4 Hydrazinylpyridinehydrochloride
pyridine pyrrole pyrazine piperidine piperazine

4-Hydrazinylpyridinehydrochloride

    Specifications

    HS Code

    441505

    Name 4 - Hydrazinylpyridinehydrochloride
    Chemical Formula C5H8ClN3
    Molecular Weight 145.59 g/mol
    Appearance Solid (usually white or off - white powder)
    Solubility In Water Soluble in water
    Melting Point Around 200 - 210 °C (approximate, may vary depending on purity)
    Purity Typically available in high - purity grades (e.g., 95%+)
    Odor May have a faint, characteristic odor
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Hazard Class May cause skin, eye, and respiratory irritation (classified as an irritant)

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    General Information
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    Frequently Asked Questions

    As a leading 4-Hydrazinylpyridinehydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Hydrazinylpyridine hydrochloride?
    4-Hydrazinopyridine hydrochloride is an organic compound. It has a wide range of uses and can play important roles in many fields.
    In the field of medicinal chemistry, it is often regarded as a key intermediate. It can be transformed and modified through a series of chemical reactions to synthesize drug molecules with specific biological activities. In many drug development processes, the chemical structure of 4-hydrazinopyridine hydrochloride allows it to participate in the process of building a drug activity skeleton, thus endowing the drug with unique pharmacological properties, such as antibacterial, anti-inflammatory, and anti-tumor effects.
    In the field of materials science, it also shows unique value. For example, it can be used as a functional monomer to participate in the synthesis of polymer materials. With its reactivity of hydrazine and pyridine structures, the synthesized polymer materials can have specific physical and chemical properties, such as selective coordination ability for certain metal ions, and then used to prepare materials with special adsorption properties, or functional materials with fluorescent properties, which have potential applications in sensors, adsorbents, etc.
    In addition, in the field of organic synthetic chemistry, 4-hydrazine pyridine hydrochloride is often used to construct more complex organic molecular structures. Its hydrazine and pyridine rings can be used as reaction check points to react with various electrophilic reagents and nucleophiles, so as to realize the construction of various chemical bonds such as carbon-nitrogen bonds and carbon-carbon bonds, and help synthesize a series of organic compounds with novel structures. It provides an important material basis and synthesis strategy for the development of organic synthetic chemistry.
    What are the physical properties of 4-Hydrazinylpyridine hydrochloride?
    4-Hydrazinopyridine hydrochloride is an organic compound. Its physical properties are very important and are of key significance in chemical research and related applications.
    This substance is mostly in solid form at room temperature, and its appearance is usually white or off-white crystalline powder. Because its molecular structure contains special functional groups, it has a certain melting point. The melting point is experimentally determined in a specific temperature range, which can help identify and purify the substance.
    Solubility is also a key physical property. 4-Hydrazinopyridine hydrochloride has a certain solubility in water, because it contains polar groups, it can form interactions with water molecules. In common organic solvents, the solubility varies depending on the properties of the solvent. In polar organic solvents such as methanol and ethanol, the solubility is relatively good; in non-polar organic solvents such as n-hexane, the solubility is poor.
    In addition, 4-hydrazine pyridine hydrochloride is hygroscopic. Because nitrogen atoms in the molecule can form hydrogen bonds with water molecules, it is easy to absorb water in a humid environment, so it is necessary to pay attention to moisture-proof during storage to maintain its chemical stability and purity.
    In addition, the substance has a certain odor. Although it is not pungent and unpleasant, it still has unique odor characteristics. This odor is related to molecular structure and volatility. However, the volatility is weak, and it is not easy to evaporate into the air at room temperature and pressure. Overall, these physical properties of 4-hydrazinopyridine hydrochloride lay the foundation for its application in organic synthesis, drug development, and other fields. According to its physical properties, chemists can rationally design experimental procedures to achieve effective utilization of the substance.
    4-Hydrazinylpyridine is hydrochloride chemically stable?
    The stability of the chemical properties of 4-hydrazinopyridine hydrochloride needs to be studied in detail. The stability of this substance depends on many factors and cannot be generalized.
    According to the theory of chemistry, the structure of 4-hydrazinopyridine hydrochloride is the key to affecting its stability. Among the molecules, the hydrazine group is connected to the pyridine ring, and the salt is hydrochloride. The pyridine ring has a certain aromaticity, which can endow the molecule with a certain stability; however, the hydrazine group contains active nitrogen and hydrogen bonds, which can easily initiate chemical reactions or reduce the stability.
