4 Methoxy 1h Pyrrolo 2 3 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

4-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE

    Specifications

    HS Code

    699624

    Chemical Formula C8H8N2O
    Molar Mass 148.16 g/mol
    Appearance Solid (predicted)
    Solubility In Water Poor (predicted for organic heterocyclic compound)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 4-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4-methoxy-1H-pyrrolido [2,3-b] pyridine?
    4-Methoxy-1H-pyrrolido [2,3-b] pyridine, which is an organic compound. Its chemical structure is quite unique. It is formed by the conjugation of pyridine and pyrrole, and is connected to the pyrrole ring at the 2,3 position of pyridine, and has a methoxy group at the 4 position of pyrrole.
    The pyridine ring is a six-membered nitrogen-containing heterocyclic ring, which is aromatic. The lone pair electron of the nitrogen atom does not participate in the conjugation system, making the pyrrole ring weakly basic. The pyrrole ring is a five-membered nitrogen-containing heterocyclic ring, and the lone pair electron of the nitrogen atom participates in the conjugation, which makes the pyrrole ring After the two are combined, they affect the electron cloud distribution and endow the compound with unique chemical activity. The methoxy group at the position of
    4, the lone pair of electrons of the oxygen atom in -OCH can conjugate with the pyrrole ring, which affects the electron cloud density on the ring. The methyl group is the power supply group, which affects the electron cloud distribution and chemical properties of the whole molecule by inducing the effect to the oxygen atom. This structure makes the compound play an important role in organic synthesis and pharmaceutical chemistry, or can participate in many organic reactions as a key intermediate, or has potential application value in drug development due to its unique structure and activity.
    What are the main uses of 4-methoxy-1H-pyrrolido [2,3-b] pyridine?
    4-Methoxy-1H-pyrrolido [2,3-b] pyridine has a wide range of uses. In the field of medicinal chemistry, it is a key class of organic synthesis intermediates. Due to its unique chemical structure, it can participate in a variety of chemical reactions, and then synthesize compounds with special pharmacological activities. In the process of many drug development, this is used as the starting material or key structural fragment, and ingenious chemical modification and derivatization reactions can create new therapeutic drugs, such as anti-tumor drugs, neurological diseases, etc.
    In the field of materials science, 4-methoxy-1H-pyrrolido [2,3-b] pyridine also shows potential value. It can be used as a basic unit for building functional organic materials, endowing materials with specific electrical and optical properties. For example, in the design and preparation of organic semiconductor materials, the introduction of this structure helps to regulate the charge transport properties and light absorption properties of materials, providing assistance for the development of organic electronic devices, such as organic Light Emitting Diodes (OLEDs) and organic field effect transistors (OFETs).
    Used in the field of fine chemicals, it is often used to synthesize high-end fine chemicals. Due to its unique structure, it can add special properties to products, such as dyes and fragrance additives for special properties, to improve product quality and performance, and meet the specific needs of different industries for fine chemicals. In conclusion, 4-methoxy-1H-pyrrolido [2,3-b] pyridine, with its unique structure, plays an important role in many fields, promoting the development and innovation of related industries.
    What are the physical properties of 4-methoxy-1H-pyrrolido [2,3-b] pyridine?
    4-Methoxy-1H-pyrrolido [2,3-b] pyridine, which is an organic compound with unique physical properties.
    Looking at its properties, it is mostly in a solid state under normal conditions, but the specific physical form may vary depending on the purity and environmental conditions. Its melting point and boiling point are key physical parameters. The melting point can help to determine its purity. The boiling point is related to its phase transition under specific conditions. However, these two values will vary due to surrounding pressure and impurities contained in the compound.
    Solubility is also an important property. In organic solvents, such as common ethanol, dichloromethane, 4-methoxy-1H-pyrrolido [2,3-b] pyridine or exhibit a certain solubility, which is crucial in the extraction, separation and reaction operations of compounds. In water, its solubility is poor, because its molecular structure contains hydrophobic groups, resulting in weak interaction with water molecules.
