various complex organic compounds. For example, it can build the backbone of new compounds through nucleophilic substitution reactions, oxidation reactions, etc., laying the foundation for the synthesis of fine chemicals and materials science related substances.
In the field of medicine, 4-propylpyridine also has important functions. This structural unit will be introduced into the design and synthesis of many drug molecules. Because it can interact with specific targets in organisms and affect biological activities. or participate in the process of drug metabolism, help to improve the efficacy of drugs, improve pharmacokinetic properties, such as enhancing the solubility and stability of drugs, and regulating the absorption, distribution, metabolism and excretion of drugs.
Furthermore, 4-propylpyridine also has potential in materials science. Or can be used to prepare functional materials, such as organic optoelectronic materials. With its structural properties, it may endow materials with unique optical and electrical properties, and be used in Light Emitting Diode, solar cells and other devices, contributing to the development of materials science.

4-Propylpyridine is one of the organic compounds. Its physical properties are quite unique, let me come to you one by one.
Looking at its properties, at room temperature, 4-propylpyridine is mostly colorless to light yellow liquid, with a clear appearance and a special odor. Although this odor is not pungent or intolerable, it is also unique and can be used as a distinguishing feature.
When it comes to boiling point, it has been determined by many experiments that its boiling point is between 195-197 ° C. The boiling point is the temperature limit at which a substance changes from a liquid state to a gaseous state. This boiling point indicates that in order to vaporize it, a considerable amount of heat needs to be applied. This property is of great significance in many chemical operations such as separation and purification.
As for the melting point, the melting point of 4-propylpyridine is about -50 ° C. The level of melting point is related to the transition between solid and liquid states, and the melting point at low temperatures makes the substance stable in a liquid state at room temperature.
In terms of solubility, 4-propylpyridine can be miscible with some organic solvents such as ethanol and ether in any ratio. This is because of the principle of similarity and compatibility, and its molecular structure is similar to these organic solvents, so it can blend with each other. However, its solubility in water is relatively limited, and it is only slightly soluble in water.
In terms of density, the density of 4-propylpyridine is slightly smaller than that of water, about 0.92 g/cm ³. This density characteristic makes 4-propylpyridine mostly float on the water surface when the two are mixed. This phenomenon can also be used for identification and separation in practical applications.
In addition, 4-propylpyridine also has a certain degree of volatility. Although the volatilization rate is not extremely fast, in an exposed environment, after a certain period of time, there will be volatilization losses. This volatility not only affects its storage method, but also requires ventilation conditions in the use environment.
To sum up, the physical properties of 4-propylpyridine, from appearance, melting point, solubility to density and volatility, have their own characteristics. These properties are interrelated and together determine their application in the chemical industry, scientific research and other fields.

4-Propylpyridine, which is an organic compound. Looking at its structure, it contains a pyridine ring and a propyl group. The pyridine ring is aromatic and weakly basic, because it has lone pairs of electrons on the nitrogen atom, which can bind to protons. This property allows 4-propylpyridine to react with acids to form salts. In organic synthesis, it can be used as a base to participate in the reaction and help regulate the pH of the reaction system.
Propyl is attached to the pyridine ring, which also affects its properties. Propyl is an alkyl group, which has an electron-induced effect, which can increase the electron cloud density of the pyridine ring, which in turn affects the reaction activity on the ring. For example, in electrophilic substitution reactions, changes in the electron cloud density can affect the reaction check point and reaction rate. Compared with pyridine, 4-propylpyridine may have a change in electrophilic substitution activity, and substituents may more easily enter the region with higher electron cloud density in the pyridine ring.
4-propylpyridine also has certain solubility. Because it contains hydrophobic propyl and pyridine rings with a certain polarity, it is more soluble in organic solvents or better than pyridine, but its solubility in water is limited. According to this property, the solvent can be reasonably selected in the separation and purification process.
Furthermore, 4-propylpyridine has specific spectral properties due to the vibration and rotation of chemical bonds in the structure. In the infrared spectrum, the vibration of the corresponding chemical bonds between the pyridine ring and the propyl group will produce a characteristic absorption peak, which can be used for structural identification. In NMR spectroscopy, hydrogen atoms in different chemical environments have characteristic chemical shifts, which can confirm their structures. In organic chemistry research and related fields, these spectral properties provide powerful means for the analysis and identification of 4-propylpyridine.

There are several methods for synthesizing 4-propylpyridine. One is to use pyridine as a starting material and alkylate it. Under suitable reaction conditions, pyridine and propylation reagents, such as propyl halides (such as bromopropane), can undergo nucleophilic substitution in the presence of bases. The base can seize the hydrogen atom in the ortho or para-position of the nitrogen atom of pyridine to form a carbonegative ion, which then reacts with the propyl halide to form a carbon-carbon bond, thereby obtaining 4-propylpyridine. In this process, the choice of base is very critical. Common bases such as potassium carbonate and sodium carbonate can be selected according to the specific situation of the reaction. The reaction temperature and time also need to be precisely controlled, usually heated and refluxed for several hours to make the reaction more complete.
The second method can be prepared by the reduction reaction of the corresponding pyridine derivatives. For example, 4-propionylpyridine, by the action of a reducing agent, reduces the carbonyl group to methylene, and then obtains 4-propylpyridine. Commonly used reducing agents such as lithium aluminum hydride, sodium borohydride, etc. However, lithium aluminum hydride has extremely strong reducing properties, and the reaction operation needs to be carried out under severe conditions without water and oxygen; sodium borohydride is relatively mild and the operation is slightly easier.
There are also those who synthesize 4-propylpyridine by coupling reaction catalyzed by transition metals. The coupling reaction between halogenated pyridine and propylboronic acid or its esters occurs under the action of transition metal catalysts (such as palladium catalysts) and ligands. This method has relatively mild conditions and good selectivity. However, the price of transition metal catalysts is often higher, and the cost or factors are considered. The above synthesis methods have their own advantages and disadvantages, and should be selected according to actual needs, such as product purity, cost, reaction conditions, etc.

I don't know the price range of 4-propylpyridine in the market. However, if you want to know its price, you can ask for it in several ways. First, go to the chemical raw material trading platform, which often collects quotes from merchants, and can compare the prices of different sellers to get an approximate price range. Second, ask chemical product suppliers. Many suppliers have professional sales teams, which can answer product prices in detail, and there may be price differences due to factors such as purchase volume and purchase time. Third, looking at industry reports and information, some chemical industry research institutions often publish price trends and market analysis of various products, and here you may get information on the price of 4-propylpyridine. Unfortunately, I have not seen the actual price, so I cannot confirm its price range. However, following these methods, the market price of 4-propylpyridine may be determined.