    Environmental factors also have a significant impact on its stability. When the temperature rises, the molecular thermal motion intensifies, and 4-hydrazinopyridine hydrochloride may undergo decomposition, rearrangement and other reactions. In high temperature environments, hydrazine groups may be oxidized, or react with other substances such as addition and substitution, resulting in structural changes and impaired stability.
    Humidity should not be underestimated. Water vapor in the air can make 4-hydrazinopyridine hydrochloride absorb moisture. If the degree of moisture absorption is very high, it may cause moisture decomposition, which in turn affects its chemical properties and stability.
    Lighting conditions should not be ignored. Some light quantum energies are quite high. When 4-hydrazinopyridine hydrochloride is irradiated by light, the molecule absorbs photon energy, electrons transition, and the molecular activity of the excited state increases greatly, which is prone to photochemical reactions, which affects its stability.
    The solvent system also affects its stability. In different solvents, the solubility of 4-hydrazinopyridine hydrochloride varies with the interaction between molecules. Polar solvents or interactions with molecules such as hydrogen bonding change the distribution of molecular electron clouds, which affects the stability.
    Therefore, the stability of 4-hydrazinopyridine hydrochloride is non-absolute, and it is affected by the interaction of structure, temperature, humidity, light, solvent and other factors. In practical application and storage, various factors need to be taken into account to ensure that its chemical properties are relatively stable.
    What is the synthesis method of 4-Hydrazinylpyridine hydrochloride?
    The synthesis of 4-hydrazinopyridine hydrochloride is very important and complex. In the past, many researchers have studied this synthesis method, each with its own ingenuity.
    Usually, one of the methods is to use pyridine as the starting material. After specific reaction conditions, pyridine first interacts with suitable reagents to introduce specific substituents. This process requires strict control of the reaction temperature, time and amount of reagents. For example, in a mild temperature environment, such as between 30 and 50 degrees Celsius, pyridine and carefully selected reagents are mixed in a precise molar ratio, and the reaction is slowly stirred in an inert gas atmosphere for several hours.
    After that, the obtained intermediate product undergoes further transformation. This step often requires the help of a special catalyst to make the reaction proceed in the direction of generating 4-hydrazinopyridine. The choice of catalyst is crucial, depending on the characteristics of the reaction and the properties of the intermediate product. After 4-hydrazinopyridine is formed, it is then reacted with hydrochloric acid to form 4-hydrazinopyridine hydrochloride. This reaction requires attention to the concentration of hydrochloric acid and the rate of addition to prevent overreaction or side reactions.
    Other methods, or starting from other nitrogen-containing compounds, through multiple steps of ingenious reactions to construct pyridine rings, and hydrazine groups are introduced at appropriate stages, and finally the target product is also reacted with hydrochloric acid. However, no matter what method is used, the details of the reaction, such as the choice of solvent and the regulation of pH, need to be carefully considered in order to improve the purity and yield of the product.
    4-Hydrazinylpyridine hydrochloride in storage and transportation
    4-Hydrazinopyridine hydrochloride is a chemical substance. When storing and transporting, many matters must be paid attention to.
    Let's talk about storage first. First, it is necessary to choose a dry place. Because the substance may have moisture absorption properties, if it is in a humid place, it may cause deliquescence, which will affect the quality. Second, it is suitable for storage in a cool place. Because it is heated or reacted, the temperature is too high, or it may cause decomposition and other changes, which will damage its chemical properties. Third, it needs to be sealed and stored. This is to prevent it from coming into contact with gases such as oxygen and carbon dioxide in the air, causing oxidation or other chemical reactions.
    As for transportation, the first heavy packaging. The packaging must be strong and well sealed to prevent leakage during transportation. Second, the transportation environment should also be suitable. Do not leave it in high temperature, humidity or violent vibration. Excessive vibration may cause damage to the package; temperature and humidity discomfort will also damage its quality. Third, transport personnel should be aware of its characteristics and know emergency measures. In case of leakage and other situations, it can be properly disposed of in time to avoid greater harm.
    In short, the storage and transportation of 4-hydrazinopyridine hydrochloride should be treated with caution to ensure its stability and avoid accidents.