4-iodo-2-(trifluoromethyl)pyridine

4-Iodo-2- (trifluoromethyl) pyridine (4-iodo-2- (trifluoromethyl) pyridine) is also an important intermediate in organic synthesis. It is widely used in the field of medicinal chemistry.
The development process of Guanfu Medicine and the creation of many new drugs often rely on such fluorine-containing and iodine-containing pyridine derivatives. Gein fluorine atoms have unique electronic effects and physiological activities, which can significantly change the lipid solubility and metabolic stability of compounds; while iodine atoms are used in organic synthesis to facilitate the introduction of other functional groups, such as participating in coupling reactions. Taking the research and development of anti-cancer drugs as an example, 4-iodine-2 - (trifluoromethyl) pyridine may be used to construct a molecular skeleton with specific spatial structure and biological activity through a series of reactions to effectively inhibit the proliferation of cancer cells.
In the field of materials science, this compound can also be used. Or it can be used to prepare materials with special photoelectric properties. Due to the introduction of fluorine and iodine atoms, the electron cloud distribution of the material can be adjusted, which in turn affects its optical and electrical properties. For example, in the design of organic Light Emitting Diode (OLED) materials, based on this raw material, through rational molecular design and synthesis, it is expected to obtain new luminescent materials with high luminous efficiency and good stability, which will promote the progress of display technology.
Furthermore, in the field of pesticide chemistry, 4-iodine-2- (trifluoromethyl) pyridine can also play an important role. It can be used as a key intermediate for the synthesis of high-efficiency and low-toxicity pesticides. By ingeniously constructing molecular structures, pesticides are endowed with good biological activity and environmental compatibility to meet the needs of modern agriculture for green and environmentally friendly pesticides.
In summary, 4-iodine-2- (trifluoromethyl) pyridine has important uses in many fields such as medicine, materials, and pesticides due to its unique structure, and has made great contributions to the development of related fields.

4-Iodo-2 - (trifluoromethyl) pyridine is an organic compound, and its physical properties are particularly important, which is related to many properties and uses of this compound.
This compound is usually in a liquid state at room temperature, which is determined by the intermolecular forces. The intermolecular forces are weak, resulting in a flowing state at common ambient temperatures. Its boiling point is about [X] ° C, and the boiling point reflects the difficulty of the molecule leaving the liquid phase and entering the gas phase. The boiling point of the compound is related to the molecular weight and the intermolecular forces. Heavier molecules and stronger forces increase the boiling point.
The melting point is about [X] ° C, and the melting point is the temperature at which the substance changes from solid to liquid. The melting point of this compound varies depending on the crystal structure and the interaction between molecules. The specific crystal arrangement and force stabilize the melting point at this value.
4-iodo-2 - (trifluoromethyl) pyridine has a density of about [X] g/cm ³, and the density is the mass of the substance per unit volume. This value depends on the molecular weight and the degree of molecular packing compactness.
Its solubility is also an important property. It has good solubility in organic solvents such as dichloromethane and chloroform. Due to the principle of "similar miscibility", this compound has a similar structure and polarity to organic solvents, so it can be miscible with each other. However, the solubility in water is not good, because the molecular polarity is quite different from that of water molecules, it is difficult to form effective interactions.
In appearance, this compound is mostly a colorless to light yellow transparent liquid. This color is related to purity, and impurities exist or cause color changes.
In addition, 4-iodo-2 - (trifluoromethyl) pyridine is volatile to a certain extent. Although the volatility is not extremely strong, it will evaporate slowly in the open system. Due to the thermal movement of the molecule, some molecules obtain enough energy to escape the liquid phase.
In summary, the physical properties of 4-iodo-2 - (trifluoromethyl) pyridine, such as liquid state, specific melting boiling point, density, solubility, appearance, and volatility, play an important role in guiding its storage, transportation, use, and chemical reaction applications.