    In addition, the density and stability of the compound also need to be considered. Density determines its distribution in a specific system, and stability depends on whether it can maintain structural integrity under different environmental conditions. Under normal conditions, if the chemical bond energy in the structure is high and the molecular configuration is stable, its chemical stability may be better; but under extreme conditions such as high temperature, strong acid, and strong base, structural changes and chemical reactions may be triggered.
    Furthermore, the spectral properties of 4-methoxy-1H-pyrrolido [2,3-b] pyridine cannot be ignored. Through infrared spectroscopy, the vibration absorption peak of specific chemical bonds in the molecule can be identified to determine its functional groups; nuclear magnetic resonance spectroscopy can provide information on the chemical environment of hydrogen and carbon atoms in the molecule, which helps to analyze its fine structure. These spectral properties provide powerful means for its identification and structural analysis.
    What are the synthesis methods of 4-methoxy-1H-pyrrolido [2,3-b] pyridine?
    The synthesis of 4-methylamino-1H-pyrrolido [2,3-b] pyridine involves a variety of approaches. One is through the conversion of pyridine derivatives. First, a suitable pyridine starting material is taken, and a specific reagent is used to introduce a methylamino group at a specific position in the pyridine ring through nucleophilic substitution. This step requires fine regulation of the reaction conditions, such as temperature, pH, and the ratio of reactants, to increase the selectivity and yield of the reaction. Then, the dense ring structure of pyrrolido [2,3-b] pyridine is constructed by intramolecular cyclization. This process may require the assistance of a catalyst to promote the smooth progress of the cyclization process.
    Second, pyrrole derivatives can be used as a starting point. First, pyrrole is modified, and suitable substituents are added. Then, it is connected with the pyridine-containing structure fragments through condensation reaction. Then, through a series of steps such as cyclization and modification, the target product is obtained. In this path, the selection and modification of pyrrole derivatives, as well as the optimization of condensation and cyclization reaction conditions, are all key points.
    or synthesized by multi-step tandem reaction. Starting with simple raw materials, with an ingeniously designed reaction process, through several consecutive steps of reaction, the target molecular skeleton is constructed step by step. This strategy requires in-depth understanding of the reaction mechanism of each step and the properties of intermediate products in order to effectively avoid side reactions and improve the synthesis efficiency.
    Synthesis methods have their own advantages and disadvantages. It is necessary to carefully choose the optimal path according to actual needs, such as the availability of raw materials, the difficulty of controlling reaction conditions, and cost considerations, in order to efficiently prepare 4-methylamino-1H-pyrrolido [2,3-b] pyridine.
    What is the market price of 4-methoxy-1H-pyrrolido [2,3-b] pyridine?
    I look at what you said about "4-methoxy-1H-pyrrolido [2,3-b] pyridine", which is an important chemical substance in the field of fine chemicals. Its price in the market is difficult to generalize, because it is affected by many factors.
    The first to bear the brunt is the purity. If the purity of this product is extremely high, it is almost pure, and it must be expensive. Because of its complicated purification process, it requires a lot of manpower, material resources and financial resources to remove impurities and achieve extremely high purity, so its price is high. If the purity is above 99%, the price per gram may reach tens of gold, or even hundreds of gold.
    Furthermore, the market supply and demand is also the key. If there is a sudden increase in demand for it in many industries, such as the field of pharmaceutical research and development, if you want to use it as a raw material to synthesize special drugs, the demand will surge, and the supply will be difficult to cope for a while, and the price will rise. On the contrary, if the supply exceeds the demand, merchants will sell their products or reduce the price in order to sell them.
    The difficulty of the production process also affects the price. If the preparation of this compound requires special reaction conditions, such as high temperature, high pressure, or the use of expensive catalysts, the cost will increase, and the price will also rise.
    In addition, the cost of raw materials should not be underestimated. If the raw materials required for the synthesis of "4-methoxy-1H-pyrrolido [2,3-b] pyridine" are scarce and expensive, the price of the finished product will not be cheap.
    Overall, the market price of "4-methoxy-1H-pyrrolido [2,3-b] pyridine" fluctuates, ranging from a few gold per gram to more than 100 gold per gram, depending on the above factors.