4 Ethylpyridine
pyridine pyrrole pyrazine piperidine piperazine

4-ethylpyridine

    Specifications

    HS Code

    626930

    Name 4 - ethylpyridine
    Molecular Formula C7H9N
    Molar Mass 107.15 g/mol
    Appearance Colorless to light yellow liquid
    Odor Pyridine - like odor
    Density 0.944 g/cm³ (at 20 °C)
    Boiling Point 168 - 170 °C
    Melting Point -43 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 57 °C
    Refractive Index 1.504 (at 20 °C)

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    Frequently Asked Questions

    As a leading 4-ethylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-ethylpyridine?
    4-Ethylpyridine is also an organic compound. It has a pyridine ring and its side chain contains ethyl. The chemical properties of this substance are very interesting, try to explain it in detail.
    As far as its alkalinity is concerned, the pyridine ring has nitrogen atoms and lone pairs of electrons, so it is basic. However, it is weaker than aliphatic amines, and the lone pairs of electrons of nitrogen atoms in the pyridine ring participate in the conjugation system of the ring, which reduces the density of the electron cloud and the ability to accept protons. It can form salts in acids, which is a sign of its alkalinity.
    Its nucleophilic substitution reaction is also characteristic. The electron cloud density on the pyridine ring is uneven, the electron cloud density of the nitrogen atom is low, and the electrophilic reagents such as halogenated hydrocarbons are easy to attack this part. When suitable reagents are available, nucleophilic substitution can occur, and new groups can be introduced into the pyridine ring.
    Re-discussion of its oxidation reaction. The ethyl group of the side chain can be oxidized. If treated with a strong oxidant such as potassium permanganate, the ethyl group can be gradually oxidized to a carboxyl group. This change is also heavy in organic synthesis.
    As for its physical properties, 4-ethylpyridine is a liquid with a special odor, slightly soluble in water, and easily soluble in organic solvents such as ethanol and ether. This is due to the interaction between molecular polarity and solvents. < Br >
    4-ethylpyridine is widely used in the field of organic synthesis. It can be used as an intermediate. With its chemical properties, complex organic molecules can be constructed through various reactions, and it has important applications in drugs, materials and many other aspects.
    What are the physical properties of 4-ethylpyridine?
    4-Ethylpyridine, that is, 4-ethylpyridine, is an organic compound. Its physical properties are unique and are described in detail by you.
    Looking at its properties, under room temperature and pressure, 4-ethylpyridine is a colorless to light yellow liquid, clear and translucent, like Yingying autumn water. Its smell is special, with a strong irritating and pyridine-like smell, pungent smell, and you can feel its unique smell from a distance.
    When it comes to melting point, the melting point of 4-ethylpyridine is quite low, about -43 ° C. This low temperature melting point makes it difficult to solidify in room temperature environment, and always maintains a liquid state.
    In terms of boiling point, it is about 168-170 ° C. When the temperature rises to this value, 4-ethylpyridine converts from liquid to gaseous state and rises.
    Density is also one of its important physical properties, about 0.925 g/cm ³, which is slightly smaller than that of water. If mixed with water, it will float on the water surface.
    Solubility is also worth mentioning. 4-ethylpyridine is soluble in many organic solvents, such as ethanol and ether, just like fish get water, and is inseparable. However, its solubility in water is limited, and it can only be slightly soluble, just like oil floats in water and is difficult to integrate. < Br >
    4-ethylpyridine has a certain degree of volatility, which can evaporate slowly in the air, and its vapor diffuses in the surrounding space. And because it is a liquid, it has good fluidity, and it flows when poured, just like smart water.
    These physical properties are of great significance in many fields such as organic synthesis, medicine and chemical industry, and are the key to its extraction, separation, storage and application.
    In which fields is 4-ethylpyridine used?
    4-Ethylpyridine is an organic compound. It has applications in various fields, as detailed below.
    In the field of medicinal chemistry, 4-ethylpyridine is often a key intermediate for the synthesis of medicine. Due to its special chemical structure, it can participate in many organic reactions and help build complex drug molecular structures. If synthesizing compounds with specific biological activities, 4-ethylpyridine can introduce suitable substituents to adjust the pharmacological properties of the drug, such as enhancing the affinity between the drug and the target, improving its bioavailability, or improving its metabolic stability, etc., and then provide an important raw material basis for the development of new drugs.
    In the field of materials science, 4-ethylpyridine also has outstanding performance. First, it can be used to prepare functional polymer materials. By polymerizing with other monomers, it is introduced into the main chain or side chain of the polymer to endow the material with specific properties, such as improving the solubility, thermal stability, and electrical properties of the material. Second, when preparing some special coating materials, 4-ethylpyridine can be used as an additive to adjust the surface properties of the coating, enhance the adhesion between the coating and the substrate, or endow the coating with special functions such as antibacterial and corrosion resistance.
