4-(N-Phenylcarbamoyl)pyridine

4- (N-phenylcarbamoyl) pyridine is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, assisting pharmaceutical chemists in the design and development of compounds with specific pharmacological activities, such as anti-cancer, antibacterial, anti-inflammatory and other drugs. For example, by modifying and modifying its structure, it can optimize the pharmacokinetic properties of drugs, improve efficacy and reduce side effects.
In the field of materials science, it also has significant functions. Can participate in the preparation of polymer materials with special properties. Due to the functional groups of the compound, it can endow the material with specific physical and chemical properties, such as improving the thermal stability, mechanical properties and optical properties of the material. These materials may be used in the manufacture of electronic devices, optical instruments and high-performance engineering plastics.
Furthermore, in the field of organic synthesis chemistry, 4- (N-phenylcarbamoyl) pyridine is often used as a reaction substrate or catalyst to participate in a variety of organic reactions. With its unique reactivity, it can realize the construction of complex organic molecules, promote the development of organic synthesis methodologies, and provide an effective way for the synthesis of organic compounds with novel structures.
In conclusion, 4- (N-phenylcarbamoyl) pyridine plays an important role in many fields such as medicine, materials and organic synthesis due to its own structural characteristics, and has made great contributions to the progress of related science and technology.

4- (N-phenylcarbamoyl) pyridine is one of the organic compounds. Its physical properties are worth exploring.
In terms of its appearance, it is often white to light yellow crystalline powder, delicate and shiny, just like a treasure of the sky. Its properties are stable at room temperature and pressure. If the ambient temperature and pressure change abruptly, its physical state may change slightly.
Looking at its melting point, it is about a specific temperature range. This temperature is the boundary point where the balance of forces between molecules is broken and the lattice structure is disintegrated. When heated to this point, the substance gradually melts from a solid state, like ice and snow when warmed, and transforms into a liquid state, showing the wonderful transformation of the state of matter.
Solubility is also an important property. In common organic solvents, such as ethanol, acetone, etc., or with a certain solubility. The polarity of ethanol is consistent with the partial structure of the compound, and it can be attracted by intermolecular forces to disperse it in the ethanol system, just like a fish swimming in water, free and melted; however, in water, its solubility may be limited, because the polarity of water is different from the overall polarity matching of the compound, it is difficult to form a good interaction.
Its density also has a specific value, reflecting the degree of tight packing of molecules. The density is established, and its unit volume mass can be known. This is of great significance in many practical application scenarios, which is related to the space and weight distribution of substances in the system.
In addition, the volatility of this compound is very small. Under normal conditions, the tendency of molecules to escape to the gas phase is low, and it can maintain the aggregate state of solid or liquid for a long time. It is like a stable person, sticking to the standard and not changing easily.
In summary, the physical properties of 4- (N-phenylcarbamoyl) pyridine are diverse and unique, laying the foundation for its application in chemistry, materials and other fields.

To prepare 4- (N-phenylcarbamoyl) pyridine, the following ancient method can be used.
First, pyridine-4-carboxylic acid is used as the starting material, and it is co-placed with dichlorosulfoxide in a round bottom flask, and slowly heated until refluxed. After about an hour, pyridine-4-carboxylic acid reacts fully with dichlorosulfoxide, and the carboxyl group of pyridine-4-carboxylic acid is converted into an acyl chloride group to obtain pyridine-4-carboxylic chloride. This step of reaction needs to be done carefully in the fume hood, because dichlorosulfoxide is highly corrosive and irritating. < Br >
Take the prepared pyridine-4-formyl chloride for the second time, and after cooling, slowly drop it into an organic solvent containing aniline, such as toluene. Stir when dropping, and keep the temperature under control in an ice bath to prevent overreaction. After dripping, remove the ice bath and stir at room temperature for several hours. The nucleophilic substitution reaction between the amino group of aniline and the acyl chloride group of pyridine-4-formyl chloride results in a crude product of 4- (N-phenylaminoformyl) pyridine. In this step, the choice of organic solvent is very critical. Those with good solubility of the reactants and no side reactions with the reactants and products should be selected.
The crude product is purified after. First wash with dilute acid solution to remove unreacted aniline and its hydrochloride impurities. Then wash with saturated saline water to reduce the solubility of the product in the aqueous phase and reduce the loss. Then dry the organic phase with anhydrous sodium sulfate to remove the moisture. Finally, further purification is performed by reduced pressure distillation or column chromatography to obtain pure 4- (N-phenylcarbamoyl) pyridine. Vacuum distillation requires precise temperature and pressure control, and column chromatography requires appropriate stationary and mobile phases to achieve good separation effect.

I haven't heard of the price of "4- (N - Phenylcarbamoyl) pyridine" in the market. However, if you want to know the market price of this product, you should investigate it in detail in various cities.
In the city of chemical raw materials, or there is a trade name specializing in these chemical agents. You can send someone to the other place and ask the shopkeeper, who may know the current price of this product. Or on the online business platform, if there is a field where chemical products are sold, search for their name, and look at the price marked by each merchant to know the price range.
Furthermore, the price of this chemical may vary depending on quality, purity, origin, supply and demand. If its purity is high, it is directly supplied from the place of origin, and the market needs more and less, the price is high; conversely, if the purity is slightly lower, the place of origin is far away and the transportation is inconvenient, and the supply is more than the demand, the price is low.
However, it is difficult for me to determine the range of its price. I only hope that you can obtain its exact price by following the above method and visiting in person.

4- (N-phenylcarbamoyl) pyridine is one of the organic compounds. Its storage is essential to the stability and safety of this compound.
This compound should be placed in a cool and dry place. If it is cool, avoid baking at high temperature, because high temperature often promotes its chemical reaction, causing it to decompose or deteriorate. In a dry place, moisture can be prevented. Moisture encounters with the compound, or reacts such as hydrolysis, which damages its purity and properties.
Furthermore, this compound must be placed in a well-ventilated place. Good ventilation can dissipate harmful gases that may be generated, and reduce the risk of explosion and fire. If harmful gases accumulate, they are prone to accidents in case of open flames or energy sources. < Br >
When storing, the container must be sealed. Good sealing can prevent the invasion of air, moisture and other impurities. The air contains oxygen, carbon dioxide, etc., or reacts with compounds such as oxidation, and carbon dioxide may cause its pH to change.
In addition, the storage place should be far away from fire sources, heat sources and strong oxidants. Fire sources and heat sources can easily raise the temperature of compounds and increase their reactivity. Strong oxidants are highly oxidizing, and when they encounter compounds, they may cause severe oxidation-reduction reactions, generate heat, gas, cause container rupture, or even explode.
In the storage place, when clearly marked, show the name of the compound, properties, hazards and emergency measures. In this way, when people come into contact, they can quickly understand the situation and prevent misoperation and risk. During handling and storage, handle with care to avoid damage to the container and ensure the integrity and safety of the compound.