4-Chloropyridine-sulphonamide

4-Chloropyridine-sulfonamide is one of the organic compounds. It has a wide range of uses and has important applications in the fields of medicine, pesticides and materials science.
In the field of medicine, this compound is often used as a key intermediate in the synthesis of many drugs. Due to its unique chemical structure, it can endow drugs with specific biological activities. For example, by modifying its structure, drugs with antibacterial, anti-inflammatory or anti-tumor activities can be prepared. It can interact with specific targets in organisms and interfere with the physiological processes of pathogens or tumor cells, thus exerting therapeutic effects.
In terms of pesticides, 4-chloropyridine-sulfonamide can be used to create new pesticides. Such pesticides are often highly efficient, low toxic and environmentally friendly. They can act on the nervous system, respiratory system or growth and development-related mechanisms of pests to achieve effective prevention and control of pests, while reducing the adverse effects on non-target organisms and the environment, contributing to sustainable agricultural development.
In the field of materials science, this compound can also play an important role. Or it can be used to synthesize polymer materials with special properties, such as materials with good electrical conductivity, optical properties or thermal stability. By introducing it into the polymer structure, the material can be endowed with unique functions, which can be used in electronic devices, optical instruments and other fields to meet the needs of modern technology for high-performance materials.
In summary, 4-chloropyridine-sulfonamide has shown significant value in many important fields due to its unique chemical properties, which is of great significance for promoting the development of medicine, agriculture and materials science.

4-Chloropyridine-sulfonamide is one of the organic compounds. Its physical properties are quite unique, let me tell you one by one.
Looking at its morphology, at room temperature, it is mostly white to white crystalline powder, with fine texture, as far as the eye can see, quite pure. This morphology is conducive to its storage and use, and in many chemical reactions, it is also convenient for it to mix evenly with other substances, thereby promoting the smooth progress of the reaction.
As for the melting point, 4-chloropyridine-sulfonamide has a specific value. This melting point characteristic is not only an important basis for identifying the substance, but also has great significance in its preparation and purification process. By precisely controlling the temperature, the phase transition occurs near the melting point, which can effectively separate impurities and improve their purity.
In terms of solubility, 4-chloropyridine-sulfonamide exhibits certain solubility in organic solvents. Common organic solvents such as ethanol and acetone can be moderately dissolved. However, in water, its solubility is relatively limited. This difference in solubility is of great significance for the selection of suitable reaction media and separation methods in chemical production and laboratory operations. For example, if the relevant reaction is to be carried out efficiently in a homogeneous system, it is necessary to select a suitable solvent according to its solubility.
In addition, the density of 4-chloropyridine-sulfonamide is also one of the key characteristics of its physical properties. Although the specific value varies depending on the precise measurement conditions, its density characteristics are related to its physical behavior in different environments, such as the distribution state in the mixed system.
In summary, the physical properties of 4-chloropyridine-sulfonamide, from morphology, melting point, solubility to density, are all related and meaningful, and are indispensable factors in many fields such as organic synthesis and drug development.

4-Chloropyridine-sulfonamide is one of the organic compounds. Its properties are related to the characteristics of chemistry and are of great value for investigation.
On its physical properties, under normal conditions, it may be in the shape of a solid state, white or nearly white in color, powdered or crystalline, depending on the degree of refinement. Melting point, due to intermolecular forces, has a specific value, which is an important indicator of its purity. Its solubility in water is not very good. Due to the molecular structure, although sulfonamide groups can form hydrogen bonds with water, chloropyridine is partially hydrophobic, and the two-phase action results in limited dissolution in water. In organic solvents, such as ethanol and acetone, the solubility is slightly better. Due to the principle of similar miscibility, the molecules of organic solvents are adapted to the forces between 4-chloropyridine-sulfonamide molecules.
As for chemical properties, it is very active. Above the pyridine ring at the chlorine atom, the activity of the chlorine atom is greatly increased due to the particularity of the electron cloud distribution of the pyridine ring. It can react with nucleophiles. Nucleophiles such as alcohols and amines can attack the carbon position attached to the chlorine atom, and the chlorine atom leaves to form new compounds. Sulfonamide groups are also active, and hydrogen on the nitrogen atom has a certain acidity, which can react with bases to form corresponding salts. Sulfonamide groups can participate in many condensation reactions, and can form new carbon-nitrogen or carbon-oxygen bonds under suitable conditions with aldehyde and ketone compounds, and derive a variety of compounds. This compound has a wide range of uses in the field of organic synthesis, and can be a key intermediate for the creation of medicines and pesticides. With its activity, it can construct complex and specific biological molecular structures, which make great contributions to human health and agricultural protection.

The synthesis of 4-chloropyridine-sulfonamide is a crucial issue in the field of organic synthesis. The synthesis steps are complicated and require delicate methods and careful operation to achieve it.
At the beginning, pyridine is often used as the initial raw material. Pyridine has a unique cyclic structure and can be a key skeleton in the synthesis reaction. Chlorination of pyridine can introduce chlorine atoms at specific positions in the pyridine ring. This step requires careful selection of reaction conditions and reagents. Usually, appropriate chlorination reagents, such as chlorine-containing halogenating agents, are used at suitable temperatures and in the presence of catalysts to precisely replace the hydrogen atoms on the pyridine ring to obtain 4-chloropyridine. In this process, temperature, catalyst type and dosage all have a great influence on the yield and selectivity of the reaction.
After 4-chloropyridine is obtained, the sulfonamidation reaction is continued. This step requires reagents containing sulfonyl groups, such as sulfonyl chloride compounds, to react with 4-chloropyridine. Under the catalytic action of bases, the sulfonyl groups are connected to the pyridine ring to form a sulfonamide structure. The type and dosage of bases need to be carefully controlled. If the amount of base is too much or too little, the reaction by-products may increase, or the reaction rate is too slow and the yield is low.
During the synthesis process, the conditions of each step of the reaction need to be precisely controlled. The temperature, the length of the reaction time, the purity and dosage of the reagent are all important factors affecting the purity and yield of the product. And after each step of the reaction, appropriate separation and purification operations, such as extraction, distillation, recrystallization, etc., need to be carried out to remove the residual reagents and by-products in the reaction system to obtain pure 4-chloropyridine-sulfonamide.
Synthesis of 4-chloropyridine-sulfonamide requires each step of the reaction, according to the chemical principle, orchestrate the reaction path, strictly control the reaction conditions, and fine operation to achieve the synthesis goal of high efficiency and high purity.

4-Chloropyridine-sulfonamide is in the market, and its price is difficult to determine. The price of this product often changes for many reasons.
First, the cost of production is due to factors. If the price of raw materials is high, or the production process is expensive, the price of the finished product will be high. If you want to get pure 4-chloropyridine-sulfonamide, the raw materials required may need to be refined finely, which increases its cost, and the price will also rise.
Second, the situation of demand and supply also affects its price. If there are many people in the market, and the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price will fall. For example, if there is a new factory mass production, which greatly increases the supply in the market, the price may decline.
Third, the rules of trade relocation and tax administration also have an impact. In different places, the rules of trade and the severity of taxes can make the price different. If it is heavily taxed or complies with strict trade regulations, its price will be affected by it.
As far as common sense is concerned, the price of this product per gram may be between a few yuan and a few dozen yuan. However, this is only a rough number. The actual transaction may vary depending on the quantity and quality. If the quantity is large, there may be room for bargaining, and the price can be slightly reduced; if the quality is high, the price will be higher. Therefore, in order to know the exact price, we must carefully examine the market conditions and negotiate with various suppliers before we can obtain an accurate number.