4-Chloropyridine-2-carboxamide 98%

4-Chloropyridine-2-formamide, with a content of 98%, has a wide range of uses. In the field of medicine, it is often used as a key intermediate. The structure of gainpyridine and amide is common in many drug molecules. 4-chloropyridine-2-formamide can be synthesized by organic synthesis, through substitution, condensation and other reactions, and linked with other active groups to create compounds with specific pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the field of pesticides, it also plays an important role. Due to its unique chemical structure, it can be derived from pesticide ingredients that have inhibitory or killing effects on pests and pathogens. By adjusting its substituents, the activity and selectivity of compounds to specific target organisms can be optimized, the purpose of precise prevention and control of pests and diseases can be achieved, and the effectiveness of pesticides can be improved.
In the field of materials science, 4-chloropyridine-2-formamide is also useful. It can participate in the synthesis of polymer materials, and by introducing pyridine and amide groups, it can endow materials with special optical and electrical properties, or improve the mechanical properties and thermal stability of materials. For example, in the preparation of some functional polymers, it is introduced as a structural unit, so that the polymers exhibit unique physical and chemical properties to meet the special needs of materials in different fields.

At present, it is not easy to know the market price of 4-chloropyridine-2-formamide (98% content). Because the market situation is fickle, it is like the unpredictable situation. In the past, the prices of various medicinal materials and chemicals often varied according to the season, place of origin, and supply and demand.
In the book "Tiangong Kaiwu", everything has changed. This 4-chloropyridine-2-formamide, if in the past, may have been the material required by various workshops and workshops. Its price should follow the supply and demand of the market. If the supply exceeds the demand, the price will fall, like the leaves of autumn, and gradually become cheaper; if the supply exceeds the demand, the price will be like the seedlings of spring, rising steadily.
In today's world, commerce is widespread, and the flow of goods in the four directions is fast. Its price is also subject to foreign products and various decrees. Or due to the distance of the journey, the increase or decrease of taxes, the price changes. And in the chemical industry, new products are produced in large numbers, and technology changes, or the price of this material fluctuates. Therefore, in order to know its market price, when you widely observe the business conditions of the four parties, consult the experts in the industry, and carefully examine the current supply and demand, you can get the approximate number. It is difficult to say the exact price in a word.

The production process of 4-chloropyridine-2-formamide (content 98%) is quite delicate. In the past, the method was originally based on pyridine, which was a cyclic nitrogen-containing organic compound with unique properties. After halogenation, the chlorine atom is cleverly connected to the 4 positions of the pyridine ring. During halogenation, the choice of halogenating agent, temperature control, and timing are all key. The halogenating agent used, either chlorine gas or chlorine-containing reagent, is selected according to its characteristics and the needs of the reaction. The control of temperature is related to the reaction rate and the purity of the product, and should not be careless. The adjustment of time also affects the completeness of the reaction. < Br >
Then, the formamide group is introduced into the second position of the pyridine ring by the method of amidation. When amidation, choose a suitable amidation reagent, such as a formamide compound, or a reagent containing carbonyl and amino groups. In the reaction system, the properties of the solvent and the effectiveness of the catalyst also affect the reaction process. The solvent needs to be compatible with the reactants and has the ability to promote the reaction; the catalyst can accelerate the reaction and improve the yield.
After two steps of halogenation and amidation, the crude product is initially produced. However, if you want to obtain a high-quality product with a purity of 98%, you still need to refine it. The method of recrystallization is often used, and the appropriate solvent is selected to dissolve the crude product in the solvent. After cooling and crystallization, the impurities are left in the mother liquor, and the crystal is high-purity 4-chloropyridine-2-formamide. Or column chromatography is used to separate the impurities and products according to the different effects of the compound with the stationary phase and the mobile phase, and finally obtain a high-purity target product.

4-Chloropyridine-2-formamide, with a content of 98%, many matters must be paid attention to during storage and transportation.
This chemical has certain chemical activity. When stored, the first environment is dry. Humid gas can easily cause chemical reactions such as hydrolysis, which can damage its purity and quality. Therefore, the warehouse should be well ventilated and the humidity should be kept at a low level to prevent the risk of moisture decomposition.
Furthermore, temperature is also crucial. High temperature may cause changes in its chemical properties, or cause undesirable conditions such as decomposition. It should be stored in a cool place, protected from direct sunlight, and the temperature should be maintained within a specific range. The specific value depends on its chemical properties and relevant specifications.
During transportation, the packaging must be solid and reliable. Due to its chemical activity, a little carelessness may cause leakage if the packaging is damaged, causing potential safety hazards. The packaging materials used should be resistant to chemical corrosion and ensure a tight seal.
In addition, the transportation vehicle should also be clean and free of other chemical impurities to prevent cross-reaction with it. At the same time, the transportation personnel must be professionally trained to be familiar with the characteristics of this chemical and emergency treatment methods. In case of emergencies, they can properly deal with it to ensure transportation safety and avoid harm to personnel and the environment.

4-Chloropyridine-2-formamide, content 98%, its Quality Standard has the following numbers:
bear the brunt, related to the appearance, this product should be white to off-white crystalline powder, viewing should be pure without variegation, no foreign matter, such as good jade flawless, uniform color, fine powder and no agglomeration appearance.
When it comes to purity, if the standard is 98%, it needs to be verified by accurate analytical methods. Commonly used high performance liquid chromatography (HPLC) determination, the purity measured by the normalization method of the main peak area shall not be less than 98.0%, and the total area of the impurity peak shall not exceed 2.0%, so as to meet its nominal purity. Each impurity peak also needs to be strictly controlled, and the specific impurity content has a clear limit that cannot be exceeded.
Melting point is also a key indicator. After determination, the melting point of 4-chloropyridine-2-formamide should be within a specific range, usually [specific melting point range]. When measuring, it is necessary to follow the standard melting point measurement method to ensure uniform heating, accurately record the initial melting and full melting temperature, so as to determine the characteristics of its physical state transformation, which is related to the purity of the substance and the integrity of the crystalline structure.
Moisture content cannot be ignored. Due to its chemical properties, too much moisture or deterioration and other drawbacks. Therefore, it is necessary to use an appropriate method, such as the Karl Fischer method, to determine the moisture content should not exceed the [specific moisture limit] to ensure its dryness and maintain chemical stability.
The amount of incandescent residue is also standard. After high temperature incandescence, the residual residue shall not exceed the [specific incandescent residue limit], which can detect the amount of inorganic impurities in it and reflect the effect of removing impurities in the production process.
In addition, the content of heavy metals also needs to be strictly controlled. With appropriate methods of detection, the content of heavy metals (measured as lead) shall not exceed the [specific heavy metal limit], to avoid the introduction of harmful impurities, to ensure product quality and safety, and to have no potential harm in subsequent applications.
These Quality Standards are designed to ensure that 4-chloropyridine-2-formamide is of high quality and suitable for various applications.