4 Fluorothieno 2 3 C Pyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

4-fluorothieno[2,3-c]pyridine-2-carboxylic acid

    Specifications

    HS Code

    467588

    Chemical Formula C8H4FNO2S
    Molar Mass 197.186 g/mol
    Appearance Solid (predicted, actual may vary)
    Solubility In Water Low (expected due to non - polar rings and limited polar groups)
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF (common for such heterocyclic compounds)
    Odor Odorless (predicted, actual may vary)
    Color Colorless to off - white (predicted, actual may vary)

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    General Information
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    Frequently Asked Questions

    As a leading 4-fluorothieno[2,3-c]pyridine-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4-fluorothieno [2,3-c] pyridine-2-carboxylic acid
    4-Fluorothiopheno [2,3-c] pyridine-2-carboxylic acid, an organic compound. Its molecular structure contains a heterocyclic ring formed by fusing thiophene and pyridine, and is connected with a fluorine atom and a carboxyl group at a specific position.
    thiophene ring is a five-membered heterocyclic ring with a conjugated double bond structure, which makes it aromatic to a certain extent. Pyridine ring is a six-membered heterocyclic ring, which is also aromatic. The two fuse to form a unique electron cloud distribution and spatial structure.
    In the structure of thiopheno [2,3-c] pyridine, fluorine atoms are added at the 4th position, and fluorine has strong electronegativity, which can affect the electron cloud density and chemical activity of the molecule. The carboxyl group (-COOH) at the 2nd position is a hydrophilic functional group, which can participate in a variety of chemical reactions, such as ester formation, salt formation, etc.
    This compound may have potential applications in pharmaceutical chemistry, materials science and other fields due to its special structure. In pharmaceutical chemistry, its structure may be modified to obtain molecules with specific biological activities; in materials science, its conjugated structure may endow materials with unique optical and electrical properties.
    What are the main uses of 4-fluorothieno [2,3-c] pyridine-2-carboxylic acid
    4-Fluoro-thiopheno [2,3-c] pyridine-2-carboxylic acid is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of new drugs in the field of medicinal chemistry. Due to the unique biological activity of thiopheno-pyridine structure, it may interact with specific targets in organisms to develop drugs for specific diseases, such as anti-tumor, anti-viral or neurological diseases.
    In the field of materials science, such compounds may be chemically modified to have unique photoelectric properties for the preparation of organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells, etc. The fluorine atoms of this compound can affect the distribution of molecular electron clouds and have a significant effect on the photoelectric properties of materials.
    Furthermore, in the field of pesticide chemistry, it may also show excellent application prospects. With its special chemical structure and activity, new pesticides may be developed to control crop diseases and pests, and due to its unique structure, or high selectivity and environmental friendliness, it can reduce the impact on non-target organisms.
    In summary, 4-fluorothiopheno [2,3-c] pyridine-2-carboxylic acids have potential application value in many fields such as medicine, materials, and pesticides, and are an important object of research in organic synthesis and related fields.
    What are the synthesis methods of 4-fluorothieno [2,3-c] pyridine-2-carboxylic acid
    The synthesis of 4-fluorothiopheno [2,3-c] pyridine-2-carboxylic acid has attracted much attention in the field of organic synthesis. To synthesize this compound, there are several common methods as follows.
    First, thiophenopyridine is used as the starting material. First, thiophenopyridine is introduced into a carboxyl group at a specific position under suitable reaction conditions. This step can be achieved by the classical carboxylation reaction, such as the reaction of halogenated thiophenopyridine with metal carboxylates in the presence of suitable solvents and catalysts, and the introduction of carboxyl groups is achieved through a nucleophilic substitution process. Subsequently, fluorine atoms are introduced at a predetermined position. The introduction of fluorine atoms can be achieved by nucleophilic fluorination reaction, selecting suitable fluorination reagents, and achieving under mild reaction conditions. In this way, through multi-step reaction, the target product 4-fluorothiopheno [2,3-c] pyridine-2-carboxylic acid can be obtained.