4-Iodine-2- (trifluoromethyl) pyridine is an important intermediate in organic synthesis. The synthesis method has been explored by many scholars in the past, and is briefly described below today.
One method is to use 2- (trifluoromethyl) pyridine as the starting material and obtain it by halogenation reaction. In this reaction, the selection of halogenating reagents is the key. If iodine is used in combination with an appropriate oxidizing agent, under suitable reaction conditions, the 4-position on the pyridine ring can be introduced into the iodine atom. This process requires detailed investigation of the reaction temperature, reaction time and the dosage ratio of reagents in order to achieve the best reaction effect. < Br >
The second method, or can be started from pyridine derivatives containing specific substituents, and the target molecule can be gradually constructed through multi-step reactions. First, a suitable functional group is introduced at a specific position of the pyridine ring, and then through functional group conversion, halogenation and other steps, the final product is 4-iodine-2 - (trifluoromethyl) pyridine. Although this path is more complicated, the reaction steps can be flexibly adjusted according to the availability of raw materials and the selectivity of the reaction to achieve the purpose of synthesis.
This method is also synthesized by a coupling reaction catalyzed by transition metals. Selecting suitable iodine-containing reagents and substrates containing 2- (trifluoromethyl) pyridine structure can achieve the formation of carbon-iodine bonds under the action of transition metal catalysts. Among them, factors such as the type of catalyst, the choice of ligand and the reaction solvent all have a great influence on the activity and selectivity of the reaction.
There are many methods for synthesizing 4-iodine-2- (trifluoromethyl) pyridine, each method has its own advantages and disadvantages, and it is necessary to choose the good one according to the actual situation, such as the cost of raw materials, the difficulty of reaction, the purity of the product, etc., in order to efficiently obtain this important organic intermediate.

4-Iodine-2- (trifluoromethyl) pyridine is a chemical commonly used in organic synthesis. When storing and transporting, there are several ends that need to be paid attention to.
The first word is storage, this substance is quite sensitive to air and moisture. Therefore, when placed in a dry and well-ventilated place, it should be sealed and stored to prevent it from reacting with water vapor and oxygen in the air and causing quality damage. Storage temperature should also be paid attention to, and it should be controlled at room temperature, but it should not be exposed to high temperature or direct sunlight to avoid decomposition or other adverse chemical changes.
As for transportation, because it may be dangerous, it is necessary to follow relevant regulations and standards. Before transportation, it is necessary to ensure that the packaging is solid and reliable to prevent leakage. The packaging materials used should be able to resist vibration, collision and friction, and have good sealing properties. During transportation, sudden changes in temperature and violent vibration should also be avoided to prevent package damage or unstable reactions of substances.
In addition, whether it is storage or transportation, it should be kept away from fire sources, heat sources and strong oxidants. Due to its active chemical nature, there may be a risk of fire or explosion in case of such substances. At the same time, the storage and transportation places should be equipped with appropriate fire and leakage emergency treatment equipment for emergencies. Those who operate this chemical must also be professionally trained to know its characteristics and safety precautions, so as to ensure the safety of storage and transportation.

4-Iodo-2 - (trifluoromethyl) pyridine is an organic compound, and the market price often varies greatly due to purity, purchase quantity and suppliers.
In the context of ancient books such as "Tiangong Kaiwu", although there was no transaction price of this fine chemical at that time, there may be something to refer to in today's analogous business logic. In the current chemical raw material market, if the purity of this compound is average, buy it in small quantities (such as a few grams), and the price per gram may range from tens of yuan to hundreds of yuan. Because the preparation of this compound requires specific organic synthesis steps, the cost of raw materials, the control of reaction conditions and the purification process all affect the price.
If the purchase volume increases, such as reaching the order of hundreds of grams or even kilograms, the unit price may be significantly reduced due to the scale effect, falling to a few yuan to tens of yuan per gram. And high-purity products, due to the difficulty of purification, the price is much higher than that of ordinary purity, or more than 100 yuan per gram.
In short, its market price is affected by many factors. To obtain the exact price, you need to consult the chemical raw material supplier in detail and negotiate according to specific needs.