4 Hydroxy 6 Methyl 2 Oxo 1 2 Dihydropyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid

    Specifications

    HS Code

    780751

    Chemical Formula C7H7NO4
    Molecular Weight 169.14 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point Decomposes rather than having a distinct melting point (approx. above 250°C)
    Solubility Slightly soluble in water, more soluble in polar organic solvents like DMSO
    Pka pKa1 ≈ 2.6 (carboxylic acid group), pKa2 ≈ 10.3 (enol - keto equilibrium related)
    Functional Groups Carboxylic acid, carbonyl, enolizable ketone, pyridine - like ring
    Uv Absorption Absorbs in the ultraviolet region, typically around 260 - 280 nm
    Ir Absorption Carbonyl stretch around 1700 - 1750 cm⁻¹ (C=O of ketone and carboxylic acid), O - H stretch around 2500 - 3500 cm⁻¹ (carboxylic acid OH), C - H stretches in the range 2800 - 3000 cm⁻¹
    Stability Stable under normal conditions, but sensitive to strong acids, bases and high temperatures

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    Frequently Asked Questions

    As a leading 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    4-hydroxy-6-methyl-2-oxo-1, what is the chemistry of 2-dihydropyridine-3-carboxylic acid?
    4-Hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid, this is an organic compound. Looking at its structure, it contains a pyridine ring and is connected with functional groups such as hydroxyl, methyl, carbonyl and carboxyl at specific positions.
    This compound is acidic because it contains carboxyl groups and can neutralize with bases to form corresponding carboxylic salts. Its hydroxyl groups also have certain reactivity and can participate in reactions such as esterification. Under suitable conditions, it can be esterified with alcohols to form ester compounds.
    Furthermore, the conjugate system of the pyridine ring gives it a certain stability, but the functional groups attached to the ring affect the distribution of its electron cloud, so that the specific positions on the ring show different reactivity, or electrophilic substitution reactions can be carried out.
    Its carbonyl group is also an important reaction check point, which can participate in reactions such as nucleophilic addition, such as reacting with nucleophilic reagents containing active hydrogen.
    In addition, the physical properties of the compound, in view of containing polar functional groups, or showing certain solubility in polar solvents. Its melting point, boiling point and other physical parameters are determined by intermolecular forces, such as hydrogen bonds, van der Waals forces, etc. Because carboxyl and hydroxyl groups can form hydrogen bonds, or the melting point and boiling point are higher than those of compounds with similar structures but no such strong hydrogen bonds.
    4-hydroxy-6-methyl-2-oxo-1, what are the common uses of 2-dihydropyridine-3-carboxylic acid
    4-Hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid, this is an organic compound. Its common uses are of great research value.
    First, in the field of medicine, it can be used as a key intermediate for the synthesis of drugs. Due to the unique chemical structure of this compound, it can interact with specific targets in organisms. For example, in the synthesis process of some cardiovascular drugs, this is used as the starting material, and through a series of delicate chemical reactions, drug molecules with functions such as regulating blood pressure and improving heart function can be constructed. By modifying and modifying its structure, the activity and selectivity of drugs can be precisely regulated, thereby improving the therapeutic effect of drugs and reducing adverse reactions.
    Second, it can also be seen in the field of materials science. Because of its certain stability and special chemical properties, it can be used to prepare functional materials. Such as participating in the preparation of some polymer materials with specific optical or electrical properties. In the polymerization process, 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid, as a functional monomer, can endow the material with unique properties, such as fluorescence properties or electrical conductivity, and then expand the application of the material in optical devices, electronic components, etc.
    Third, in organic synthesis chemistry, this compound is often used as a basic module for building complex organic molecules. Due to the fact that its structure contains multiple reactive functional groups, such as hydroxyl groups, carboxyl groups, and pyridine rings, chemists can skillfully utilize the reactivity of these functional groups to combine them with other organic fragments through classical organic reactions such as esterification, amidation, and nucleophilic substitution reactions to construct organic compounds with diverse structures and functions, providing rich raw materials and pathways for the development of organic synthetic chemistry.
    4-hydroxy-6-methyl-2-oxo-1, what is the synthesis method of 2-dihydropyridine-3-carboxylic acid
    To prepare 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid, there are several common methods as follows.
    First, it can be converted from a suitable nitrogen-containing heterocyclic precursor through a specific reaction. For example, select a pyridine derivative with appropriate substituents, and achieve the construction of the target product through precise oxidation and hydroxylation reactions. In this process, careful selection of oxidizing agents and hydroxylating reagents is required to ensure that the reaction can be carried out efficiently and selectively.