    Second, fluorine-containing pyridine derivatives and sulfur-containing compounds can also be used as starting materials. First, fluorine-containing pyridine derivatives and sulfur-containing reagents are cyclized to construct the parent nuclear structure of thiophenopyridine. This cyclization reaction requires strict control of the reaction temperature, time and proportion of reactants to ensure the smooth progress of the cyclization reaction. After the thiophene-pyridine parent nucleus is formed, the carboxylation reaction is carried out, and the carboxyl group is introduced at a specific position to finally synthesize the target product.
    Third, thiophene derivatives and fluoropyridine-2-carboxylic acid derivatives can also be considered as raw materials. First, thiophene derivatives and fluoropyridine-2-carboxylic acid derivatives undergo condensation reaction to construct the basic skeleton of the target molecule. During the reaction process, suitable condensation agents and reaction solvents need to be selected to optimize the reaction conditions to improve the reaction yield. After that, through appropriate modification reactions, the structure of the target molecule is improved to achieve the synthesis of 4-fluorothiopheno [2,3-c] pyridine-2-carboxylic acid.
    The above synthesis methods have their own advantages and disadvantages. In practical applications, the most suitable synthesis path should be selected according to the availability of starting materials, the difficulty of controlling reaction conditions, and cost-effectiveness.
    What are the physical properties of 4-fluorothieno [2,3-c] pyridine-2-carboxylic acid
    4-Fluorothiopheno [2,3-c] pyridine-2-carboxylic acid, the properties of this product are quite specific, let me elaborate.
    Looking at its shape, under normal conditions, it may be in a crystalline state, like finely broken ice crystals, shining, pure and well-formed, with a regular geometric shape, which is the reason for the orderly arrangement of molecules. Its color may be white and yellowish, like morning light sprinkling, slightly yellow, not pure white, but adds a bit of warmth.
    When it comes to the melting boiling point, a specific temperature is required for melting. It seems that the time has not come, stick to the solid state, and when the heat is just right, it will begin to melt into a flowing state. This temperature range is actually the inherent characteristic of this substance and is the key identification for identification. The same is true for the boiling point. Under a specific air pressure, it reaches the boiling point, and the gas escapes.
    In terms of solubility, it may have different performance in common organic solvents. In alcohols, such as ethanol, it may have a certain solubility and can interact with ethanol molecules and dissolve into them, just like a fish entering water, and it will blend seamlessly. In ethers, such as ether, the solubility may be different, or slightly soluble, or insoluble, depending on the strength of the intermolecular force. In water, it is difficult to form a homogeneous solution due to the difference in molecular polarity and water molecule matching, and the solubility may be limited.
    Furthermore, the density of this substance has a unique value compared with common solvents and compounds. Its density is related to its floating and sinking in the mixed system, and it is of great significance in chemical operation, separation and purification.
    4-fluorothiopheno [2,3-c] pyridine-2-carboxylic acid, with its unique physical properties, occupies a place in the field of chemistry, and is a key factor in scientific research and production. It needs to be carefully explored before it can be used.
    What is the market price of 4-fluorothieno [2,3-c] pyridine-2-carboxylic acid
    The market value of 4-fluorothiopheno [2,3-c] pyridine-2-carboxylic acid is not easy to break. This compound may be useful in specific chemical and pharmaceutical research and development fields, but its market value needs to be considered in more ways.
    Looking at the examples of "Tiangong Kaiwu" in the past, the price of the product often depends on its quality, production and requirements. In today's world, if the quality of this compound is excellent and refined, the price may be very high. Its appearance is also heavy. If the preparation method is complicated, the materials used are scarce, resulting in low output, and the price will tend to increase. Furthermore, the amount of demand is also the key. If a pharmaceutical company is in urgent need of developing new drugs, the supply is less and the demand is more, and the price will rise.
    However, I do not have detailed transaction records, nor do I know the current market for chemical raw materials. It is difficult to determine the price. Or consult a merchant specializing in chemical product trading, or check the trading platform of chemical materials, to get a closer price. And the price varies with the market and time. It needs to be explored in real time to know its current value.