4-methoxypyridine-3-carboxaldehyde

4-Aminoethoxyethylene-3-butenonitrile, this is an organic compound. Its chemical properties are unique and valuable for investigation.
In this compound, the presence of amino groups endows it with certain alkalinity. The nitrogen atom in the amino group has a lone pair of electrons, which can be combined with protons. In an acidic environment, it is prone to protonation reactions to generate positively charged ions. At the same time, amino groups can also participate in many nucleophilic reactions, because the lone pair of electrons of nitrogen atoms can be used as nucleophilic reagents to attack electrophilic centers such as carbonyl carbons, and then substitution and addition reactions occur.
The ethoxy part has an impact on the distribution of molecular electron clouds due to the electronegativity of oxygen atoms. The ethoxy group is an electron donor group, which can increase the electron cloud density of the carbon atoms connected to it, which affects the reactivity and stability of the molecule. And the carbon-oxygen bond in the ethoxy group has a certain polarity, and under certain conditions, it can break and participate in chemical reactions.
Ethylene structure is rich in electrons and has high reactivity. Carbon-carbon double bonds can undergo addition reactions, such as addition with halogens, hydrogen halides, water and other reagents, and the double bonds open to form new compounds. It can also participate in oxidation reactions. Under the action of appropriate oxidizing agents, it can be oxidized to different oxidation products such as diols, aldodes, and ketones.
The nitrile group in butene nitrile has active chemical properties. Nitrile groups can undergo hydrolysis reactions, and under the catalysis of acids or bases, they can be gradually hydrolyzed into amides, thereby forming carboxylic acids. Nitrile groups can also participate in nucleophilic addition reactions, reacting with compounds containing active hydrogen, such as alcohols and amines, to form new nitrogen-containing or oxygen-containing derivatives.
This compound is rich in chemical properties due to the coexistence of a variety of functional groups, and the interaction of each functional group makes it rich and diverse. It can be used as an important intermediate in the field of organic synthesis to construct more complex organic molecular structures.

The synthesis method of 3-methylpentyne is often as follows:
First, the inverse of alkylene replacement. Using acetylene instead of ethane as the starting material, under the action of an amino group such as an amino group ($NaNH_2 $), acetylene first forms acetylene. This is because of the inverse nature of the amino group, which can remove the ethylene from the acetylene molecule to form acetylene. The acetylene is nuclear, and the acetylene is nuclear, which can be replaced by ethane in one step. Ethoxy replaces the atom to generate 3-methylpentyne. The inverse formula can be expressed as: $HC\ equiv CH + NaNH_2\ longrightarrow HC\ equiv CNa + NH_3 $, $HC\ equiv CNa + CH_3CH_2Br\ longrightarrow CH_3CH_2C\ equiv CH + NaBr $.
Second, synthesized from carbonyl compounds. With a starting material of 2-pentanone, the enol of the first phase of 2-pentanone is reduced to 2-pentanone. This step can be achieved by treating 2-pentanone with an alcohol such as alcohol. Enol is formed, and then methane is reversed. The atom in methane is attacked by the oxygen atom of the enol, and the nucleus of the enol substitutes for the inverse to generate an enol ether containing methyl substitution. The enol ether rearranges and rearranges under acidic conditions to produce 3-methylpentyne. The approximate reverse path is: $CH_3COCH_2CH_2CH_3 + NaOEt\ longrightarrow CH_3C (O ^ - ) = CHCH_2CH_3 + EtOH $, $CH_3C (O ^ - ) = CHCH_2CH_3 + CH_3I\ longrightarrow CH_3C (OCH_3) = CHCH_2CH_3 + NaI $, $CH_3C (OCH_3) = CHCH_2CH_3\ xrightarrow {H ^ +} CH_3CH_2C\ equiv CH + CH_3OH $.
Third, the addition of alkynyl is reversed. With 1-pentyne feedstock, in the presence of catalysts such as mercury-containing catalysts, methylation of 1-pentyne is generated such as methyl Grignard ($CH_3MgBr $). The methylcarbon part of the methyl Grignard is nuclear, and it is used to attack the alkyne trioxide of 1-pentyne to generate nucleus addition to generate 3-methylpentyne. The reverse formula can be written as: $CH_3CH_2CH_2C\ equiv CH + CH_3MgBr\ xrightarrow {catalytic} CH_3CH_2C\ equiv CCH_3 + MgBr (OH) $ (In the reverse, Grignard's water-containing active compounds such as water are hydrolyzed, which is schematic).

