4 Hydroxy 3 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

4-hydroxy-3-methylpyridine

    Specifications

    HS Code

    407190

    Name 4-hydroxy-3-methylpyridine
    Molecular Formula C6H7NO
    Molar Mass 109.126 g/mol
    Appearance Solid
    Cas Number 1003-67-4
    Boiling Point 266 - 267 °C
    Melting Point 84 - 86 °C
    Solubility In Water Soluble
    Pka 9.67
    Density 1.126 g/cm³ (calculated)
    Odor Odorless (estimated)

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    General Information
    Where to Buy 4-hydroxy-3-methylpyridine in China?
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    Frequently Asked Questions

    As a leading 4-hydroxy-3-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-hydroxy-3-methylpyridine?
    4-Hydroxy-3-methylpyridine is one of the organic compounds. It is weakly basic, and can accept protons because the nitrogen atom of the pyridine ring contains lone pairs of electrons. This property allows it to react with acids to form salts, which can be used as base catalysts in specific chemical reactions.
    is also nucleophilic, and the electron cloud distribution of the pyridine ring makes it nucleophilic in some positions. For example, under suitable conditions, it can be substituted with electrophilic reagents and used in organic synthesis to construct complex molecular structures.
    Because it contains hydroxyl groups, it has a certain acidity. Hydroxyhydrogen can leave under the action of appropriate bases to exhibit acidic properties. At the same time, the hydroxyl group can participate in many reactions, such as esterification reaction, reaction with carboxylic acid or acyl chloride to form corresponding ester compounds, which is very important in the field of organic synthesis and medicinal chemistry.
    In addition, its physical properties are mostly solid at room temperature, and the melting point and boiling point are affected due to the interaction of hydrogen bonds between molecules. And its solubility is related to molecular polarity. It has a certain solubility in some polar solvents such as alcohol and water (due to the formation of hydrogen bonds), but poor solubility in non-polar solvents. In chemical reactions, the chemical properties of 4-hydroxy-3-methylpyridine make it widely used as a key intermediate in many fields such as organic synthesis and drug development.
    What are the main applications of 4-hydroxy-3-methylpyridine?
    4-Hydroxy-3-methylpyridine, which has important applications in many fields. In the field of pharmaceutical chemistry, it is often a key intermediate. The unique structure of the gainpyridine ring with hydroxyl and methyl groups gives it specific chemical activity, which can be converted into various bioactive compounds by chemical reaction. For example, in the synthesis of drugs for the treatment of cardiovascular diseases and nervous system diseases, 4-hydroxy-3-methylpyridine may be used as a starting material to construct complex drug molecular structures through multi-step reactions, which is of great significance for drug development.
    In the field of pesticides, it also has significant uses. It can be used to create new pesticides, because of its structural characteristics, or it can show high activity against specific pests and pathogens, which can help to synthesize high-efficiency, low-toxicity, and environmentally friendly pesticide products, improve crop yield and quality, and reduce adverse effects on the environment.
    Furthermore, in the field of materials science, 4-hydroxy-3-methylpyridine is also involved. Because it has certain reactivity and coordination ability, it can participate in the synthesis of polymer materials, change the properties of materials, such as improving the stability and conductivity of materials, and provide the possibility for the development of new functional materials. In the field of organic synthetic chemistry, as an important building block of organic synthesis, it can participate in many organic reactions, such as nucleophilic substitution, oxidation and reduction, providing a foundation for the construction of diverse organic compound structures, promoting the development of organic synthetic chemistry, helping chemists create more new organic compounds, and expanding the research boundaries of organic chemistry.
    What are 4-hydroxy-3-methylpyridine synthesis methods?
    There are many methods for the synthesis of 4-hydroxy-3-methylpyridine. One is to use 3-methylpyridine as the starting material and obtain it by oxidation. This oxidation method usually uses an appropriate oxidizing agent, such as peroxide, under suitable reaction conditions, to oxidize a specific position on the pyridine ring of 3-methylpyridine, introduce hydroxyl groups, and then obtain 4-hydroxy-3-methylpyridine.
    Furthermore, or it can be synthesized by the technique of functional group transformation starting from the corresponding pyridine derivatives. For example, pyridine derivatives containing suitable substituents are first prepared, and then through specific reactions, such as nucleophilic substitution, reduction and other reaction steps, functional groups are ingeniously converted to gradually build the structure of the target molecule, and finally 4-hydroxy-3-methyl pyridine.