    Second, it can also be prepared by multi-step condensation reaction. First, a simple organic compound containing carboxyl, hydroxyl and methyl groups is used as the starting material, and the basic structure of the pyridine ring is formed by condensation. In this step, the reaction conditions, such as temperature, pH and reaction time, must be strictly controlled, so that the condensation reaction of each step proceeds according to the expected direction. For example, the esterification reaction of carboxylic acid and alcohol can be used, and then cyclization and condensation with nitrogen-containing compounds can occur, followed by hydrolysis and other reactions to introduce the required hydroxyl and carbonyl groups.
    Third, the reaction path catalyzed by transition metals can also be considered. Transition metal complexes are used as catalysts to catalyze the coupling and cyclization reactions between specific organic substrates, thereby obtaining the target product. In this method, the selection of catalysts, the design of ligands, and the selection of reaction solvents all have a significant impact on the success or failure of the reaction and the yield.
    To synthesize 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid, it is necessary to weigh the advantages and disadvantages of each method according to the actual situation, carefully design the synthesis route, and strictly control the reaction conditions, in order to achieve efficient and high-quality synthesis.
    4-hydroxy-6-methyl-2-oxo-1, what is the market price of 2-dihydropyridine-3-carboxylic acid?
    I don't know what the market price of "4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid" is. This compound is not a common and well-known product, and its price may vary greatly due to many factors.
    First, the purity has a great impact. If the purity is extremely high, it is almost flawless, and it is suitable for extremely harsh scenarios such as high-end scientific research experiments, its price will be high. If the purity is slightly lower, it can only be used for general industrial use, and the price should be low.
    Second, the yield is also the key. If the output of this product is rare, such as rare treasures, the price will be high. On the contrary, if the production technology is mature, the output is considerable, and the price may be close to the people.
    Third, market demand determines the price. If a certain field is hungry for its demand at a certain time, and the demand exceeds the supply, the price will also rise. If there is little demand and no one cares, the price may tend to be low.
    Fourth, the difficulty of preparation is also related. If the preparation process is cumbersome and complicated, requires many difficult processes, and consumes a lot of manpower, material and financial resources, the price will not be low.
    However, if you want to know the exact market price, you must check the chemical product trading platform, consult professional chemical raw material suppliers or explore at relevant industry exhibitions. This way, more accurate price information can be obtained.
    4-hydroxy-6-methyl-2-oxo-1, how safe is 2-dihydropyridine-3-carboxylic acid?
    4-Hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid, the safety of this substance is related to many aspects.
    In terms of chemical properties, its structure contains functional groups such as hydroxyl groups, carboxyl groups and pyridine rings. Hydroxy groups have certain hydrophilicity, but they can also participate in a variety of chemical reactions, such as esterification. Carboxyl groups are acidic and can be neutralized with bases. These reaction characteristics may cause them to be unstable under specific conditions, and if the reaction is out of control, it may be potentially dangerous.
    From the perspective of toxicity, it is difficult to accurately determine its toxicity without detailed toxicological research data. However, analogous to similar compounds containing pyridine structures, some may have certain toxicity, or can irritate the skin, eyes and respiratory tract. After human contact, it may cause local redness, swelling, pain, or even damage internal organs after percutaneous absorption, inhalation or ingestion.
    When it comes to environmental effects, its degradability in the environment is quite critical. If it is difficult to degrade, or accumulates in the environment, it endangers the ecosystem. Its decomposition products also need to be carefully investigated. If it contains harmful ingredients, it will have adverse effects on soil, water sources and organisms.
    When storing and transporting, due to its chemical properties, it is necessary to avoid high temperature, open flame and strong oxidants. Improper storage, or chemical reactions cause the container to break or leak, increasing the risk. During transportation, it is also necessary to follow specific procedures according to its dangerous characteristics to prevent accidental leakage.
    In summary, although the exact safety of the substance has not been determined, it needs to be treated with caution based on the chemical structure and the characteristics of similar substances. In all aspects of production, use, storage and transportation, safety regulations should be strictly followed to prevent potential hazards.