4 Ethoxy 3 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

4-Ethoxy-3-nitropyridine

    Specifications

    HS Code

    680774

    Chemical Formula C7H8N2O3
    Appearance Solid (usually a yellow - colored solid)
    Odor Typically has a faint, characteristic organic odor
    Melting Point 105 - 107 °C
    Boiling Point Decomposes before boiling under normal pressure
    Solubility In Water Poorly soluble in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Density Approx. 1.28 g/cm³
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents

    As an accredited 4-Ethoxy-3-nitropyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 4-Ethoxy-3-nitropyridine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 4-Ethoxy-3-nitropyridine in China?
    As a trusted 4-Ethoxy-3-nitropyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Ethoxy-3-nitropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-ethoxy-3-nitropyridine?
    4-Ethyl-3-hydroxypyridine is a key intermediate in organic synthesis and has a wide range of uses in many fields such as medicinal chemistry and materials science.
    In the field of medicinal chemistry, it can be used as an important building block for the construction of many active drug molecules. Due to its unique chemical structure and activity check point, it can participate in a variety of chemical reactions, and ingeniously designed and modified to synthesize compounds with specific pharmacological activities. For example, in the development of some drugs with antibacterial and anti-inflammatory properties, 4-ethyl-3-hydroxypyridine can interact with specific targets to exert corresponding pharmacological effects. Taking a new antimicrobial drug as an example, the researchers used 4-ethyl-3-hydroxypyridine as the starting material, introduced a specific functional group through a multi-step reaction, and successfully synthesized a drug molecule that has a significant inhibitory effect on specific drug-resistant bacteria.
    In the field of materials science, 4-ethyl-3-hydroxypyridine can be used to prepare functional materials. Because of its hydroxyl and pyridine ring structure, it can impart unique electrical, optical or thermal properties to the material. For example, when preparing some organic optoelectronic materials, 4-ethyl-3-hydroxypyridine is introduced into the main chain or side chain of the polymer, which can regulate the charge transport performance and luminous efficiency of the material, thereby improving the performance of optoelectronic devices such as organic Light Emitting Diodes (OLEDs).
    In addition, in the synthesis of fine chemical products, 4-ethyl-3-hydroxypyridine is also indispensable. It can be used to synthesize special fragrances, dyes and auxiliaries. For example, in a high-end fragrance formula, 4-ethyl-3-hydroxypyridine is converted into a compound with a unique aroma through a specific reaction, adding a unique flavor to the fragrance. In conclusion, 4-ethyl-3-hydroxypyridine has become an important cornerstone of chemical synthesis and Product Research & Development in many fields due to its own structural characteristics.
    What are the synthesis methods of 4-ethoxy-3-nitropyridine?
    There are several methods for the synthesis of 4-ethyl-3-hydroxypyridine in ancient times.
    First, the corresponding pyridine derivative can be used as the starting material and prepared through a specific substitution reaction. First, take a suitable pyridine substrate, place it in a suitable reaction vessel, and use a specific reagent to perform a substitution reaction under precisely controlled temperature, pressure and reaction time. This process requires precise control of the reaction conditions. Due to the subtle differences in the reaction conditions, the yield and purity of the product may vary.
    Second, through the construction strategy of nitrogen-containing heterocyclic compounds. The choice of appropriate nitrogen-containing raw materials and compounds with specific functional groups is obtained by cyclization under the action of suitable catalysts. The choice of this catalyst is crucial, and its activity and selectivity have a great impact on the reaction process and product structure. And the cyclization reaction conditions also need to be finely adjusted, such as the type of reaction solvent and the high or low reaction temperature, which are all related to the quality of the final product.
    Third, it can be extracted from natural products or obtained by biosynthesis. In some natural plants or microorganisms, or precursors containing such compounds, it is converted into 4-ethyl-3-hydroxypyridine through modern biotechnology, such as fermentation engineering, enzyme catalysis, etc. However, this method requires in-depth understanding of the biological system, and the biosynthetic process is susceptible to interference from many factors, such as medium composition, culture conditions, etc.
    The above methods have their own advantages and disadvantages. In practical application, it is necessary to weigh and choose the most suitable synthetic method according to specific needs, such as product purity, production cost, reaction scale and other factors.
    What are the physical properties of 4-ethoxy-3-nitropyridine?
    4-Ethyl-3-furanyl ketone, this is an organic compound with special physical and chemical properties. It is colorless to light yellow liquid, and has a slightly fragrant smell at room temperature and pressure.
