4-Iodo-1H-pyrazolo[3,4-b]pyridine

4-Iodine-1H-pyrazolo [3,4-b] pyridine is one of the organic compounds. Its physical properties are particularly important and are related to many applications of this compound.
The first word about its appearance is usually in the form of a solid powder similar to white to light yellow. This color state is easy to observe and identify, and is significant in laboratory operations and at the beginning of industrial production. Its solid form also makes it easy to store and transport, and it has better stability than liquid or gaseous states.
The melting point of 4-iodine-1H-pyrazolo [3,4-b] pyridine is within a specific range, but the exact value varies depending on the purity and test conditions. The determination of the melting point is crucial for the identification of its purity and the confirmation of its material characteristics. The melting point of this compound with high purity is relatively stable and close to the theoretical value; if it contains impurities, the melting point may be offset.
The other is solubility. This compound has different solubility in common organic solvents. In organic solvents such as dichloromethane, N, N-dimethylformamide, it exhibits a certain solubility. This property allows it to be used as a reactant or intermediate in organic synthesis reactions, and to achieve homogeneous reactions with the help of suitable solvents to improve reaction efficiency and selectivity. In water, its solubility is low, and this property also affects its behavior in biological systems or aqueous environments.
Its density is also one of the important physical properties. Although the specific density value also needs to be accurately measured, this parameter is of great significance in operations involving mass and volume conversion, such as solution preparation, reaction material measurement, etc. Proper control of density can ensure that the amount of material used in the experiment or production process is accurate.
In addition, the stability of 4-iodine-1H-pyrazolo [3,4-b] pyridine is also a physical property consideration. Under normal temperature and pressure, it has a certain stability, but when exposed to high temperature, strong oxidants or specific chemical environments, or chemical reactions occur, resulting in changes in structure and properties. Knowing this stability is crucial in setting storage conditions and selecting usage scenarios.

4-Iodo-1H-pyrazolo [3,4-b] pyridine is an organic compound with unique chemical properties. Its appearance is often solid, which is caused by intermolecular forces. In terms of solubility, the compound exhibits some solubility in organic solvents, such as common ethanol and dichloromethane. This property is due to the specific interactions between its molecular structure and organic solvent molecules, such as van der Waals forces, hydrogen bonds, etc.
In terms of stability, 4-Iodo-1H-pyrazolo [3,4-b] pyridine is relatively stable under conventional environmental conditions. However, under extreme conditions such as high temperature, strong oxidants or strong bases, its structure is easily damaged. Due to high temperature, the thermal motion of the molecule will be intensified, resulting in the weakening of chemical bonds; strong oxidants and strong bases can chemically react with specific functional groups in the molecule, thereby changing its structure.
The reactivity of this compound is quite interesting. The iodine atom in the molecule is an activity check point and is easy to participate in nucleophilic substitution reactions. Because of its high electron cloud density, iodine atoms are vulnerable to attack by nucleophilic reagents and form new chemical bonds after leaving. In addition, the pyrazole-pyridine skeleton also gives it unique reactivity, which can participate in various cyclization reactions, metal catalytic reactions, etc. This kind of reactivity makes it highly valuable in the field of organic synthesis, and is often used as a key intermediate to prepare more complex organic compounds. It has potential applications in many fields such as medicinal chemistry and materials science.

