4-(Phenylcarbamoyl)pyridine

4- (phenylcarbamoyl) pyridine is one of the organic compounds. It has a wide range of uses and is of great value in many fields.
In the field of medicine, this compound may serve as a key raw material for traditional Chinese medicine. After scientific research and practice, its chemical structure and properties may make it show potential therapeutic effects on specific diseases. The research and development of Gain drugs aims to explore bioactive molecules to precisely act on human physiological mechanisms, and 4- (phenylcarbamoyl) pyridine may have this property, which may help to develop new drugs and heal the suffering of patients.
In the field of materials science, it can be used as an important starting material for the synthesis of special materials. By means of organic synthesis, chemists can skillfully combine it with other compounds to create new materials with unique physical and chemical properties. Such new materials may emerge in the fields of electronics and optics, contributing to the development of related industries. For example, they may be used to prepare materials with special photoelectric properties to meet the needs of modern technology for high-performance materials.
Furthermore, in chemical research, 4- (phenylcarbamoyl) pyridine is also often used as an important model compound. By in-depth investigation of its reaction mechanism and chemical properties, scientists can enhance their understanding of the basic theory of organic chemistry and lay a solid foundation for more complex organic synthesis and reaction research. It is like a key that unlocks the treasure house of organic chemistry knowledge and leads researchers to continuously explore unknown chemical fields.
In summary, 4 - (phenylcarbamoyl) pyridine, with its unique chemical structure, plays an indispensable role in medicine, materials science and chemical research, and promotes the progress and development of various fields.

4 - (phenylaminoformyl) pyridine, the physical and chemical properties of this substance are as follows. Its appearance is often white to pale yellow crystalline powder, which is due to the characteristics of its molecular structure. The arrangement and interaction between atoms cause it to appear in this state.
When talking about the melting point, it is between 128 and 132 ° C. This value is derived from the strength of its intermolecular forces, and the interactions between molecules such as van der Waals forces and hydrogen bonds give it a specific melting point range. When the external temperature rises to this range, the molecule obtains enough energy to overcome these forces, thereby transforming from a solid state to a liquid state.
In terms of solubility, it is slightly soluble in water. The hydrogen bond network formed between water molecules is relatively tight, and it is difficult to form an effective interaction between 4- (phenylaminoformyl) pyridine molecules and water molecules to break this network, so it is difficult to dissolve. However, it is soluble in common organic solvents such as ethanol and chloroform. In ethanol, the hydroxyl group can form hydrogen bonds or van der Waals forces with some groups of 4- (phenylaminoformyl) pyridine. In chloroform, the force between its molecule and 4- (phenylaminoformyl) pyridine molecules is sufficient to dissolve it.
Stability, it is relatively stable at room temperature and pressure and in a dry environment. However, in case of high temperature, open flame, or contact with strong oxidants, it is easy to initiate chemical reactions. Because its structure contains carbamyl groups and pyridine rings, these groups have certain reactivity under specific conditions, and are easily oxidized by oxidants or decomposed at high temperatures.

4- (phenylcarbamoyl) pyridine. The synthesis method of this compound has always been exquisite.
First, pyridine-4-carboxylic acid and phenyl isocyanate are used as raw materials. The two are in suitable solvents, such as dichloromethane and toluene. Under mild reaction conditions, such as room temperature to slightly higher temperature, and there is an appropriate amount of catalysts, such as tertiary amines, assisted by nucleophilic addition reaction, the carboxyl group of pyridine-4-carboxylic acid interacts with the isocyanate group of phenyl isocyanate to generate 4- (phenylcarbamoyl) pyridine. The raw materials of this method are relatively easy to obtain, the reaction process is relatively smooth, and the operation is not complicated. < Br >
Second, 4-halopyridine and phenylcarbamate are used as starting materials. In an appropriate organic solvent, such as N, N-dimethylformamide, an appropriate amount of alkali is added, such as potassium carbonate, etc. Under heating conditions, the halogen atom of 4-halopyridine undergoes a nucleophilic substitution reaction with phenylcarbamate, and the halogen atom is replaced by phenylcarbamoyl to obtain the target product. This approach requires attention to the activity of halopyridine and the influence of reaction conditions on the substitution reaction. If the conditions are properly controlled, the yield is also considerable.
Third, the coupling reaction catalyzed by transition metals. For example, pyridine-4-borate and halobenzamide are used as raw materials, and the reaction is carried out in a specific reaction system in the presence of transition metal catalysts such as palladium catalysts. Although this method requires slightly higher reaction conditions and requires precise control of catalyst dosage, ligand selection and reaction temperature, it can achieve more efficient synthesis, especially in situations where product purity and yield are required.
All these synthesis methods have advantages and disadvantages. In practical applications, careful choices need to be made according to factors such as raw material availability, cost considerations, and product purity requirements.

For 4 - (phenylcarbamoyl) pyridine, the market price is not easy to determine. The price of the cover is often changed due to many factors, such as supply and demand, the refinement of the process, the difference in quality, and the rise and fall of the market.
Looking at the state of supply and demand in the past, if there are many seekers and few suppliers, the price will tend to be higher; on the contrary, if the supply exceeds the demand, the price may drop. And the cost of the process of fine, or increase, the price should also be different. The quality of the superior, the price is also different, the pure price is high, the miscellaneous price is low. The rise and fall of the market also has a great impact on the price. In prosperous times, the business is prosperous, and the price may rise steadily and slightly; in troubled times, things are difficult, and the price may fluctuate.
However, although it is difficult to determine the price, according to the business conditions and the same industry in previous years, roughly speaking, the price fluctuates every hundred gold to thousand gold. However, this is only an approximate amount. The actual price must be consulted by various pharmaceutical companies and the current price before it can be accurate. And the market conditions change like the situation, and the price is also new with each passing day. You can't be bound by old news.

4 - (Phenylcarbamoyl) pyridine, when storing and transporting, many things need to be paid attention to.
The first word of storage, this substance should be placed in a cool, dry and well ventilated place. Because it may be sensitive to humidity and temperature, high temperature and humid environment can easily cause its properties to change, or even cause chemical reactions and damage its quality. Keep away from fires and heat sources to prevent accidents. And should be stored separately from oxidants, acids, bases, etc., must not be mixed, because these substances come into contact with it or react violently. In addition, suitable materials should be prepared to contain leaks. If there is a risk of leakage in the storage place, it can be disposed of in time.
As for transportation, it is necessary to ensure that the packaging is intact before transportation. Packaging materials need to have good protective properties and can withstand certain external shocks and environmental influences. During transportation, the speed of the vehicle should be stable, and violent actions such as sudden braking and sharp turns should be avoided to prevent material leakage due to package damage. Transportation vehicles should also be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. And transportation personnel must be professionally trained to be familiar with the characteristics of this substance and emergency treatment methods. At the same time, transportation routes should be planned rationally to avoid densely populated areas and environmentally sensitive areas to prevent leakage from causing significant harm to the public and the environment. In this way, 4 - (phenylcarbamoyl) pyridine is safe during storage and transportation.