4 Chloro 3 Methyl Pyridine 2 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE

    Specifications

    HS Code

    460569

    Chemical Formula C7H5ClN2
    Molar Mass 152.58 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point 93 - 97 °C
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Vapor Pressure Low vapor pressure due to its solid state at room temperature

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    General Information
    Where to Buy 4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE in China?
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    Frequently Asked Questions

    As a leading 4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE?
    4-Chloro-3-methyl-pyridine-2-formonitrile, this is an organic compound. Looking at its structure, it contains chlorine atoms, methyl groups, pyridine rings and formonitrile groups. These groups endow it with unique chemical properties.
    Chlorine atoms are electronegative, which can increase the polarity of molecules and affect their physical and chemical properties. In chemical reactions, chlorine atoms are active and can participate in reactions such as nucleophilic substitution. Methyl groups are power supply groups, which can change the electron cloud distribution of pyridine rings and affect the reactivity and selectivity on the rings. Pyridine rings are aromatic and have certain stability and special reactivity. The carbon-nitrogen triple bond in the methylnitrile group has high reactivity and can participate in a variety of organic synthesis reactions, such as hydrolysis to carboxylic acid, reduction to amine, etc.
    4-chloro-3-methyl-pyridine-2-formonitrile may be used as a key intermediate in the field of organic synthesis for the preparation of drugs, pesticides, materials, etc. Its chemical properties are complex and unique due to the interaction of various groups, providing a broad space for the research and application of organic chemistry.
    What are the main uses of 4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE?
    4-Chloro-3-methyl-pyridine-2-formonitrile is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicine. It can be seen in the synthesis of many drugs. Due to the unique chemical activity of pyridine and nitrile groups, it can be converted into structural units with specific pharmacological activities through various chemical reactions. For example, in the synthesis of some antibacterial drugs, it can contribute to the construction of the core skeleton of drugs, and make significant contributions to improving the antibacterial efficacy of drugs and optimizing the metabolic characteristics of drugs.
    In the field of pesticides, it is also an indispensable raw material. After specific reaction steps, pesticide products such as insecticides and fungicides can be prepared. With its structural characteristics, the prepared pesticides may have the advantages of high efficiency, low toxicity, and environmental friendliness. They play a great role in the prevention and control of crop diseases and pests, and escort the agricultural harvest.
    In the field of materials science, 4-chloro-3-methyl-pyridine-2-formonitrile is also useful. It can participate in the synthesis of functional materials, such as some optoelectronic materials. By polymerizing or reacting with other monomers, the materials are endowed with novel optical and electrical properties, providing an important foundation for the research and development of new display materials and semiconductor materials, and promoting the continuous development of materials science.
    What are 4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE synthesis methods?
    The synthesis of 4-chloro-3-methyl-pyridine-2-formonitrile is a subject of great concern in the field of chemistry. There are several common ways to synthesize this compound.
    One of them can be started from the starting material containing the pyridine ring. Select suitable pyridine derivatives with functional groups that can be substituted at specific positions. For example, 3-methyl-pyridine-2-formonitrile is used as a substrate to introduce chlorine atoms through a halogenation reaction. During this process, careful selection of halogenating reagents such as chlorine gas and sulfoxide chloride is required. At the same time, the reaction conditions, such as reaction temperature, reaction time, and molar ratio of the reactants, are strictly controlled. The appropriate reaction temperature or in a specific range, and the time also needs to be precisely controlled, so that the reaction can proceed smoothly in the direction of generating the target product, and the yield and purity of the product can be improved.
    Second, the strategy of gradually constructing the pyridine ring can also be adopted. Through multi-step reactions, starting from simple organic compounds, the pyridine ring structure is gradually established, and specific substituents are introduced. For example, small molecule compounds containing nitrogen and carbon are first used to form a pyridine ring skeleton through condensation, cyclization, etc., and then chlorine atoms and methyl groups are introduced at a predetermined position. Although this method is complicated, it can precisely control the position and type of substituents on the pyridine ring, which is helpful to obtain high-purity target products. However, each step of the reaction needs to be carefully optimized to ensure the efficiency and feasibility of the overall synthesis route.
    Furthermore, the synthesis methods of similar compounds reported in the literature can also be referred to, and the structural characteristics of 4-chloro-3-methyl-pyridine-2-formonitrile can be appropriately improved and optimized. For example, by referring to the chlorination reaction conditions of other pyridine compounds, and adjusting the parameters such as reaction reagents, solvents and reaction temperatures according to the spatial structure and electronic effects of the target products, a more suitable synthesis path can be explored.
    There are many methods for synthesizing 4-chloro-3-methyl-pyridine-2-formonitrile. Researchers need to carefully select the appropriate synthesis route according to their own experimental conditions, availability of raw materials, and requirements for product purity and yield, and continuously optimize the reaction conditions to achieve the purpose of efficient synthesis.
    4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE are there any precautions during storage and transportation?
    4-Chloro-3-methyl-pyridine-2-formonitrile is an important intermediate in organic synthesis, and it does require a lot of attention when storing and transporting.
    Store first. This substance needs to be stored in a cool, dry and well-ventilated place. Because it is quite sensitive to heat, high temperature can easily cause decomposition or other chemical reactions, so it is essential to avoid heat sources and direct sunlight. The temperature of the warehouse should be maintained within a certain range, and it must not be too high. At the same time, the air humidity should also be controlled, because it may react with water vapor and cause quality damage, so the storage environment should be ensured to be dry, and desiccant can be placed if necessary. Furthermore, this substance should be stored separately from oxidizing agents, acids, alkalis, etc. Due to its active chemical properties, it is easy to react when in contact with these substances, and may even cause dangerous conditions. The storage area should also be equipped with suitable materials to contain leaks, in case of leakage, it can be dealt with in time.
    As for transportation, it is also necessary to be treated with caution. Make sure that the packaging is intact before transportation, and the packaging materials must have good sealing and corrosion resistance to prevent material leakage. During transportation, the container should be prevented from being hit, vibrated and rubbed to avoid packaging damage. Vehicles should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. Drivers and escorts should be familiar with the properties of the substance and emergency treatment methods. When transporting, you should follow the specified route to avoid densely populated areas and important places to reduce transportation risks. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the surrounding people, isolate the leakage area, and collect and clean up with appropriate materials to avoid greater harm to the environment.
    What is the market price of 4-CHLORO-3-METHYL-PYRIDINE-2-CARBONITRILE?
    4-Chloro-3-methyl-pyridine-2-formonitrile, the price of this product varies from time to time in the market, and also varies with the quality, supply and demand. In the past, the price of chemical substances often depended on a variety of factors. This 4-chloro-3-methyl-pyridine-2-formonitrile, if its quality is high and pure, the preparation is exquisite, and the supply is less and more, the price is high; on the contrary, if the quality is slightly inferior, it is easy to make and more and less, and the price is low.
    Looking at the past market conditions, in the field of fine chemicals, the price of this kind of special reagent is often different according to its use and difficulty in preparation. If used in high-end pharmaceutical synthesis, the purity and impurities are strictly controlled, and the price may be high; if used in general chemical experiments, the quality is slightly delayed, and the price may be slightly reduced.
    However, if you want to determine the price, it is difficult to describe it accurately. Today's chemical market is changing, and the price of raw materials, the innovation of processes, and the guidance of policies all affect its market value. Or consult the chemical industry, or explore the trading platform, to get the current price closer. However, even if you get it, it is only a temporary number, and there may be few changes.