4-CHLORO-5-IODO-2-(TRIFLUOROMETHYL)PYRIDINE

4-Chloro-5-iodine-2- (trifluoromethyl) pyridine, this is an organic compound. Its physical properties, let me tell them one by one.
Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, or crystalline solid, depending on the specific purity and environmental conditions. Its smell often has a special organic compound smell, or irritating, but it also varies slightly due to individual olfactory perception.
When it comes to melting point, according to relevant books, the melting point of this compound is about a specific range, but due to the preparation method and impurities, the melting point may fluctuate slightly. Usually between [X] ° C and [X] ° C. At the melting point, the compound gradually melts from a solid state to a liquid state.
The boiling point is also one of its important physical properties. At standard atmospheric pressure, its boiling point is about [X] ° C. When the temperature rises to the boiling point, the compound changes from a liquid state to a gaseous state, and this process requires absorption of a large amount of heat.
As for solubility, this compound exhibits different solubility properties in organic solvents. In common organic solvents, such as dichloromethane, chloroform, ether, etc., it has good solubility and can be miscible with it to form a uniform solution. This is because its molecular structure is compatible with the intermolecular forces of organic solvents. However, in water, its solubility is relatively poor, because its molecular structure contains fluorine, chlorine, iodine and other halogen atoms and trifluoromethyl groups, which makes the polarity of the molecule different from that of water, so it is difficult to dissolve in water.
Density is also a key factor in considering the physical properties of this compound. Its density may be different from that of water, about [X] g/cm ³, and the specific value will also vary slightly due to different purity and measurement conditions. This density characteristic is particularly important when it comes to the separation and mixing of compounds.
In conclusion, the physical properties of 4-chloro-5-iodine-2 - (trifluoromethyl) pyridine are of great significance in the research and application of organic chemistry, related to its preparation, separation, storage, and participation in various chemical reactions.

4-Chloro-5-iodine-2- (trifluoromethyl) pyridine is widely used in the field of organic synthesis. First, it can be used as a pharmaceutical intermediate. The structure of geinpyridine is quite common in many drug molecules. This compound can be introduced into the drug molecular structure through specific reaction modifications to increase its biological activity and improve pharmacokinetic properties. For example, the synthesis of some anti-cancer drugs and anti-infective drugs often relies on this intermediate to build key structural fragments, which help to achieve the effect of drugs on specific targets, and then achieve the purpose of treating diseases.
Second, it also plays an important role in the field of pesticide synthesis. Pyridine compounds often have significant biological activities against pests and pathogens. 4-chloro-5-iodine-2 - (trifluoromethyl) pyridine can be chemically converted to make pesticides, fungicides and other pesticide products. With its unique chemical structure and activity, it can effectively inhibit the growth and development of pests or kill pathogens, ensure the healthy growth of crops, and improve crop yield and quality.
Furthermore, in the field of materials science, this compound also has potential applications. It can be used as a starting material for the construction of functional organic materials. After reacting with other organic or inorganic reagents, materials with special optical and electrical properties are generated. For example, it is used to prepare organic Light Emitting Diode (OLED) materials, or materials with specific adsorption and separation properties, which play an important role in the fields of optoelectronic devices, separation and purification.
Because of its halogen atom and trifluoromethyl group, it endows the molecule with unique physical and chemical properties and provides rich possibilities for various reactions. Chemists can ingeniously modify its structure through nucleophilic substitution, coupling and other reactions, expanding its application range in different fields, making it an indispensable and important compound in organic synthetic chemistry.

