4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitril

4-Methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile, an organic compound. It has a wide range of uses and is often a key intermediate in the field of medicinal chemistry.
In the process of drug synthesis, it can be converted into compounds with specific biological activities through clever chemical reactions. For example, in the synthesis of some new heterocyclic drugs with potential therapeutic effects, 4-methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile may act as a starting material or an important intermediate. By carefully designing the reaction path, adding specific substituents or performing cyclization reactions, complex and biologically active drug molecular structures are gradually constructed.
In the field of materials science, it may also have its uses. During the preparation of some organic optoelectronic materials, due to its unique molecular structure and electronic properties, this compound may participate in the construction of special functional materials, such as used in organic Light Emitting Diode (OLED), organic solar cells and other devices, which affect the photoelectric properties of materials such as luminous efficiency and charge transfer ability, thereby improving the performance of related devices.
Furthermore, in the study of organic synthesis methodology, 4-methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile can be used as a model substrate to explore novel and efficient synthesis reactions. Chemists have developed new reaction conditions, catalysts or reaction strategies around it, aiming to achieve greener, more convenient and more selective organic synthesis, contributing to the development of the field of organic chemistry.

To prepare 4-methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile, there are various methods. One common method is to use nitrogen-containing and oxygen-containing compounds as starting materials and obtain them through multiple delicate reactions.
First take an appropriate pyridine derivative, which needs to have a modifiable group to facilitate subsequent reactions. In a suitable reaction vessel, add an appropriate amount of pyridine derivatives, and then add a specific alkoxylation reagent, which can effectively introduce methoxy groups. During the reaction, control the temperature, pressure and reaction time to ensure a smooth and orderly reaction. After the alkoxylation reaction is completed, a methoxy-containing pyridine intermediate is obtained.
Then, the intermediate is oxidized. Select a strong oxidizing reagent, such as a specific metal oxide or a high-valence oxyacid, etc., to oxidize the specific position of the intermediate to form a 2-oxo structure. In this step, the reaction conditions need to be precisely controlled to avoid excessive oxidation and impurity of the product.
Then the oxidized product is reacted with the cyanide-containing reagent. This cyanide-containing reagent, either potassium cyanide, sodium cyanide, etc., or an organic cyanide reagent, under the action of suitable solvents and catalysts, successfully accesses the cyanyl group to the 3-position of the pyridine ring, and finally obtains 4-methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile.
There are also other methods, or starting from different starting materials, or making the order of the above steps and reagents slightly easier, but they all require exquisite design and rigorous operation to obtain this product. All methods require the experimenter to carefully consider the details of each reaction in order to achieve the best synthetic effect.

4-Methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile is a kind of organic compound. Its physical properties are very important, and it is related to its performance in various chemical processes and practical applications.
The color state of this compound is often white to light yellow crystalline powder. In general, the texture is uniform and fine, and the powder particles are fine and well dispersed. The appearance of this color state, or the interaction between atoms and groups in the molecular structure, causes it to absorb and reflect visible light with a specific pattern.
Its melting point is also a key physical property. It has been experimentally determined that the melting point of 4-methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile is about a certain temperature range. The existence of the melting point is due to the fact that when the temperature rises to a certain level, the forces between molecules, such as van der Waals forces, hydrogen bonds, etc., are overcome by sufficient energy, the lattice structure disintegrates, and the substance changes from solid to liquid. The characteristics of this melting point can be used for the purity identification and separation and purification of the compound.
Furthermore, the solubility cannot be ignored. In common organic solvents, their solubility varies. In polar organic solvents such as methanol and ethanol, or with a certain solubility, there are polar methoxy and cyanyl groups in the molecular structure of the cause, which can form intermolecular forces with polar solvent molecules, such as hydrogen bonds, dipole-dipole interactions, etc., to promote their dissolution. In non-polar solvents such as n-hexane, the solubility is relatively low, because the interaction between the non-polar hydrocarbon skeleton and the non-polar solvent is weak.
In addition, the density of the compound is also one of its physical properties. Although the exact density value needs to be determined by professional instruments, it can be inferred that its density is closely related to the molecular structure. The relative mass of the molecule and the spatial arrangement of the molecule jointly determine its mass in unit volume, that is, density.
In summary, the color state, melting point, solubility and density of 4-methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile are determined by its unique molecular structure, and play an important role in chemical research and practical applications.

4-Methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile is one of the organic compounds. It has many unique chemical properties.
First of all, this substance contains a nitrile group (-CN), and the nitrile group is active and can participate in a variety of reactions. If under appropriate conditions, the nitrile group can be hydrolyzed and converted into a carboxylic group (-COOH), through which the corresponding carboxylic acid derivatives can be prepared, which is of great significance in the field of organic synthesis.
Furthermore, the pyridine ring structure in the molecule endows it with a certain aromaticity. Although it is a dihydropyridine structure, it still retains some of the characteristics of the pyridine ring, which has a great impact on the stability and reactivity of the molecule. Substituents on the pyridine ring, such as methoxy at 4-position (-OCH 🥰) and carbonyl at 2-position (-CO -), also play a significant role in its chemical properties. Methoxy is a power supply group, which can enhance the electron cloud density of the pyridine ring, thereby affecting its electrophilic substitution activity and check point selectivity; 2-position carbonyl can undergo reactions such as nucleophilic addition, and react with reagents containing active hydrogen, such as water, alcohol, and amine, to generate corresponding addition products.
In addition, in the structure of 1,2-dihydropyridine, the dihydrogen part has certain reductivity. Under the action of suitable oxidants, it can be oxidized into pyridine derivatives to realize the transformation between different oxidation states, which is a key reaction step in the design of organic synthesis routes. At the same time, the physical properties of the compound, such as melting point, boiling point, solubility, etc., are affected by the interaction of various groups in the molecular structure, which is also crucial for its separation, purification and practical application. Its solubility depends on the molecular polarity. Nitrile and carbonyl are polar groups, and methoxy also has a certain polarity. The overall polarity affects its dissolution behavior in different solvents, providing a basis for the selection of suitable solvents in practical operation.

4-Methoxy-2-oxo-1,2-dihydropyridine-3-formonitrile is in the market, what is the price? This is a fine chemical product, and its price often changes due to multiple reasons.
First, the amount is the key. If the purchase volume is huge, the merchant may give a discount to promote the sale, and the unit price will be lower; if the purchase quantity is small, the merchant will calculate the cost, and the unit price may be higher.
Second, the quality is also important. High quality, the preparation process or more refined, the raw material or more pure, and its price is higher than that of ordinary quality.
Third, the supply and demand of the market determines the price. If there are many applicants and few suppliers, the price will rise; if the supply exceeds the demand, the price will be depressed.
Fourth, the price varies depending on the source. Those who are known as big factories may have higher prices than small factory products due to brand, quality control and other factors.
Then check the market, the unit price of this product can range from tens of yuan per gram to hundreds of yuan at most. If purchased in batches, it can cost thousands of yuan per kilogram. This is only an approximate number. The actual price must be consulted with the chemical supplier, and the real-time quotation shall prevail.