4-(N,N-Dibutylamino)pyridine

(N, N-docosyl dimethyl tertiary amine) its main use, "Tiangong Kaiwu" said: "Where (N, N-docosyl dimethyl tertiary amine) is an important chemical substance. Its use is multi-terminal, in the field of daily chemicals, can make surfactants. This agent can lower the surface tension of liquid, make water and oil soluble, in detergents, the decontamination power is quite strong, can remove oil stains, make the material clean."
In the textile printing and dyeing industry, (N, N-docosyl dimethyl tertiary amine) can be used as a leveling agent. When the fabric is dyed, the dyes are evenly dispersed, the color of the cloth is uniform, and there is no difference in depth. The quality is quite good.
Furthermore, in oil extraction, it is also useful. It can be used as a corrosion inhibitor to protect metal instruments in the oil production process, prevent them from being eroded and rusting and rotting, ensure the durability of the equipment, and make oil production smooth.
In the paper industry, (N, N-docosyl dimethyl tertiary amine) can be a softener. Paper is treated with it, which is soft to the touch and improves the texture. It is suitable for household paper, etc., to increase its comfort.
In short, (N, N-docosyl dimethyl tertiary amine) is widely used and plays an important role in many industries. It is indispensable for industrial production.

4- (N, N -diethylamino) pyridine is a commonly used catalyst in organic synthesis. It has the following physical properties:
In appearance, it is usually colorless to pale yellow crystalline powder. Under normal light and environment, it presents this stable color state, which is convenient for observing its state in various reaction systems.
The melting point is about 57-60 ° C. This melting point makes it easy to melt into a liquid state under appropriate heating conditions, which is conducive to uniform dispersion in the reaction system and promotes the reaction. The boiling point of
is 211-212 ° C, a relatively high boiling point, which means that in the general organic reaction temperature range, it exists stably in liquid or solid state, and it is not easy to evaporate a lot due to temperature increase, ensuring that the concentration of the catalyst in the reaction system is relatively stable.
In terms of solubility, it is soluble in common organic solvents, such as ethanol, chloroform, benzene, etc. This good solubility allows it to be fully mixed with many organic reactants to form a homogeneous reaction system, which greatly improves the reaction efficiency and selectivity. And slightly soluble in water, this different solubility to water and organic solvents provides convenience for its separation and purification after the reaction. It can be effectively separated from the reaction products by means of aqueous-organic phase separation. In addition, 4- (N, N-diethylamino) pyridine is weakly basic, and the lone pair electrons on its nitrogen atom can bind to protons. It can participate in the reaction as a base in organic reactions, promoting nucleophilic substitution, esterification and other reaction processes, which is of great significance to the development of organic synthetic chemistry.

4- (N, N -diethylamino) pyridine is an organic compound with unique chemical properties. This substance has a wide range of uses in the field of organic synthesis, often acting as a catalyst and playing a significant role.
Its chemical properties are weakly basic due to the nitrogen heterocycle and diethylamino group. This basic property enables it to react with acids to form corresponding salts. And the lone pair electrons on its nitrogen atom can participate in the coordination and form complexes with metal ions, etc. This property is of great significance in catalytic reactions.
In organic synthesis, 4- (N, N -diethylamino) pyridine exhibits high catalytic activity. In the esterification reaction, the reaction rate can be increased, making it easier for carboxylic acids and alcohols to form ester products. In many reaction types such as nucleophilic substitution reactions, it can also effectively promote the reaction by virtue of its alkalinity and electronic effects, helping to construct the structure of various organic compounds.
In addition, its stability is relatively good, under common reaction conditions, it can maintain its own structure and continue to play a catalytic function. However, when using, it is still necessary to pay attention to the pH, temperature and other factors of the reaction system, because these conditions may affect its catalytic performance. In summary, 4 - (N, N - diethylamino) pyridine occupies an important position in the field of organic synthesis chemistry due to its unique chemical properties, providing a key boost for the preparation of many organic compounds.

(N, N-diisopropyl ethylamine) is widely used in synthesis.
First, in the field of organic synthesis, it is often used as a base. Due to its moderate alkalinity and steric resistance, it can effectively promote many nucleophilic substitution reactions and elimination reactions. For example, in the reaction between halogenated hydrocarbons and nucleophiles, it can help nucleophiles to more easily attack the carbon atoms of halogenated hydrocarbons and promote the smooth progress of the reaction. Like the reaction between alcohol and halogenated hydrocarbons to form ethers, N, N-diisopropyl ethylamine can capture the hydrogen of alcohol hydroxyl groups, enhance the nucleophilicity of alcohol negative ions, and then increase the yield of ethers.
Second, it also plays a key role in drug synthesis. In peptide synthesis, it can neutralize the acid produced by the reaction, maintain a suitable reaction environment, and ensure the smooth growth of peptide chains. And because of its alkalinity, it can form salts with some acidic intermediates, improve the stability and solubility of intermediates, and facilitate subsequent reaction operations.
Third, in some reactions that require mild alkaline conditions, its advantages are prominent. Compared with strong bases, it will not cause overreaction or side reactions of substrates. For example, when some base-sensitive compounds are functionally converted, N, N-diisopropyl ethylamine can not only provide the required alkalinity, but also avoid substrate damage, so as to accurately achieve the synthesis of the target product.
In conclusion, N, N-diisopropyl ethylamine is indispensable in many fields such as organic synthesis and drug synthesis due to its unique chemical properties. It is of great significance for the smooth development of synthesis reactions and the efficient acquisition of target products.

To prepare 4- (N, N -diethylamino) medicine, there are various methods.
First, the corresponding halogenated hydrocarbons and diethylamine can be replaced by nucleophilic methods. Take an appropriate amount of halogenated hydrocarbons, place them in a clean reactor, use alcohol as a solvent, add diethylamine, and then add an appropriate amount of alkali, such as potassium carbonate, to promote the reaction. When heated to a suitable temperature, usually 50-80 degrees Celsius, when stirring the number of reactions, observe it closely during the period. After the reaction is completed, the product can be obtained by extraction, distillation, etc. This is a classic method. However, halogenated hydrocarbons may be toxic and corrosive, and the operation should be careful. < Br >
Second, the method of reducing the amination of aldehyde or ketone and diethylamine. First, the aldehyde or ketone and diethylamine are reacted in an appropriate amount of catalyst, such as p-toluenesulfonic acid, in an alcohol solvent to form an imine intermediate. Then a reducing agent, such as sodium borohydride, is added slowly at low temperature to maintain the stability of the reaction system. After the reaction, it is separated and purified to obtain the target product. This method has mild conditions and good selectivity, but the price of the reducing agent is higher and the cost increases.
Third, the corresponding carboxylic acid derivative is reacted with diethylamine. If it is an acid chloride, it is slowly dropped into an organic solvent containing diethylamine, reacted at low temperature, and then processed to obtain the product. If it is an acid anhydride, it also needs to be reacted with diethylamine under suitable conditions. This way, the raw material is easy to prepare, but the activity of acid chloride is high, and the operation needs to avoid water and air, and there are many side reactions.
All production methods have their own advantages and disadvantages. In actual preparation, when considering the availability of raw materials, cost, product purity and many other factors, choose.