4-Chloro-3-iodo-1H-pyrazolo[4,3-c]pyridine

4-Chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. With its unique chemical structure, pharmaceutical developers can build a variety of bioactive molecules and help create new drugs. For example, in the development of anti-tumor drugs, the structure of the compound can be modified and modified, or substances with high selective inhibitory activity on tumor cells can be obtained.
It also has potential applications in the field of materials science. When some organic semiconductor materials are constructed, it can be used as a structural unit to endow the material with unique electrical and optical properties, such as in the design of organic Light Emitting Diodes (OLEDs) or organic solar cell materials, or to improve device performance.
At the same time, in organic synthetic chemistry, it is an important synthetic building block. Chemists can use various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to build complex organic molecular structures, expand the types and functions of organic compounds, and promote the development of organic synthetic chemistry.

To prepare 4-chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine, there are many common synthesis methods. First, suitable pyridine derivatives can be used to introduce chlorine and iodine atoms through halogenation reaction. First, pyridine is used as a substrate, and chlorine and iodine are introduced at the designated position of the pyridine ring through specific halogenation reagents, such as chlorine-containing and iodine-containing halogenating agents, under suitable reaction conditions, and then the ring-closing reaction is used to construct the structure of pyrazolo [4,3-c] pyridine. In this process, the halogenation reaction conditions are very critical, and precise control of temperature, reaction time and reagent dosage is required to ensure that the halogen atoms are replaced in the expected position.
Second, you can start with pyrazole derivatives. First prepare a pyrazole compound containing a suitable substituent, and then react with a pyridine-containing structural fragment. If the pyrazole is combined with a reagent with a pyridine-related structure and a suitable reaction check point, in the presence of a specific catalyst, through a series of reactions such as condensation and cyclization, the target product is synthesized. The choice of catalyst has a great impact on the reaction process, and different catalysts may cause significant differences in reaction paths and yields.
Furthermore, a step-by-step strategy of building heterocycles can also be adopted. First construct one of the pyrazole rings or the pyridine ring, and then connect the other ring through a suitable reaction and improve the structure. In this process, each step of the reaction needs to be carefully controlled to ensure that the purity of the intermediate product and the reaction direction are accurate, so as to improve the yield and purity of the final product. In short, the synthesis of this compound requires careful selection of suitable synthesis methods based on factors such as the availability of raw materials, the feasibility of reaction conditions and cost considerations.

4-Chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine is an organic compound. To clarify its physical properties, it is necessary to add causo in detail.
It is often in a solid state at room temperature and pressure. Looking at its appearance, it may be in the form of a white to off-white powder. It has such a state because of the characteristics of its molecular structure, which leads to intermolecular interactions.
When it comes to the melting point, the melting point of this compound should be a specific value. However, its exact melting point depends on accurate experimental determination. The atomic arrangement in the cover molecule and the properties of chemical bonds all affect the melting point. Intermolecular forces, such as van der Waals forces, hydrogen bonds, etc., check and balance each other, and jointly determine the melting point.
In terms of solubility, in organic solvents, they may have different behaviors. In common organic solvents such as ethanol and dichloromethane, there may be a certain solubility depending on the interaction between their molecules and solvent molecules. The chlorine, iodine atoms and the heterocyclic structure of pyrazolopyridine affect their affinity with solvent molecules. The solubility of polar solvents and non-polar solvents also varies due to structural differences.
Density is also one of the important physical properties. Although there is no exact value, it can be inferred from its molecular composition and structure. The relative atomic weight of chlorine and iodine atoms in the molecule is relatively large, which increases the overall molecular weight, so its density may be higher than that of ordinary organic compounds.
As for the boiling point, it is affected by the intermolecular force and molecular structure, and it needs to be accurately determined by experiments. The stability of its heterocyclic structure and the existence of halogen atoms are crucial to the effect of the boiling point. If the intermolecular force is strong, the boiling point will increase; otherwise, it will decrease.
The physical properties of this compound are determined by its unique molecular structure, and the properties are interrelated to each other to build a complete picture of its physical properties.

4-Chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine is an organic compound. Its chemical properties are unique and worth exploring.
Let's talk about its physical properties first. Usually, such compounds are mostly solids, and their melting point and boiling point depend on the intermolecular forces, which are closely related to the molecular structure. 4-Chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine molecules contain atoms such as chlorine and iodine. The electronegativity of these atoms will affect the molecular polarity, which in turn will affect the melting point and boiling point.
When it comes to chemical properties, both chlorine and iodine atoms are active check points. Chlorine atoms can participate in nucleophilic substitution reactions because they have a certain tendency to leave. In the presence of appropriate nucleophiles, nucleophilic reagents can attack carbon atoms attached to chlorine and replace chlorine to form new compounds. Similarly, iodine atoms can also participate in similar reactions, but due to the large radius of iodine atoms, their reactivity is different from that of chlorine atoms in some cases.
Furthermore, the pyrazolopyridine structure in this compound gives it a unique electron cloud distribution. The nitrogen atom in this structure has lone pairs of electrons, which can bind to protons and exhibit a certain alkalinity. At the same time, the existence of the conjugated system makes the molecule relatively stable, but it also makes it possible to undergo electron transfer reactions under specific conditions and participate in some redox processes.
In the field of organic synthesis, 4-chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine can be used as an important intermediate. Through further reaction modification of chlorine and iodine atoms, more complex and diverse organic molecular structures can be constructed, providing key synthetic building blocks for pharmaceutical chemistry, materials science and other fields.

I don't know the price range of 4-chloro-3-iodine-1H-pyrazolo [4,3-c] pyridine on the market. This compound may be a special organic synthesis intermediate, and its price is determined by many factors.
First, the difficulty of preparation has a great impact. If the synthesis requires cumbersome steps, expensive reagents or harsh reaction conditions, the cost will be high, and the price will also rise. For example, it requires multiple steps of reaction, and the yield of each step is limited, the raw material loss is large, and the preparation cost will naturally increase.
Second, the amount of market demand is also critical. If there is a strong demand for it in a certain field, such as pharmaceutical research and development, it is a key intermediate, and a large number of pharmaceutical companies are looking for it, the supply is in short supply, and the price will rise. On the contrary, the demand is scarce, and the price may be relatively low.
Third, the production scale plays a role. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price may be more affordable. Small-scale production is difficult to reduce the cost and easy to increase the price.
Fourth, the purity requirements have a significant impact. High-purity products are more difficult to prepare, require complex purification processes, increase the cost, and the price is also high. If used in high-end pharmaceutical research, the purity requirements are almost stringent, and the price must far exceed that of ordinary purity products.
For the exact price range, you can consult chemical raw material suppliers, relevant chemical trading platforms, or professional chemical product price reports. However, due to changes in market dynamics, prices can also change at any time.