4-Iodo-1H-pyrazolo [3,4-b] pyridine is an organic compound that has important uses in many fields such as medicinal chemistry and materials science.
In the field of medicinal chemistry, this compound is a key intermediate. Due to its unique chemical structure, it can be modified by various chemical reactions to synthesize biologically active molecules. In the process of many drug development, scientists hope to introduce specific functional groups into this compound to create new drugs with high affinity and selectivity for specific disease targets. For example, for certain cancers, researchers can modify the structure of 4-Iodo-1H-pyrazolo [3,4-b] pyridine to synthesize drug molecules that can precisely inhibit the proliferation of cancer cells or induce their apoptosis. Studies have also tried to use this compound to develop therapeutic drugs for neurological diseases, such as Alzheimer's disease and Parkinson's disease, and to regulate neurotransmitter metabolism or inhibit neuroinflammatory responses through its structural properties.
In the field of materials science, 4-Iodo-1H-pyrazolo [3,4-b] pyridine also has good performance. It can participate in the construction of materials with special photoelectric properties. For example, in the development of organic Light Emitting Diode (OLED) materials, the compound is introduced into polymer materials as a structural unit to adjust the luminous properties of the materials, improve luminous efficiency and color purity. Due to the synergistic effect of iodine atoms and pyrazolopyridine structures, it can affect the electron transport and energy level distribution in the material, thereby optimizing the performance of OLED devices. In the research of organic solar cell materials, this compound may also be able to improve the absorption of light and charge separation efficiency of the material by combining with other conjugated systems, and promote the improvement of the energy conversion efficiency of solar cells.
In summary, 4-Iodo-1H-pyrazolo [3,4-b] pyridine has shown broad application prospects in the fields of medicine and materials due to its unique structure, providing an important material basis for the innovation and development of related fields.

The synthesis methods of 4-iodine-1H-pyrazolo [3,4-b] pyridine have been investigated throughout the ages. In the past, although the methods of organic synthesis were not as rich as they are today, scholars have also made great efforts to find a way to synthesize this compound.
Early synthesis pathways often use pyridine derivatives as starting materials. A specific substituent is introduced into the pyridine ring first, and the pyrazole ring structure is constructed through multi-step reactions. During this process, iodine atoms need to be introduced precisely through halogenation reactions. In this process, the choice of halogenation reagents is crucial, such as the combination of iodine elements with suitable catalysts, or the use of specific organic iodine reagents, which can affect the location and efficiency of iodine atom introduction.
Furthermore, the synthesis strategy using pyrazole derivatives as initiators has also attracted much attention. Through ingenious reaction design, the pyridine fragment is connected to the pyrazole ring to build the skeleton of the target compound. In this path, the reaction step connecting the pyridine and the pyrazole ring requires fine regulation of the reaction conditions, such as temperature, solvent, and type of base, to ensure that the reaction proceeds in the desired direction.
In recent times, with the rapid development of organic synthesis technology, new synthesis methods have emerged one after another. Transition metal-catalyzed reactions, such as palladium-catalyzed cross-coupling reactions, open up new avenues for the synthesis of 4-iodine-1H-pyrazolo [3,4-b] pyridine. With the help of such reactions, iodine atoms can be introduced at specific locations more efficiently and precisely, and the reaction steps can be optimized to improve the overall synthesis efficiency. In addition, new technologies such as microwave radiation and photocatalysis are gradually applied to the synthesis of this compound, showing unique advantages such as short reaction time and high yield.

I look at your question, but I am inquiring about the market price of 4 - Iodo - 1H - pyrazolo [3,4 - b] pyridine. However, the price of this product is difficult to determine. The price is affected by many factors and cannot be generalized.
First, it is about purity. If the purity is very high, it is almost perfect, and the price is high; if the purity is slightly inferior and contains some impurities, the price is slightly cheaper. This reason is easy to understand. Those with high purity are more difficult to prepare, and the required process and cost are increased, so the price is high.
Second, the amount is also the main reason. The purchase volume is vast, and the merchant may offer a preferential price in order to promote the sale; if only a small amount is required for testing and the like, the price will be high. Cover a small amount of transactions, the profit of the merchant is thin, so the price cannot be low.
Third, the supply and demand of the city have a deep impact. If there are many people in demand for this product, but the supply is limited, the so-called supply outstrips the demand, and the price will rise; on the contrary, if the supply exceeds the demand, the merchant will clear the inventory, and the price may drop.
Fourth, the difficulty of making it also affects the price. If the preparation requires complicated and difficult processes, and rare raw materials are used, the cost will increase greatly and the price will also be high; if the preparation is easier, the cost will decrease and the price will also decrease
The price is not known in the market today. To get an accurate price, you can consult the chemical raw material supplier, or check it on the relevant chemical product trading platform. However, the price obtained is only the price at that time, and the price may vary from time to time due to changes in the above reasons.