4-bromo-7-methoxy-1-tosyl-1H-pyrrolo[2,3-c]pyridine

4-Bromo-7-methoxy-1-tosyl-1H-pyrrolo [2,3-c] pyridine is also an organic compound. Its chemical structure is quite complex, and it is composed of a variety of atoms and functional groups.
Looking at its name, "4-bromo" indicates that there is a bromine (Br) atom substitution at a specific position (position 4). Bromine atoms, atoms of halogen elements, also have certain chemical activity, and can often cause various changes in organic reactions, or participate in nucleophilic substitution, or involve free radical reactions.
"7-methoxy" indicates the presence of a methoxy group (-OCH 🥰) at position 7. Methoxy is the electron cloud distribution of the molecule, which can affect the physical and chemical properties of the compound, such as affecting its polarity, stability and reactivity.
"1-tosyl" refers to the presence of a p-toluenesulfonyl group (-SO ² C H CH) at position 1. This functional group is large in size and has unique electronic effects, which has a significant impact on the spatial structure and chemical behavior of the molecule. It can often enhance the stability of molecules, and at the same time, it can be used as a good leaving group in some reactions to promote the reaction process.
And "1H-pyrrolo [2,3-c] pyridine" outlines the core skeleton of this compound, which is composed of pyrrolido-pyridine structure. Both pyrrole and pyridine are nitrogen-containing heterocycles, which are combined to form a unique conjugate system, which endows the molecule with special electronic properties and biological activities. The conjugate system makes the molecule have a certain aromaticity, which affects its chemical reaction selectivity and spectral properties.
In summary, the chemical structure of 4-bromo-7-methoxy-1-tosyl-1H-pyrrolo [2,3-c] pyridine is composed of bromine atom, methoxy group, p-toluenesulfonyl group and pyrrolido-pyridine skeleton. Each part interacts to jointly determine the unique properties and reactivity of this compound.

4-Bromo-7-methoxy-1-tosyl-1H-pyrrolo [2,3-c] pyridine is an organic compound. Its main use is quite important in the field of organic synthesis.
First, it is often used as a key intermediate to prepare complex heterocyclic compounds. Due to its unique molecular structure, it can be derived from a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to provide a basis for the creation of novel compounds in the fields of medicinal chemistry and materials science. For example, in drug development, this compound can be modified to construct molecules with potential biological activity and explore its effect on specific disease targets.
Second, it also has potential value in material synthesis. Because it has certain electronic properties and structural stability, it may participate in the construction of organic semiconductor materials. Through rational design and synthesis, the electrical and optical properties of the material can be adjusted, which is expected to be applied to the fields of organic Light Emitting Diodes (OLEDs), organic solar cells and other optoelectronic devices to improve the performance and efficiency of the device.
Third, in chemical biology research, it can be used as a probe molecule. By appropriately modifying it, specific fluorophores or biological activity tags are introduced to track chemical reactions in organisms and monitor the interactions of biomolecules. In this way, researchers can gain in-depth insight into the complex physiological processes and molecular mechanisms in organisms.
In short, 4-bromo-7-methoxy-1-tosyl-1H-pyrrolo [2,3-c] pyridine has shown broad application prospects in various fields such as organic synthesis, materials science, and chemical biology, providing many possibilities for scientific research and technological innovation.

To prepare 4-bromo-7-methoxy-1-p-toluenesulfonyl-1H-pyrrolido [2,3-c] pyridine, the method is as follows:
Starting material, often take a compound containing pyrrolido-pyridine parent nucleus, which has a partial check point or a modifiable group in its structure for subsequent introduction of the target substituent. For example, select a pyrrolido-pyridine derivative with a suitable protective group or an active check point, which is the basic raw material for the reaction.
First, a methoxy group is introduced. The nucleophilic substitution reaction is often carried out with the corresponding phenolic compounds and halomethane in an alkaline environment and in the presence of a phase transfer catalyst. Bases such as potassium carbonate, in suitable organic solvents (such as N, N-dimethylformamide), phenolic hydroxyl negative ions nucleophilically attack the carbon atoms of halomethane, and the halogen ions leave to obtain methoxy substitution products. This step requires temperature control and time control to ensure that the reaction is sufficient and there are few side reactions.
Second, bromine atoms are introduced. Depending on the activity of the substrate, different brominating reagents can be selected. If the substrate activity is high, bromine can be selectively brominated in a suitable solvent (such as dichloromethane) under the catalysis of Lewis acid. If the activity is low, N-bromosuccinimide (NBS) is often preferred. In the presence of light or a radical initiator, NBS produces bromine radicals to achieve bromination of the target check point to obtain pyrrolido-pyridine intermediates containing bromine and methoxy groups.
Finally, access 1-p-toluenesulfonyl group. Using p-toluenesulfonyl chloride as a reagent, under basic conditions, react with the aforementioned intermediates. The base (such as triethylamine) captures the hydrogen on the nitrogen atom of the intermediate to form a nitrogen anion. Its nucleophilic attack on the sulfur atom of p-toluenesulfonyl chloride, and the chloride ion leaves to obtain 4-bromo-7-methoxy-1-p-toluenesulfonyl-1H-pyrrolido [2,3-c] pyridine target product. After the reaction is completed, the pure product can be obtained by extraction, column chromatography and other methods.