    There are also heterocyclic synthesis strategies. Select appropriate small molecule compounds containing nitrogen and oxygen heteroatoms, and use organic synthesis techniques, such as cyclization reactions, to construct pyridine rings, and precisely introduce 4-hydroxy and 3-methyl substituents into the rings. This process requires fine regulation of reaction conditions, such as temperature, pH, catalyst, etc., to ensure that the reaction proceeds in the expected direction, resulting in a higher yield and purity of 4-hydroxy-3-methylpyridine.
    All these synthesis methods have their own advantages and disadvantages. In practical application, when the availability of raw materials, the difficulty of reaction, the purity requirements of the product and many other factors, the best synthesis effect can be achieved.
    What is the market outlook for 4-hydroxy-3-methylpyridine?
    4-Hydroxy-3-methylpyridine is one of the organic compounds. At present, its market prospect is quite promising and has great potential for development.
    In the field of Guanfu Chemical, this compound has a wide range of uses. It can be a key intermediate in the synthesis of medicine. To cover the development of medicine, the precision of heavy components and the exquisite structure. 4-Hydroxy-3-methylpyridine, with its unique molecular structure, can provide a solid foundation for the construction of drug molecules. In the development process of many new drugs, it is often relied on to help achieve the expected efficacy.
    Furthermore, it is also indispensable in the process of pesticide creation. Today's agriculture strives for efficient and environmentally friendly pesticides. 4-Hydroxy-3-methylpyridine can participate in the synthesis of pesticide ingredients with special activities, which is beneficial to the control of pests and diseases, and has little impact on the environment.
    From the perspective of market demand, with the vigorous rise of the pharmaceutical and pesticide industries, the demand for 4-hydroxy-3-methylpyridine is also on the rise. Pharmaceutical companies continue to expand the territory of new drugs, and pesticide manufacturers strive to improve the efficiency of their products, all of which have contributed to the increasing demand for this substance year after year.
    However, in the market, competition is also quite fierce. Many chemical companies have seen the business opportunities and have thrown themselves into the production of 4-hydroxy-3-methylpyridine. Therefore, in order to take the lead in the market, companies need to improve their production processes and strive for excellence. Optimize the synthesis process and improve the purity and yield of products in order to stand firm in this fierce wave of competition.
    In addition, the power of scientific research cannot be underestimated. Continued in-depth research may open up the use of 4-hydroxy-3-methylpyridine renewal and expand its market boundaries. In this way, its market prospect will be broader and it is expected to usher in a more brilliant development situation.
    4-hydroxy-3-methylpyridine what are the precautions during storage and transportation?
    4-Hydroxy-3-methylpyridine is an organic compound. During storage and transportation, many key matters need to be paid attention to to to ensure its quality and safety.
    When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, because the substance is prone to decomposition or other adverse reactions when heated. The temperature of the warehouse must be strictly controlled, generally not exceeding 30 ° C, and the humidity should be maintained in an appropriate range to prevent moisture decomposition. If the ambient humidity is too high, water vapor may interact with 4-hydroxy-3-methylpyridine, affecting its chemical properties.
    Furthermore, keep away from fire and heat sources. Because of its flammability, in case of open flame, hot topic or cause the risk of combustion. At the same time, it should be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed. 4-Hydroxy-3-methylpyridine is chemically active, and contact with these substances or violent chemical reactions can lead to serious consequences such as explosion.
    Storage containers are also very critical. It is necessary to choose well-sealed containers to prevent them from evaporating or reacting with air components. Commonly used glass bottles or plastic drums are stored, but it is necessary to ensure that the material does not chemically react with 4-hydroxy-3-methylpyridine. The storage area should also be equipped with suitable materials to contain leaks, just in case of leaks and can be dealt with in time.
    During transportation, it is necessary to ensure that the packaging is complete and safely loaded. Packaging materials need to have good protective properties to avoid package damage and leakage due to vibration and collision during transportation. The transportation process should be kept away from high temperature areas and densely populated areas to prevent accidents from causing harm to the public.
    Transportation vehicles must also meet relevant safety standards and be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. Drivers and escorts must be professionally trained and familiar with the dangerous characteristics of 4-hydroxy-3-methylpyridine and emergency treatment methods. Check the status of the goods regularly during transportation. If any signs of package damage or leakage are detected, immediate measures will be taken to prevent the situation from worsening.