4-Phenyl-1,2,3,6-Tetrahydropyridine

4-Phenyl-1,2,3,6-tetrahydropyridine has a wide range of uses. In the field of pharmaceutical and chemical engineering, it is often used as a key intermediate in the creation of many drugs. Due to its unique chemical activity and spatial configuration, it can be modified by various chemical reactions to construct complex and diverse molecular structures with specific biological activities. For example, in the synthesis of drugs for the treatment of some neurological diseases, the structural unit of 4-phenyl-1,2,3,6-tetrahydropyridine can precisely regulate the interaction between drugs and neural receptors, enhance drug efficacy and reduce adverse reactions.
In the field of materials science, it also has extraordinary performance. It can participate in the preparation of specific functional materials, such as some optoelectronic materials. Due to the unique electron cloud distribution and conjugate system endowed by its molecular structure, the material exhibits excellent properties in light absorption, emission and charge transport, which opens up a new way for the research and development of new optoelectronic materials.
In organic synthetic chemistry, 4-phenyl-1,2,3,6-tetrahydropyridine, as an important synthetic block, can rely on rich reaction check points, through nucleophilic substitution, addition and other reactions, combined with many organic reagents to construct complex and diverse organic compounds, which greatly promotes the development and innovation of organic synthetic chemistry.

4-Phenyl-1,2,3,6-tetrahydropyridine, its physical properties are as follows. This substance is mostly liquid at room temperature, and it has a certain fluidity, like the water of a stream, flowing naturally. Its color is often nearly colorless, clear like a clear spring in the mountains, without the disturbance of variegated colors.
Smell it, the smell is unique, although it is not pungent and unpleasant like a rancid thing, it also has its own smell, which is difficult to describe exactly. It is like a strange fragrance hidden in a deep forest valley. At first, it is unfamiliar when smelled, and the fine taste has a different charm.
When it comes to density, it is slightly lighter than water. If you take water as a reference and put it into water, it is like a light boat floating on the lake surface, floating on the water, and does not blend with the water, and each is a state.
In terms of solubility, in organic solvents, such as ethanol, ether, etc., it has quite good solubility, just like salt melting in water, it can be integrated with it to form a uniform state; however, in water, the solubility is poor, and the two meet, like oil and water, distinct and difficult to integrate.
Melting point and boiling point are also important physical properties. The melting point is low, and it melts when it warms up a little, just like thin ice in winter when it meets the warm sun, which is easy to melt and invisible; the boiling point is relatively high, and more heat needs to be applied to make it turn from liquid to gaseous, just like cooking oil on fire. It needs to be heated in place to see changes.
In addition, its refractive index also has a specific value. When light passes through, the light path is deflected and has a unique performance, just like light traveling through a fantasy crystal, showing different optical properties. This is also the physical properties of 4-phenyl-1,2,3,6-tetrahydropyridine.

The chemical synthesis of 4-phenyl-1,2,3,6-tetrahydropyridine is a very important topic in the field of organic synthesis. Although the method of synthesis of this compound is not detailed in the ancient book "Tiangong Kaizi", the methods of organic synthesis at present can be as follows.
Usually phenethylamine and acrylic aldehyde are used as starting materials. First, the Mannich reaction of phenethylamine and acrylic aldehyde should be carried out. The reaction conditions should be mild. In a suitable solvent, such as ethanol or dichloromethane, an appropriate amount of acid catalyst, such as acetic acid or p-toluenesulfonic acid, is added, and heated to a moderate temperature, such as 50-80 ° C. The two are heated to a critical intermediate through nucleophilic addition steps. The intermediate formed by
is then cyclized, and an appropriate base, such as potassium carbonate or sodium carbonate, is heated in a suitable solvent to promote cyclization to construct the ring structure of tetrahydropyridine. This step requires attention to the control of reaction time and temperature. If the temperature is too high or the time is too long, it may cause side reactions to occur, which will affect the purity and yield of the product.
Another is synthesized by Diels-Alder reaction using styrene and 1,3-butadiene as raw materials. The reaction is carried out under the protection of inert gas and under appropriate temperature and pressure conditions with suitable catalysts, such as certain metal complexes. The Diels-Alder reaction has good regioselectivity and stereoselectivity, which can efficiently construct the basic skeleton of the target molecule. After appropriate functional group transformation, 4-phenyl-1,2,3,6-tetrahydropyridine can be obtained.
During the synthesis of this compound, precise control of reaction conditions, purity requirements of raw materials, and separation and purification of intermediate products are essential, so that high purity and high yield of 4-phenyl-1,2,3,6-tetrahydropyridine can be obtained.

I don't know the price range of 4-phenyl-1,2,3,6-tetrahydropyridine on the market. However, if you want to know its price, you can explore it from various sources.
First, if you are in a specialized market for chemical raw materials trading, you can ask various firms, who are engaged in such chemicals, or you can know their current prices. This is the way of on-the-spot inquiry, which can directly obtain the quotation of the firm, and may be able to find out the price difference due to the quantity.
Second, search for the name of this product on the online chemical product trading platform. On the platform, there are many merchants listing prices, and you can also look at the prices of past transactions, and you can compare the prices of different merchants to know the approximate price range. Or you can check industry reports, which often include information such as market price trends and current average prices, which can help clarify their price ranges.
However, due to factors such as raw material costs, supply and demand conditions, and production process difficulties, the price is not constant. Therefore, in order to obtain accurate prices, it is necessary to rely on real-time inquiries and multi-party inquiries.

4-Phenyl-1,2,3,6-tetrahydropyridine is also an organic compound. Its storage conditions are related to the stability and safety of its properties and must not be ignored.
This compound should be placed in a cool and ventilated place. Because of the cool place, it can avoid the disturbance of high temperature. High temperature can easily intensify the movement of compound molecules, or cause chemical reactions, damage its purity, or even cause danger. A well-ventilated place can disperse harmful gases that may escape in time and preserve the safety of the storage environment.
and must be kept away from fire and heat sources. Both fire and heat sources can provide energy, greatly increase the reactivity of the compound, or cause disasters such as combustion and explosion. In its warehouse, all electrical equipment and lighting devices should be explosion-proof to prevent electrical sparks from causing accidents.
Furthermore, it should be stored separately from oxidizing agents, acids and other substances. Oxidizing agents are strongly oxidizing, acids or corrosive, and coexist with 4-phenyl-1,2,3,6-tetrahydropyridine, which can easily induce chemical reactions, cause deterioration, and increase safety risks. When storing, all kinds of substances are clearly divided, marked and eye-catching, easy to manage and access, and can prevent misuse.
Packaging is also crucial. Make sure the packaging is complete and sealed. Complete packaging can block the intrusion of external air, moisture and other factors, and protect compounds from its influence. A good seal can prevent the compound from volatilizing and escaping, which not only guarantees its quality, but also protects the environment and personal safety. During storage, regular inspections should be made to see if the packaging is damaged and whether the environmental conditions are suitable. If there is any abnormality, immediate disposal can ensure the safety and stability of 4-phenyl-1,2,3,6-tetrahydropyridine storage.