4-Aminopyridine-3-formonitrile is an important organic compound that has significant uses in many fields.
In the field of medicinal chemistry, it has a wide range of uses. It can be used as an intermediate in drug synthesis to prepare drugs with specific physiological activities. Due to its unique structure, the characteristics of nitrogen-containing heterocyclic and cyanyl groups endow it with the potential to interact with biological macromolecules. For example, it can be introduced into the molecular structure of drugs through a series of chemical transformations to enhance the binding force between drugs and targets, improve the efficacy and selectivity of drugs, and may be of great value in the development of drugs for the treatment of nervous system diseases, cardiovascular diseases, etc.
In the field of materials science, 4-aminopyridine-3-formonitrile is also useful. It can participate in the preparation of functional polymer materials. By polymerizing with other monomers, its special structure is introduced into the polymer chain, so that the material has unique electrical, optical or mechanical properties. When preparing conductive polymer materials, the compound can adjust the electronic transport properties of the material and is expected to be applied to organic electronic devices, such as organic Light Emitting Diodes, field effect transistors, etc.
In the field of organic synthetic chemistry, this compound is an important synthetic building block. Because both cyano and amino groups are active reaction check points, they can participate in many classical organic reactions, such as nucleophilic substitution, addition reactions, etc., providing an effective way to construct complex organic molecular structures. Organic chemists can use it as a starting material to design reaction routes to synthesize a series of organic compounds with diverse structures, enriching the research content and results of organic synthetic chemistry.
In short, 4-aminopyridine-3-formonitrile has shown important application value in many fields such as medicine, materials and organic synthesis due to its unique structure. With the deepening of scientific research, its potential uses may be further expanded and explored.

In today's market, the price of 4-methoxypyridine-3-formaldehyde varies according to quality, quantity and market conditions. If it is of high quality, the price may be slightly higher; if it is purchased in bulk, the price may be reduced.
Taste the business saying: "The price of goods is derived from supply and demand, and it is shaped by market conditions." The market's demand is prosperous, and its price tends to rise; if supply exceeds demand, the price tends to fall. These two are always important for the city to weigh.
In today's market of 4-methoxypyridine-3-formaldehyde, if factories compete to purchase it for pharmaceutical and chemical needs, its price will rise. And if the extraction of raw materials is difficult and the labor cost increases, the price will also increase.
On the contrary, if the market demands less and the factory has a lot of goods, it is necessary to sell and take off the goods quickly. Merchants may reduce prices to promote trade. And the same industry competes in the market, often based on price as the blade, competing for shares, and the price drops accordingly.
As for the exact value, it is difficult to say. Or a few yuan per gram, or tens of yuan, all vary according to time, place, quality and quantity. To know the details, you must consult pharmaceutical dealers, chemical brokers, or visit various cities to get a near-real price.

3-Methyl ether needs to be stored in a low temperature and ventilated place, away from fire and heat sources. Its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of open flame and high heat energy. Therefore, it should be stored separately from oxidants, acids and halogens, and mixed storage should not be avoided.
3-Methyl ether is highly volatile and is a colorless flammable liquid at room temperature and pressure. Its vapor is heavier than air and can spread to a considerable distance at a lower place. In case of fire, it will catch fire and backfire. Therefore, the storage environment needs to be well ventilated to prevent vapor from accumulating and forming an explosive environment.
In addition, the storage container should be well sealed, and explosion-proof lighting and ventilation facilities should be used. It is forbidden to use machinery and tools that are prone to sparks. When handling, it should be handled lightly to prevent damage to packaging and containers. Improper storage may not only cause changes in the properties of 3-methyl ether itself, but also affect its use, and may cause serious safety accidents, threatening the safety of people and property.