4-hydroxy-3-pyridinesulphonic acid

4-Hydroxy-3-pyridine sulfonic acid is an organic compound. It has a wide range of uses and plays an important role in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate. In the process of many drug development, 4-hydroxy-3-pyridine sulfonic acid can be converted into compounds with specific pharmacological activities through a series of chemical reactions. For example, the synthesis path of some drugs used to treat cardiovascular diseases and nervous system diseases involves using it as a starting material to give the drug precise therapeutic effect through ingenious construction of molecular structures.
In the field of materials science, it also shows unique value. Can participate in the preparation of high-performance polymer materials. With its own special chemical structure, when polymerized with other monomers, it can optimize the properties of materials, such as improving the stability and mechanical strength of materials. For example, when preparing special engineering plastics, appropriate addition of this compound can significantly improve the heat resistance and corrosion resistance of plastics, expanding its application range in extreme environments.
Furthermore, in the fine chemical industry, 4-hydroxy-3-pyridine sulfonic acid can be used as an important raw material for the synthesis of dyes and pigments. By modifying and reacting with functional groups, bright-colored dyes and pigments with excellent properties can be prepared, which are widely used in textile printing and dyeing, ink manufacturing and other fields to add rich colors to products.
In addition, in some special chemical reactions, it can also act as a catalyst or auxiliary agent to accelerate the reaction process, improve the yield and selectivity of the reaction, and help the chemical production to be more efficient. In short, although 4-hydroxy-3-pyridine sulfonic acid is an organic compound, it plays a key role in promoting the development of many industries with its diverse uses.

4-Hydroxy-3-pyridine sulfonic acid is a special organic compound. Its physical properties are unique. This substance is usually in solid form and is relatively stable under normal temperature and pressure.
Looking at its appearance, it is mostly white or almost white crystalline powder with pure color and fine texture. Its melting point is quite high, and it needs a specific temperature to convert it from solid to liquid. This melting point characteristic is helpful for its separation and purification under specific conditions.
In terms of solubility, 4-hydroxy-3-pyridine sulfonic acid exhibits a certain solubility in water, and can be partially ionized to form corresponding ions under the action of water molecules, which can then be dissolved in the aqueous phase. However, its solubility in organic solvents varies depending on the type of organic solvent. For example, in polar organic solvents such as ethanol, the solubility is relatively good; in non-polar organic solvents such as benzene, the solubility is poor.
Furthermore, 4-hydroxy-3-pyridine sulfonic acid has a certain degree of hygroscopicity. In a humid environment, it is easy to absorb moisture in the air, causing its own state to change, or from a dry powder to a slightly humid mass. Therefore, during storage and use, proper attention should be paid to moisture resistance to maintain its original properties and quality.
In addition, the density of this compound is also one of its important physical properties. Its density determines the mass under a specific volume, which is of great significance for metering and proportioning operations in practical applications. Under different temperature and pressure conditions, its density varies little, but it also needs to be considered in high-precision experiments and industrial production.

The chemical stability of 4-hydroxy-3-pyridine sulfonic acid is related to many aspects. In terms of structure, the hydroxyl group and the sulfonic acid group are combined on the pyridine ring. The hydroxyl group has certain activity and can participate in the formation of hydrogen bonds. Under specific conditions, it may be able to undergo reactions such as substitution and oxidation. The sulfonic acid group, which is highly acidic, is easy to ionize in water, giving the substance good water solubility.
Under normal conditions, without special reagents or external stimuli, the structure of the pyridine ring is relatively stable, but it may be difficult to maintain stability under extreme conditions such as strong oxidizing agents, strong acids and bases. For example, strong oxidizing agents may oxidize hydroxyl groups and cause structural changes; strong acids and bases may affect the ionization balance of sulfonic acid groups, which in turn affects the overall properties.
If it is at room temperature and pressure, and there are no substances with high chemical reactivity, 4-hydroxy-3-pyridine sulfonic acid is relatively stable. However, in the complex environment of chemical production and experimental operations, its stability must be considered in detail according to specific conditions and cannot be generalized.

The synthesis method of 4-hydroxy-3-pyridine sulfonic acid has existed in ancient times, and with the changes of time, the technology has become more and more exquisite. There are many methods, and they are described in detail today.
First, pyridine is used as the starting material, and it is obtained by sulfonation and oxidation in several steps. First, put pyridine in a suitable reactor, add an appropriate amount of sulfonating reagent, such as concentrated sulfuric acid or fuming sulfuric acid, and control its temperature and reaction time. This step requires careful observation of the reaction process. The check point and degree of sulfonation depend on the purity of the product. After the sulfonation is completed, the oxidation step is continued, and a suitable oxidizing agent, such as hydrogen peroxide or potassium permanganate, is selected to oxidize the pyridine ring to a hydroxyl group at a specific position, and the final 4-hydroxy-3-pyridine sulfonic acid is obtained. However, the reaction conditions need to be strictly controlled in this way to prevent the product from being impure or the yield is low due to excessive oxidation.
Second, there are also pyridine derivatives containing specific substituents as starting materials. The carefully designed reaction route, through many reactions such as substitution, elimination, and addition, gradually builds the structure of the target molecule. This approach can precisely regulate the reaction check point according to the characteristics of the raw material and the reaction mechanism, and improve the selectivity and yield of the product. However, it requires high precision control of the purity of the raw material and the reaction.
Third, there is a method based on catalytic synthesis. Select an efficient catalyst to catalyze the conversion of related reactants to 4-hydroxy-3-pyridine sulfonic acid under mild reaction conditions. The advantage of this method is energy saving and consumption reduction, and the selectivity of the catalyst can improve the purity of the product. However, finding a suitable catalyst and optimizing the catalytic reaction conditions are the key points, which require repeated experiments and research by researchers.
The synthesis of 4-hydroxy-3-pyridine sulfonic acid has its own advantages and disadvantages. When choosing the method, the best synthetic effect can be achieved by carefully weighing various factors such as raw material availability, cost considerations, product purity and yield requirements.

The price of 4-hydroxy-3-pyridine sulfonic acid in the market is difficult to determine. There are many reasons to cover its price.
First, the price of raw materials is also. If the price of raw materials required for its preparation changes constantly, the price of 4-hydroxy-3-pyridine sulfonic acid will also change accordingly. If the production of raw materials encounters natural or man-made disasters, resulting in a decrease in their quantity, the price will rise, and the price of this sulfonic acid will also be high.
Second, the market's demand is also high. If at some time, many industries need this sulfonic acid for use in medicine, chemical industry and other fields, the demand is abundant but the supply is not sufficient, and the price will increase. On the contrary, if there is no big demand, the supply is more than the demand, and the price may drop.
Third, the progress of the craft. If the new craft is produced, the production efficiency increases and the cost decreases, the price may drop. However, at the beginning of the new craft, it may encounter setbacks, or it may cause production to be hindered, and the price may be unstable.
Fourth, political regulations. Changes in taxes and environmental protection regulations can affect the cost of its products, and then the price. If taxes increase and environmental protection costs are high, the cost will rise, and the price will also rise.
According to past market conditions, the price of 4-hydroxy-3-pyridine sulfonic acid is between hundreds and thousands of yuan per kilogram. However, this is only a rough estimate, and the actual price should vary depending on the current market conditions, purchase quantity, quality, etc. To know the exact price, it is advisable to consult the merchant of chemical raw materials, the market intermediary, or the real-time market newspaper to get a near-real price.