4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

4-Chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is an organic compound. It has a wide range of uses and is mostly used as a key intermediate in the synthesis of specific drugs in the field of medicinal chemistry. Due to the unique structure of this compound, it can introduce special activities to drug molecules, which can effectively enhance the interaction between drugs and targets and improve drug efficacy.
In the process of drug development, chemists can create compounds with novel biological activities by modifying and modifying their structures. For example, in the development of anti-tumor drugs, this compound can be modified to precisely target specific proteins or signaling pathways of tumor cells, inhibiting tumor cell growth and proliferation.
In the field of materials science, it may also have potential uses. Or it can be reasonably designed to participate in the preparation of materials with special photoelectric properties. Because its structure contains nitrogen heterocycles and halogen atoms, it may endow the material with unique electrical and optical properties, such as for the preparation of organic Light Emitting Diodes (OLEDs) or organic solar cell materials, to improve the material's charge transfer efficiency and luminescence properties.
Furthermore, in organic synthetic chemistry, this compound can be used as a key building block to participate in the construction of more complex organic molecular structures. With its halogen atom activity, it can be connected with other organic fragments through various organic reactions, such as coupling reactions, to expand the molecular framework and provide the possibility for the synthesis of organic compounds with diverse structures.

The synthesis method of 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is an important topic in the field of organic synthesis. To obtain this compound, there are various common ways.
First, suitable pyridine derivatives can be used. First, the pyridine ring is modified to introduce specific substituents. For example, pyridine with suitable protective groups is used as the starting material, and chlorine atoms are skillfully introduced through halogenation reaction. For this halogenation reaction, the halogenation reagents and reaction conditions should be carefully selected according to the characteristics of the reaction substrate. Or a specific chlorination reagent can be used to react in a suitable temperature and solvent, so that the chlorine atoms fall precisely at the desired position of the pyridine ring.
Then, the step of introducing iodine atoms is also crucial. The iodine source can be reacted with the precursor compound through metal-catalyzed halogenation reaction, with metal catalysts such as palladium and copper, and corresponding ligands. In this process, the activity of the metal catalyst, the structure of the ligand and the reaction conditions need to be carefully regulated in order to successfully connect the iodine atom to the predetermined position and obtain the structural framework of the target product.
Second, we can also start from the pyrrole derivative. First construct a pyrrole ring, and build a suitable pyrrole structure through a multi-step reaction. Subsequently, through cyclization, the pyrrole is connected to the pyridine fragment to construct the pyrrole [2,3-b] pyridine parent nucleus. In the cyclization process, the reaction mechanism is complex, and attention needs to be paid to the stability and conversion path of the reaction intermediates. Then chlorine and iodine atoms are introduced in sequence. The introduction method can refer to the above halogenation reaction strategy. By precisely controlling the reaction conditions and selecting reagents, the purpose of synthesizing 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine can be achieved.
Synthesis of this compound requires strict control of the reaction conditions, including temperature, pH, reaction time, etc. And the separation and purification after each step of the reaction is also critical. Column chromatography, recrystallization and other means are used to ensure the purity of the intermediate and the final product, so as to successfully synthesize the target compound 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine.

4-Chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine, this is an organic compound. Its physical and chemical properties are quite critical, and it is related to many chemical applications.
Looking at its physical properties, under normal temperature and pressure, this substance may be in a solid state. Many organic compounds with nitrogen-containing heterocyclic structures have such properties. The values of their melting points and boiling points depend on the strength of the intermolecular forces. The presence of chlorine and iodine atoms in the molecule increases the polarity of the molecule, resulting in an increase in the intermolecular forces, so the melting point, boiling point or relatively high.
When it comes to chemical properties, due to the presence of chlorine and iodine atoms in the molecule, the characteristics of the halogen atom are fully revealed. Chlorine and iodine atoms can participate in many nucleophilic substitution reactions. Under suitable reaction conditions, nucleophilic testers can attack the carbon atoms attached to the halogen atoms, causing the halogen atoms to leave and form new compounds. Furthermore, the heterocyclic structure of pyrrolidine imparts a certain alkalinity to the molecule. The lone pair electrons on the nitrogen atom can accept protons, and in an acidic environment, or form quaternary ammonium salts. In addition, the compound may have certain redox activity, and the heterocyclic part may undergo oxidation or reduction reactions under specific conditions, resulting in various chemical transformations.
In conclusion, the physicochemical properties of 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine make it have potential application value in organic synthesis, pharmaceutical chemistry and other fields. It can be used as a key intermediate to construct more complex organic molecular structures.

I look at your question, but I am inquiring about the price range of 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine on the market. However, this is not an easy question to answer, and the price on the market often changes for many reasons.
First, the suppliers are different, and the prices are different. Different merchants may ask for different prices due to different costs, such as the price of purchased raw materials, the complexity of the preparation process, and the amount of operating expenses. Large merchants may have lower costs due to scale effects, and prices may have advantages; small merchants may have higher prices due to various restrictions.
Second, the purchase volume is also the key. Generally speaking, a large quantity is the best price. If you buy a small amount, the merchant may set the price according to the retail price, and the price may be too high; if you buy in bulk, the merchant may lower the price to attract buyers in order to obtain a large order.
Third, the market supply and demand situation has a great impact on the price. If the demand for this product is strong, but the supply is limited, the price may rise; conversely, if the supply exceeds the demand, the merchant will sell it for promotion or reduce the price.
Fourth, the purity of the product also affects the price. For those with high purity, the preparation is difficult, the cost is high, and the price is not cheap; for those with low purity, or because the preparation is easy, the cost is low, and the price is also low.
As far as I know, in the current market, the retail price may be between tens of yuan and hundreds of yuan per gram. If purchasing in bulk, the price per kilogram may be negotiated with the merchant according to the specific quantity, or between several thousand yuan and ten thousand yuan. However, this is only a rough range, and the actual price should be subject to consulting the merchant and considering the real-time market conditions.

4-Chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is a key to the world's research on its safety and toxicity.
As far as is known, this kind of chemical substance has potential applications in many fields due to its special structure, but also its safety and toxicity have attracted much attention. In terms of safety, under normal environmental conditions, without specific excitation factors, it may remain relatively stable and is not prone to spontaneous dangerous reactions. However, once it encounters some active reagents, or is exposed to extreme environments such as high temperature and high pressure, it may cause unpredictable changes. Therefore, when storing and transporting, strict regulations must be followed to ensure environmental and personal safety.
When it comes to toxicity, although there is no very detailed data at present, it is inferred from chemical structural analogies and related analogues that it may have certain toxicity. The presence of halogen atoms may cause them to have special effects in organisms and interfere with normal physiological processes. If it comes into contact with the skin inadvertently, it may cause local irritation, such as redness, swelling, itching, etc.; if inhaled or ingested by mistake, it may involve the respiratory system, digestive system, or even damage the nervous system, resulting in more serious consequences. Therefore, in the development, production and use of 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine, it is necessary to be cautious, operate in strict accordance with safety procedures, and strengthen protective measures to protect people and the environment.