4-Chloro-1H-pyrazolo[3,4-b]pyridine

4-Chloro-1H-pyrazolo [3,4-b] pyridine is a kind of organic compound. Its physical properties are quite unique, let me describe them in detail for you.
First of all, its appearance is often white to light yellow crystalline powder. Looking at it, the texture is delicate, like the first snow in winter, and it may have a slight luster under light, like a treasure that hides light.
Second, its melting point is about a specific temperature range. This temperature range is the key node for the substance to change from solid to liquid. The determination of the melting point is like drawing a precise scale for the characteristics of the substance, which can help researchers clarify its purity and characteristics. Near this temperature, the force between the molecules of 4-chloro-1H-pyrazolo [3,4-b] pyridine changes, and the lattice structure gradually disintegrates, resulting in a liquid state.
Furthermore, solubility is also one of its important physical properties. In common organic solvents, its solubility varies. In some organic solvents such as ethanol and dichloromethane, it may exhibit good solubility, just like fish get water, and the molecules are uniformly dispersed in it. However, in water, its solubility may be poor. Due to the characteristics of molecular structure, the interaction with water molecules is weak, making it difficult to form a uniform and stable dispersion system.
In addition, the density of 4-chloro-1H-pyrazolo [3,4-b] pyridine also has a certain value. In density, the mass per unit volume of a substance is also. This value reflects the tightness of its molecular arrangement and is an important indicator of its physical properties.
Its stability is also worthy of attention. Under normal environmental conditions, if properly stored, its chemical structure can be maintained relatively stable. When exposed to high temperature, strong light or specific chemical reagents, chemical reactions may occur, causing changes in its structure and properties.
Overall, the physical properties of 4-chloro-1H-pyrazolo [3,4-b] pyridine, such as appearance, melting point, solubility, density, and stability, are all key elements in the understanding and study of this substance, like a key to unlocking its mysteries.

4-Chloro-1H-pyrazolo [3,4-b] pyridine is one of the organic compounds. Its chemical properties are of great interest and are related to many chemical reactions and characteristics.
First of all, its physical properties, this substance is at room temperature, or in a solid state, and its melting and boiling point is determined by factors such as intermolecular forces. In the molecular structure, the chlorine atom is connected to the structure of pyrazolo-pyridine, resulting in its unique chemical activity.
In terms of reactivity, the chlorine atom is active and can participate in nucleophilic substitution reactions. The cover chlorine atom has an electron-absorbing effect, which makes the electron cloud density on the pyridine ring uneven, making the specific position of the pyridine ring more vulnerable to attack by nucleophilic reagents. For example, by interacting with nucleophiles such as alkoxides and amines, chlorine atoms can be replaced to derive a series of derivatives containing different substituents.
Furthermore, its pyrazolopyridine structure is rich in nitrogen atoms, which have lone pairs of electrons and are basic, which can react with acids to form salts. This property is of great significance in the field of medicinal chemistry, because it can improve the water solubility of compounds by means of salts, which is beneficial to the transport and absorption of drugs in the body.
In addition, due to the existence of a conjugated system, the compound may exhibit certain optical properties and electron transition behavior. In the field of photochemistry and materials science, it may be used to prepare materials with special optical properties. Due to its stable structure and unique electronic properties, it may play an important role in organic synthesis chemistry as a key intermediate for the construction of more complex organic molecules.

4-Chloro-1H-pyrazolo [3,4-b] pyridine has a wide range of uses and shines brightly in the field of pharmaceutical research and development. It can be used as a key intermediate to help create novel drugs. The structure of geinpyrazolo-pyridine has unique biological activities and can specifically bind to many targets in organisms. For example, it can precisely inhibit the activity of certain kinases, which is of great significance in the development of cancer therapeutic drugs. The proliferation and metastasis of cancer cells often depend on the abnormal activation of kinases. Drugs based on this substance are expected to block cancer cell-related signaling pathways and inhibit tumor growth.
In the field of pesticides, it also has its own uses. Efficient insecticides and fungicides can be derived. Due to its specific mechanism of action on pests and pathogens, it can effectively kill or inhibit them, and compared with traditional pesticides, it may have higher selectivity, be environmentally friendly, and have less impact on non-target organisms. It is suitable for the development of green agriculture.
In the field of materials science, 4-chloro-1H-pyrazolo [3,4-b] pyridine has also emerged. Its structural characteristics can be used to synthesize materials with special photoelectric properties. For example, it can be applied to organic Light Emitting Diode (OLED), or it can improve the performance of materials such as luminous efficiency and stability, which adds to the progress of display technology.
In summary, 4-chloro-1H-pyrazolo [3,4-b] pyridine has important application value and broad prospects in the fields of medicine, pesticides and materials science, providing a key boost for innovation and development in many fields.

The synthesis method of 4-chloro-1H-pyrazolo [3,4-b] pyridine has always been studied by chemists. In the past, many wise men have contributed a lot to this topic. Today, we will describe several common methods.
First, using pyridine derivatives as the starting material, after halogenation, cyclization and other steps, this compound can be caused. At the time of halogenation, an appropriate halogenation reagent needs to be selected, and according to the reaction conditions and substrate characteristics, the chlorine atom can precisely replace the hydrogen atom at a specific position on the pyridine ring. Following the cyclization step, by ingeniously designing the reaction system, introducing the nitrogen-containing heterocyclic building group, and under the action of suitable temperature and catalyst, promoting its cyclization, and finally obtaining the target product.
Second, pyrazole derivatives are also used as the starting point. First, the pyrazole ring is modified and a suitable substituent is introduced to pave the way for the subsequent construction of the pyridine ring. After condensation and closed-loop reactions, the pyridine ring is merged with the pyrazole ring. In this process, it is crucial to control the condensation reaction conditions, such as the ratio of reactants, the reaction solvent, and the type and dosage of bases, all of which affect the success or failure of the reaction and the yield.
Furthermore, the method of catalysis by transition metals is also a good way to synthesize this compound. Transition metals such as palladium and copper can effectively catalyze the formation of carbon-nitrogen bonds and carbon-carbon bonds. The construction of the pyrazole-pyridine ring system is achieved by the catalytic coupling reaction of halogenated pyrazole and pyridine substrates in the presence of transition metal catalysts and ligands. The conditions of this method are relatively mild and the selectivity is quite high, but the cost of the catalyst may be a consideration factor.
Each of these synthesis methods has its own advantages and disadvantages. In actual operation, the chemists should weigh the choices according to their own needs, the availability of raw materials and the convenience of reaction conditions, in order to achieve the delicacy of the synthesis.

I have not heard that 4 - Chloro - 1H - pyrazolo [3,4 - b] pyridine is priced on the market. This is a fine chemical, and its price range often varies due to purity, supply and demand, and production costs.
If its purity is high, the preparation method is difficult, and exquisite craftsmanship and rare raw materials are required, the price will be high. However, if the process is gradually ripe, the raw materials are easy to produce, and the mass production is quite abundant, the price may be reduced.
And market supply and demand are also the main reasons. If there are many applicants, and there are few suppliers, the price will rise; conversely, if the supply exceeds the demand, the price may decrease.
Different suppliers have different pricing due to their own cost considerations. There may be those who compete at a good price, or those who win by quality and set a higher price.
Therefore, in order to determine the price range on the market, it is necessary to consider various factors in detail, consult suppliers, and observe the dynamics of the market. Although I cannot directly state the price range, you can follow this idea and explore the chemical raw material market in detail to obtain the approximate price.