4-Bromo-7-methoxy-1-p-toluenesulfonyl-1H-pyrrolido [2,3-c] pyridine, which is an organic compound. Its physical properties are as follows:
Viewed at room temperature and pressure, or solid, because this class of organic compounds containing heterocycles and many substituents is mostly solid. Its color may vary from colorless to light yellow, because although there is no significant chromophore in the molecular structure, the substituents and conjugated systems may cause weak color.
Smell it, or have a special organic odor. However, the exact odor is difficult to describe precisely due to the complexity of the molecular structure, and the odor of organic compounds is often related to its volatility. Its volatility is relatively low, and the odor emission is weak.
When it comes to the melting point, although there is no accurate data, it is speculated that the melting point is high due to the interaction of hydrogen bonds and van der Waals forces between molecules. Bromine atoms, methoxy groups, p-toluenesulfonyl groups and other substituents in the molecule increase the intermolecular force, resulting in the need for higher energy to overcome the force and turn the solid state into a liquid state, so the melting point is high.
In terms of solubility, considering that it is an organic compound and contains hydrophobic groups such as benzene ring and pyridine ring in the molecule, the solubility in water is very In common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), there may be a certain solubility. Because these organic solvents and the compound molecules can form similar miscibility, such as dichloromethane and the compound molecules can interact through van der Waals force, polar organic solvents such as DMF and DMSO form hydrogen bonds or dipole-dipole interactions with polar groups in the compound, which is conducive to dissolution.
The density is slightly larger than that of water. Because its molecular structure contains bromine atoms, the relative atomic weight of bromine atoms is larger, which increases the molecular weight. And the molecular structure is compact, which increases the unit volume mass, so the density is greater than that of water. The above physical properties are based on the molecular structure of the compound, and the exact properties need to be determined experimentally.

4-Bromo-7-methoxy-1-tosyl-1H-pyrrolo [2,3-c] pyridine is an organic compound. Looking at its market prospects, it can be viewed from multiple perspectives.
In the field of pharmaceutical research and development, organic heterocyclic compounds are often the key building blocks for the creation of new drugs. The unique structure of this compound may hold the potential for affinity and activity in specific disease targets. If there is an urgent demand for new anti-cancer and antiviral drugs, compounds containing such structures may emerge in the process of drug screening and optimization, and achieve the purpose of treating diseases by regulating specific biological pathways. Therefore, in the field of medicine, its market prospects may expand with the progress of new drug research and development.
In the field of materials science, the development of organic optoelectronic materials is in the ascendant. Organic compounds with specific electronic structures and optical properties are expected to be the cornerstones for the preparation of high-performance Light Emitting Diodes, solar cells and other materials. If properly modified and formulated, this compound may exhibit unique photoelectric properties, such as fluorescence emission at specific wavelengths and efficient charge transport capabilities, etc., thus gaining a place in the market of new optoelectronic materials.
However, its market expansion is not smooth. The complexity and high cost of the synthesis process may hinder its large-scale application. To enhance market competitiveness, chemists need to innovate in synthesis methods, find simple, efficient, green and economical synthesis paths, and reduce their production costs. And the market's acceptance of new materials and new drugs often depends on strict regulatory approval and long clinical validation. Therefore, in order to develop the market prospect of this compound, it is necessary for scientific research, production and regulatory parties to work together to shine in the fields of medicine and materials and find a broad market space.