4-CHLORO-PYRIDINE-2-CARBONITRILE

4-Chloropyridine-2-formonitrile has a wide range of uses and is a key raw material in the field of organic synthesis.
Looking at the field of medicinal chemistry, it is often the cornerstone of the creation of new drugs. Due to the unique chemical properties of pyridine and nitrile groups, various functional groups can be connected through various reactions, and then compounds with specific pharmacological activities can be constructed. For example, when developing antibacterial and anti-inflammatory drugs, 4-chloropyridine-2-formonitrile can be used as a starting material, which can be converted into drug molecules with targeted therapeutic effects through carefully designed reaction steps.
It also has important uses in the field of materials science. Can participate in the preparation of special polymer materials, by copolymerizing with other monomers, giving the material unique properties, such as improved heat resistance, mechanical strength, etc. Because the nitrile group can undergo polymerization reaction, combine with suitable monomers, or form polymers with special structures and functions, it is used in aerospace, electronic devices and other fields that require strict material properties.
Furthermore, in pesticide chemistry, 4-chloropyridine-2-formonitrile also plays an important role. It can be used as an intermediate for the synthesis of high-efficiency and low-toxicity pesticides. With its structural characteristics, it can create pesticide products with high selectivity, strong lethality to specific pests, and environmental friendliness. It helps agricultural production to control pests and diseases and ensure crop harvests.

4 - CHLORO - PYRIDINE - 2 - CARBONITRILE is an organic compound. Its physical properties are crucial and it is widely used in many chemical fields.
This compound is mostly solid at room temperature. Due to the strong intermolecular force, it has a certain melting point. However, the exact melting point value will vary according to the preparation process and purity, and it is roughly in a specific temperature range.
Looking at its solubility, 4 - CHLORO - PYRIDINE - 2 - CARBONITRILE exhibits good solubility in organic solvents, such as common ethanol and acetone. This is because the molecular structure of the compound is similar to that of organic solvents. In water, its solubility is relatively weak, due to poor matching between the polarity of water molecules and the molecular polarity of the compound.
Furthermore, the density of 4-CHLORO-PYRIDINE-2-CARBONITRILE is also an important physical property. Compared with water, its density is unique. The specific value depends on accurate measurement, but it is generally consistent with the density range of common organic solids.
Its appearance is often white or off-white crystalline powder, which not only helps to visually identify, but also reflects its crystal structure and molecular arrangement.
In chemical analysis, its physical properties have a great impact on the separation, purification and identification process. Melting point determination can help determine purity, and solubility characteristics can provide a basis for selecting appropriate solvents and separation methods.

The synthesis of 4-chloro-pyridine-2-formonitrile is an important matter in chemical synthesis. This method is described to help those who seek knowledge.
One method can be started with 4-chloro-2-methylpyridine. First, the methyl of 4-chloro-2-methylpyridine is oxidized to a carboxyl group under suitable reaction conditions with a suitable oxidant, such as potassium permanganate, etc., to obtain 4-chloro-pyridine-2-formic acid. This process requires attention to the reaction temperature, reaction time and the amount of oxidant. If the temperature is too high, or side reactions occur, the product is impure; if the time is too short, the oxidation is not complete.
After 4-chloro-pyridine-2-carboxylic acid is obtained, it is reacted with ammonia. 4-chloro-pyridine-2-carboxylic acid and excess ammonia are heated in a suitable solvent, such as ethanol, to generate 4-chloro-pyridine-2-formamide. This step requires controlling the heating temperature and reaction time to ensure that the reaction is fully carried out.
4-Chloro-pyridine-2-formamide can be converted into 4-chloro-pyridine-2-formonitrile after being treated with a dehydrating agent, such as phosphorus pentoxide. This dehydration reaction also needs to pay attention to the reaction conditions. The amount of dehydrating agent should be moderate. Too much or too little will affect the yield of the product.
Another method can start from 2-amino-4-chloropyridine. First, the amino group is diazotized with suitable reagents, such as sodium nitrite and hydrochloric acid, to obtain diazonium salts. This diazotization reaction needs to be carried out at low temperature to prevent the decomposition of diazonium salts.
The obtained diazonium salt can be reacted with cyanide reagents such as cuprous cyanide to introduce cyanide groups to generate 4-chloro-pyridine-2-formonitrile. The use of cyanide reagents in this process should be cautious because of its toxicity.
Synthetic methods have their own advantages and disadvantages. In practical applications, the selection needs to be weighed according to factors such as raw material availability, cost, and product purity. In this way, 4-chloro-pyridine-2-formonitrile can be efficiently synthesized.

4-Chloropyridine-2-formonitrile is an organic chemical substance. During storage and transportation, it is necessary to pay attention to many matters to ensure its stability and safety.
First storage environment. It should be placed in a cool, dry and well-ventilated place. This substance is afraid of moisture, and it is easy to deteriorate in a humid environment. Therefore, the humidity in the storage place must be strictly controlled to prevent it from causing chemical reactions due to moisture absorption. And the temperature should not be too high. Adverse changes such as high temperature or decomposition may threaten storage safety.
Times and packaging. It should be packed in a well-sealed container to prevent contact with air. Because of its interaction with components in the air, such as oxygen, water vapor, etc. High-quality packaging materials should have good corrosion resistance to avoid leakage of substances caused by corrosion of the packaging.
Furthermore, when transporting, ensure that the container is stable and avoid collision and vibration. Violent collision, vibration or damage to the package, resulting in leakage of 4-chloropyridine-2-formonitrile. The means of transportation should also be kept clean and dry, and should not be mixed with other substances that may react with it to prevent dangerous accidents.
In addition, operators should strictly abide by the operating procedures and be equipped with necessary protective equipment, such as gloves, goggles, protective clothing, etc. Because of its certain toxicity and irritation, if inadvertent contact may endanger personal safety. < Br >
Storage and transportation of 4-chloropyridine-2-formonitrile, each step is related to safety and quality, and it is necessary to handle it carefully and without any slack to ensure the smooth process.

The market price of 4-chloropyridine-2-formonitrile often changes due to many reasons, and it is difficult to put it in a word.
The market state of the past is that its price fluctuations may be caused by changes in supply and demand, the price of raw materials, the difficulty of the process, and the stability of the current situation. If the demand for this product is strong, but the supply is thin, the price will rise; on the contrary, if the supply exceeds the demand, the price will be depressed. The price of raw materials is also the key. Raw materials are rare, and the price must be high, and the product will be expensive; if the raw materials are abundant, the price will be cheap, and the product will also drop. Furthermore, the preparation process is complicated, the cost will be high, and the price will be high; the process is simple, and the cost will be reduced and the price will < Br >
However, today, its market price is difficult to determine. To know the exact price, you must check the recent market report, or consult the chemical raw material supplier, in order to obtain the exact number of the current market, in order to meet the needs.