4-CHLOROPYRIDINE-3-CARBOXYLIC ACID

4-Chloropyridine-3-carboxylic acid, an organic compound, has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to synthesize various bioactive compounds. In the development process of many drugs, 4-chloropyridine-3-carboxylic acid can participate in many reactions due to its unique chemical structure, laying the foundation for the construction of complex drug molecular structures.
In the field of pesticide chemistry, it also has important uses. It can be used as a raw material for the synthesis of specific pesticides, helping to prepare pesticide products with high insecticidal, bactericidal or herbicidal properties, and plays a key role in the control of pests and diseases and weeds in agricultural production.
In the field of materials science, the synthesis of some functional materials also involves 4-chloropyridine-3-carboxylic acids. By introducing it into the material structure through specific chemical reactions, it can endow the material with unique properties such as special optical, electrical or mechanical properties, thereby expanding the application range of the material.
In addition, in the study of organic synthetic chemistry, it is a commonly used starting material or intermediate, providing rich possibilities for organic chemists to carry out new reaction exploration, molecular structure modification and construction, promoting the continuous development of organic synthetic chemistry, and helping to synthesize more organic compounds with novel structures and excellent properties.

4-Chloropyridine-3-carboxylic acid, its physical properties are as follows:
This substance is mostly solid at room temperature, but the specific form may vary slightly depending on the preparation process and purity. Its melting point is about [X] ° C, and the melting point is one of the characteristics of the substance. Under certain conditions, the solid-liquid two phases can coexist in equilibrium. In terms of boiling point, it is about [X] ° C in an atmospheric pressure environment. At this temperature, the substance changes from liquid to gaseous state.
Its solubility is quite important. In water, it is slightly soluble. Because its molecular structure contains polar groups, it can interact with water molecules to a certain extent. However, the existence of pyridine rings and chlorine atoms limits its solubility in water. In organic solvents such as ethanol and acetone, the solubility is relatively good, and the polarity and intermolecular force of organic solvents are more suitable for the substance, which is conducive to its dispersion and dissolution.
4-chloropyridine-3-carboxylic acid The appearance is often white to off-white powder or crystalline solid, and the color and morphology are the key characteristics of preliminary identification. Its density is about [X] g/cm ³. This value reflects the mass per unit volume of the substance. In specific production and application scenarios, it is related to the measurement and reaction ratio of the material.
In addition, the stability of the substance is also a consideration of physical properties. Under normal environmental conditions, it has a certain stability. In case of extreme conditions such as high temperature, strong acid and alkali, or reactions such as decomposition and deterioration, it affects its chemical structure and properties. Understanding its physical properties is of important guiding significance for storage, transportation and application to ensure that it maintains its due characteristics and quality in all aspects.

The chemical synthesis method of 4-chloropyridine-3-carboxylic acid has been around for a long time, and it is much more delicate. In the past, many sages have studied the way of organic synthesis diligently to obtain this method.
One of the methods can be started from a pyridine derivative. Select a suitable pyridine substrate and introduce a chlorine atom into the fourth position of the pyridine ring under specific reaction conditions. This step is very crucial. It is necessary to carefully observe the reaction temperature, the ratio of reagents, and the choice of catalysts. Commonly used chlorination reagents, such as chlorine-containing halogenating agents, react with pyridine substrates under the catalysis of suitable catalysts. Either in a mild reaction environment, or requires stronger reaction conditions, depending on the characteristics of the substrate.
Wait for the 4-chloropyridine derivative to be obtained, and then perform a carboxylation reaction. Carbon dioxide can be selected as the carboxyl source. Under the action of a metal catalyst, the 4-chloropyridine derivative is combined with carbon dioxide to introduce carboxyl groups at the 3rd position. In this process, the activity of the metal catalyst, the pH of the reaction system, and the reaction time are all factors that affect the success or failure of the reaction.
There are other methods as well. Or start from easily available raw materials and gradually construct the structure of 4-chloropyridine-3-carboxylic acid through multi-step reactions. The pyridine ring is first formed by cyclization reaction, followed by the introduction of chlorine atoms by halogenation reaction, and then the carboxyl group is added to the appropriate position through a specific functional group conversion reaction.
All synthesis methods have their own advantages and disadvantages. It is necessary to choose carefully according to many factors such as the availability of raw materials, the difficulty of reaction, and the purity requirements of the product, so as to achieve twice the result with half the effort and obtain pure 4-chloropyridine-3-carboxylic acid.

What is the price of 4-chloropyridine-3-carboxylic acid in the market? This question is related to the market situation of the business market, but it is not easy to determine its precise price range. Because of the change in price, it is affected by various factors.
First, the supply and demand of the market is the most important. If there are many people who want it, but the supply is small, the price will increase; on the contrary, if the supply exceeds the demand, the price will fall. Second, the price of raw materials for making this product also affects its selling price. If the price of raw materials is high, the cost will increase, and the selling price will increase; if the price of raw materials decreases, the cost will decrease, and the price may also fall. Furthermore, the complexity of the process is related to the difficulty and quantity of production. The more complex the process, the more time-consuming and laborious the production, and the price will not be low; if the process is refined, the production efficiency will increase greatly, and the price may drop.
In addition, the price varies from region to region. Distant places, due to the difference in transportation fees and taxes, the price may be different from nearby places. And different merchants, because of their business strategies and cost control, have different pricing.
In the past, the price often fluctuates in a certain range. If you want to get the current price, it is advisable to consult the chemical raw material suppliers or explore the chemical trading platform to get real-time and accurate prices.

4-Chloropyridine-3-carboxylic acid, this is a chemical substance. Its storage conditions are quite important, related to its quality and stability.
Under normal temperature conditions, it must be placed in a dry place. Because humid gas can easily make the substance damp or cause it to undergo chemical reactions, which will damage its chemical properties.
Furthermore, it should be stored in a cool place to avoid high temperature environment. High temperature is very likely to cause the decomposition of the substance, or accelerate its chemical reaction rate, causing it to deteriorate.
And keep away from fire sources and oxidants. 4-Chloropyridine-3-carboxylic acid may react violently when exposed to an open flame or an oxidizing agent, and even cause an explosion, endangering safety.
When storing, attention should also be paid to sealing. If the sealing is not good, the substance is prone to interact with components in the air, such as oxygen, carbon dioxide, etc., thus affecting its quality.
The storage place should be well ventilated. In this way, once the substance leaks, the harmful gases can be dissipated in time to reduce the harm to the environment and the human body.
For containers containing 4-chloropyridine-3-carboxylic acid, it is also necessary to choose carefully. Materials that can withstand the corrosion of the substance should be used to prevent the leakage of the substance due to damage to the container.
In summary, 4-chloropyridine-3-carboxylic acid should be stored in a suitable container at room temperature, dry, cool, away from fire-source oxidants, sealed and well ventilated, so as to ensure its stability and storage safety.