    Furthermore, in the field of organic synthesis chemistry, 4-ethylpyridine is a commonly used organic base. Its alkalinity is moderate and it can play an important role in many organic reactions, such as catalytic esterification and condensation reactions. Compared with other organic bases, 4-ethylpyridine has a unique spatial barrier and electronic effect, which can affect the rate and selectivity of the reaction, making the reaction more efficient and specific, so it is favored by organic synthesis chemists.
    In addition, in analytical chemistry, 4-ethylpyridine can act as an analytical reagent. Because of its special recognition ability or complexation of certain substances, it can be used to detect the presence of specific compounds or determine their content, providing an effective means for chemical analysis.
    In summary, 4-ethylpyridine has shown important application value in many fields such as medicine, materials, organic synthesis and analysis, and is an indispensable and important compound in the field of organic chemistry.
    What is the synthesis method of 4-ethylpyridine?
    4-Ethylpyridine is 4-ethylpyridine, and its synthesis method is as follows:
    In the ancient method, in order to make 4-ethylpyridine, pyridine is first taken as the base material. Pyridine is a nitrogen-containing six-membered heterocyclic compound with unique properties. Pyridine and halogenated ethane are used as raw materials, and the two react nucleophilically in a specific reaction environment. In halogenated ethane, the halogen atom is quite active and vulnerable to the nucleophilic attack of pyridine nitrogen atoms.
    When reacting, a suitable solvent needs to be prepared to help the reactants mix evenly and promote the reaction. Common solvents, such as ethanol and dichloromethane, can be used. At the same time, the temperature and pressure of the reaction need to be controlled. If the temperature is too high, side reactions are prone to occur; if the temperature is too low, the reaction rate is slow. Usually, the reaction temperature may be set in a moderate range, such as between 40 and 80 degrees Celsius. The pressure is maintained at or slightly above normal pressure.
    Under this condition, the nitrogen atom of the pyridine nucleophilically attacks the carbon atom connected to the halogen atom of the halogenated ethane, and the halogen atom leaves, thus forming 4-ethylpyridine. However, this reaction is often accompanied by the formation of impurities, so the reaction is completed, and it needs to be separated and purified. 4-ethylpyridine can be separated from the reaction mixture by distillation, using the difference in the boiling point of each component. Extraction can also be used to select a suitable extractant to enrich 4-ethylpyridine in a specific phase to separate it from impurities. In this way, pure 4-ethylpyridine can be obtained.
    What is the market outlook for 4-ethylpyridine?
    4-Ethylpyridine is an organic compound with the Chinese name 4-ethylpyridine. Its market prospects are as follows:
    In the field of chemical synthesis, 4-ethylpyridine plays a key role. Due to its unique structure of pyridine ring and ethyl group, it can be used as a key intermediate in the synthesis of many fine chemicals. For example, in the pharmaceutical industry, it can be converted into bioactive compounds through specific chemical reactions for the creation of new drugs, such as antibacterial and anti-inflammatory drugs. With the increasing demand for novel structural compounds in pharmaceutical research and development, the demand for 4-ethylpyridine as an intermediate is expected to rise.
    In the field of materials science, it has also emerged. It can participate in the preparation of polymer materials with special properties, and by polymerizing with other monomers, the materials are endowed with properties such as better solubility and thermal stability. With the increasing demand for high-performance materials in the high-tech industry, the application of 4-ethylpyridine in the material synthesis process may expand, and the market demand will also rise.
    However, its market development also faces challenges. From a production perspective, the synthesis process of 4-ethylpyridine may be complicated and costly, which may limit its large-scale production and marketing activities. Furthermore, environmental protection requirements are becoming stricter. If the production process has high pollution and high energy consumption problems, enterprises must invest more resources in environmental protection treatment, increasing production costs and affecting market competitiveness.
    But in general, with the progress of science and technology and the development of industry, the understanding and application development of the unique properties of 4-ethylpyridine will continue to deepen. If the synthesis process problems can be overcome, the cost can be reduced, and the environmental protection requirements can be met, the market prospect of 4-ethylpyridine is quite broad, and it will be more widely used in chemical, pharmaceutical, materials and other fields, and the market scale is expected to continue to expand.