    Looking at its physical properties, the boiling point is about a certain range, and the specific value varies according to the experimental conditions, but it is roughly in a specific range. This property makes it possible to operate by distillation when separating and purifying. Its melting point also has corresponding values, which determine its solid-liquid transformation at a specific temperature. In addition, the density is also a fixed value, which is related to its distribution in solution or mixed system.
    Discussing chemical properties, the furan ring and ketone group in this compound give it unique reactivity. Ketone groups can undergo many reactions, such as addition reactions with nucleophiles, such as the interaction of Grignard reagents with them, which can form new carbon-carbon bonds. This is a common means to build complex structures in organic synthesis. And it can participate in redox reactions, oxidized to corresponding carboxylic acids, or reduced to alcohols. Furan rings are also non-inert. Although they are aromatic, they can perform electrophilic substitution reactions under specific conditions, introducing other functional groups into the ring to expand the derivatization path of compounds. The physical and chemical properties of 4-ethyl-3-furanone provide a foundation for applications in organic synthesis, fragrance preparation, and other fields. Chemists can design and implement various organic synthesis routes according to their properties to obtain compounds with specific functions and structures.
    What are the precautions for 4-ethoxy-3-nitropyridine during storage?
    4-Ethyl-3-hydroxyquinoline needs to pay attention to many key matters during storage.
    First choice of environment. It should be placed in a cool and dry place, away from heat sources and open flames. Due to its chemical properties, it can be heated or exposed to open flames, or cause the risk of combustion or even explosion, causing damage to personnel and property.
    The second is the sealing of the package. Make sure that the package is intact and tightly sealed. If the package is damaged, the outside air, moisture, etc. are easy to come into contact with it, or cause it to oxidize and deliquescence, which affects the quality and performance.
    Furthermore, avoid mixing with incompatible substances. It is necessary to know its chemical properties in detail, and keep away from oxidizing and reducing substances and acids and alkalis. For example, strong oxidants or violent reactions with them endanger storage safety.
    In addition, the storage area should be well ventilated. If the ventilation is not good, the volatile gas may accumulate, which not only pollutes the environment, but also easily causes danger when it reaches a certain concentration.
    At the same time, it is necessary to do a good job in marking management. Clearly mark the name, specifications, production date, shelf life and other key information, which is easy to identify and manage, and is conducive to following the principle of "first in, first out", giving priority to the use of early products to prevent overdue deterioration.
    Finally, the storage place should be equipped with corresponding fire and emergency treatment equipment. Such as fire extinguishers, sand, etc., in the event of an emergency, they can respond promptly to reduce losses.
    What are the effects of 4-ethoxy-3-nitropyridine on the environment?
    The impact of 4-ethyl-3-hydroxyquinoline on its environment is actually related to many aspects.
    If this compound accidentally flows into rivers, lakes and seas in the natural water environment, it may have a significant impact on aquatic organisms due to its structural characteristics. Aquatic plants may be disturbed by photosynthesis, and their internal physiological and metabolic processes may be disrupted. For example, it may interfere with pigment synthesis in plant cells, causing aquatic plants to change color, slow down growth, and even wither and die. For aquatic animals, 4-ethyl-3-hydroxyquinoline may affect their nervous system. The perception, movement and reproduction behavior of aquatic animals may be abnormal, such as abnormal swimming posture of fish, reduced reproduction rate, and declining larval survival rate. In the long run, the balance of aquatic ecosystems will be seriously damaged.
    In the soil environment, if this substance accumulates, it will affect the soil microbial community. Beneficial microorganisms in the soil, such as nitrogen-fixing bacteria and phosphorus-solubilizing bacteria, are active or inhibited. As a result, the fertility status of the soil changes, affecting the absorption of nutrients by plants. Plant growth and development are hindered, and crop yield and quality will be damaged. Moreover, it may also migrate and transform in the soil, pollute groundwater, and threaten human drinking water safety.
    In the atmospheric environment, although its volatility is relatively low, it may also evaporate into the air under certain conditions, such as high temperature or strong light. This will not only affect air quality, but may also enter the human body through respiration. Once in the human body, 4-ethyl-3-hydroxyquinoline may interact with biological macromolecules in human cells, interfere with normal physiological functions, and pose a potential threat to human health.
    In summary, 4-ethyl-3-hydroxyquinoline has a wide range and complex impact on the environment. Whether it is water, soil or atmospheric environment, it may be affected by its negative effects. Therefore, its use and emissions should be strictly controlled.