The synthesis of 4-chloro-5-iodine-2- (trifluoromethyl) pyridine is an important topic in organic synthetic chemistry. The synthesis path often requires multi-step reactions and careful design to achieve.
The choice of starting materials is related to the success or failure of the synthesis and the efficiency. Common starting materials, or compounds with pyridine structure, are gradually converted into substituents to introduce the target chlorine, iodine and trifluoromethyl.
In the synthesis step, the halogenation reaction is crucial. To introduce chlorine atoms, a suitable chlorination reagent, such as an inorganic compound containing chlorine or an organochlorination reagent, can be selected to chlorinate the pyridine ring at a specific position under appropriate reaction conditions. This reaction requires attention to the reaction temperature, reaction time and the proportion of reactants to prevent excessive chlorination or by-products. There are also methods for introducing
iodine atoms. Iodine substitutes can be used to connect iodine atoms at designated positions in the pyridine ring through a reaction mechanism similar to halogenation. This process also requires precise control of the reaction conditions to ensure that the iodine atoms are replaced in the desired position.
The introduction of trifluoromethyl is relatively complicated. Or use a reagent containing trifluoromethyl to connect trifluoromethyl to the pyridine ring through nucleophilic substitution, free radical reaction, etc. This step requires strict reaction environment, and conditions such as anhydrous and oxygen-free may be necessary to improve the selectivity and yield of the reaction.
After each step of the reaction is completed, the separation and purification of the product are also indispensable. Commonly used separation methods, such as column chromatography, recrystallization, etc., aim to obtain high-purity 4-chloro-5-iodine-2 - (trifluoromethyl) pyridine. This compound has great application potential in the fields of medicine and pesticides, so the exploration and optimization of its synthesis method has always been a hot topic of chemical research.

4-Chloro-5-iodine-2 - (trifluoromethyl) pyridine, when hiding, need to pay more attention.
First, its nature or activity, easy to react with other things. Therefore, it must be placed in a cool, dry and well ventilated place, away from fire and heat sources. Cover high temperature or cause its reaction to intensify, and even risk, such as fire, explosion risk.
Second, this pyridine may be toxic and corrosive. When storing, it must be isolated from oxidants, acids, bases, etc., to prevent interaction and release of poison or corrosion of other substances. When taking it, you should also be careful and wear protective gear to avoid contact with the skin and eyes.
Furthermore, the packaging must be in good condition. If the packaging is damaged, it is easy to leak, which not only pollutes the environment, but also increases the danger. Once leaked, it should be handled according to proper laws, such as collecting it with inert materials, and then disposing of it in compliance.
And because the compound may be harmful to the environment, it should be prevented from entering the environment when storing. And where it is stored, it should be clearly marked, stating the characteristics, hazards and emergency measures of this thing, so that everyone can know it, and in case of an emergency, they can respond calmly, ensuring the safety of people, things and the environment.

The market price of 4-chloro-5-iodine-2- (trifluoromethyl) pyridine often fluctuates due to various reasons. The cost of its raw materials is a key factor affecting the price. If the chlorine, iodine and trifluoromethyl-containing raw materials required for the preparation of this compound are expensive to obtain, or the supply is unstable due to changes in the origin of the raw materials, scarcity of resources, etc., the price of the pyridine compound will be affected by it.
Furthermore, the difficulty of the preparation process is also significantly related to the cost. If the synthesis of this compound requires complicated and delicate steps, strict control of reaction conditions, and expensive catalysts or special reaction equipment, this will push up production costs, which in turn will increase market prices.
The state of market supply and demand also affects its price. If many industries, such as pharmaceutical research and development, pesticide creation, etc., have strong demand for 4-chloro-5-iodine-2 - (trifluoromethyl) pyridine, but the supply is difficult to meet, the price will rise; conversely, if the market demand is weak, the supply exceeds the demand, and the price may decline.
In addition, the number of manufacturers and the competitive situation are also factors. If there are many manufacturers of this compound in the market and the competition is fierce, in order to compete for market share, the manufacturers may win with the price advantage, resulting in a stable or declining price; however, if the manufacturers are rare and form a monopoly, the price may be controlled by them, and it is at a higher level.
As far as the current market is concerned, the price of 4-chloro-5-iodine-2 - (trifluoromethyl) pyridine fluctuates between [X] yuan and [X] yuan per gram, but this is only a rough number. The actual price depends on the specific situation of the current market. The purchaser should carefully observe the market dynamics and compare it with multiple parties to obtain a reasonable price.