4-bromo-6-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

4-Bromo-6-methoxypyrazolo [1,5-a] pyridine-3-carbonitrile is an organic compound with interesting and complex chemical properties. This compound contains functional groups such as bromo, methoxy, pyrazolo [1,5-a] pyridine and carbonitrile, each of which endows it with unique chemical behaviors.
Nitrile groups have high reactivity and can participate in many reactions, such as hydrolysis to form carboxylic acids or amides under appropriate conditions. Methoxy groups are the power supply groups, which can affect the distribution of molecular electron clouds, increase the density of aryl electron clouds, and enhance their electrophilic substitution reactivity. Bromine atoms are not only potential leaving groups, which can be replaced by other nucleophilic reagents in nucleophilic substitution reactions, but also affect molecular physical properties.
Its chemical properties are also restricted by the overall structure of the molecule. The pyrazopyridine skeleton imparts specific spatial configuration and electronic properties to the molecule, which affects the interaction and reactivity of each functional group. In organic synthesis, derivatives with more complex structures can be modified and transformed by using the characteristics of each functional group under appropriate reaction conditions to meet the needs of pharmaceutical chemistry, materials science and other fields. For example, changing the bromine atom linking group through nucleophilic substitution reaction or chemically modifying the nitrile group can expand the application range of this compound.
The chemical properties of this compound are determined by its functional group and molecular structure, which is of great significance in organic chemistry research and related application fields, and lays the foundation for further exploration and development of new compounds.

The common synthesis methods of 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-formonitrile are as follows:
Select a suitable pyridine derivative from the starting material. Under specific reaction conditions, the methoxy group is first introduced into the derivative. The commonly used method is to heat and stir the reaction in a suitable solvent such as N, N-dimethylformamide (DMF) with the corresponding halogenated pyridine and sodium methoxide alkoxylation reagents. In this process, the halogen atom is replaced by a methoxy group to form a methoxy-containing pyridine intermediate.
Then, the pyrazole ring structure is introduced into the intermediate. Nitrogen-containing heterocyclic construction reagents, such as appropriate hydrazines and aldoxides or ketones, are often catalyzed by acids or bases, through a series of reactions such as condensation and cyclization to form a pyrazolopyridine skeleton.
As for the introduction of bromine atoms, it is mostly carried out after the construction of the pyrazolopyridine structure. Brominating reagents, such as N-bromosuccinimide (NBS), can be selected. In the presence of initiators such as benzoyl peroxide (BPO), in inert solvents such as carbon tetrachloride, under light or heating conditions, the substitution of bromine atoms at the target position can be achieved.
The introduction of cyano groups is often reacted with cyanide reagents by halogenates. For example, when the bromine-containing intermediate is reacted with cyanide reagents such as cuprous cyanide under specific organic solvent and temperature and pressure conditions, the halogen atom is replaced by cyanyl group, and the final product is 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-formonitrile. Each step of the reaction requires fine control of the reaction conditions, including temperature, reaction time, material ratio, etc., and the product needs to be separated and purified to achieve the required purity.

4-Bromo-6-methoxypyrazolo [1,5-a] pyridine-3-formonitrile is an organic compound. In today's world, its application field is quite extensive.
First, in the field of pharmaceutical chemistry, such compounds containing nitrogen heterocyclic structures often have unique biological activities. Many studies have focused on exploring its potential medicinal value, or it can be used as a lead compound, and new drugs can be developed through structural modification and optimization. For specific disease-related targets, derivatives of 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-formonitrile may exhibit good inhibitory or regulatory effects, providing the possibility for the creation of new drugs.
Second, in the field of materials science, organic compounds have attracted attention due to their unique photoelectric properties. The special structure of 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-formonitrile may give it certain optoelectronic properties, which can be used to prepare organic optoelectronic materials, such as organic Light Emitting Diodes, solar cells and other devices, to help improve material properties and device efficiency.
Furthermore, in the field of organic synthesis chemistry, it plays an important role as a key intermediate. With its specific functional groups, it can connect and transform with other organic molecules through various chemical reactions to construct more complex and diverse organic compound structures, providing an important cornerstone and path for the development of organic synthesis chemistry.

What you are asking about is the market price of 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-carbonitrile. However, the market price of this chemical is difficult to say in a single word. The price is influenced by many factors.
The first to bear the brunt is the difficulty of its preparation. If the preparation method is complicated, the required raw materials are rare or the preparation process is lengthy, and it consumes a lot of manpower and material resources, the price will be high. The unique structure of this compound, or the need for special reaction conditions and reagents, can cause the cost to rise, which in turn affects its market price.
Furthermore, the balance between market supply and demand is also key. If the demand for this product is strong in the fields of pharmaceutical research and development, chemical production, etc., but the supply is limited, the so-called "rare is expensive", its price will rise. On the contrary, if there is little demand and excess production, the price will inevitably fall.
There are different manufacturers, which will also make the price different. Large factories may reduce costs and prices may be competitive due to scale effects; while small factories may have higher prices due to their small production scale and lower cost control than large factories.
And market conditions are changing rapidly, fluctuations in raw material prices, and the impact of policies and regulations can make the price of this chemical fluctuate.
Therefore, if you want to know the exact market price of 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-carbonitrile, you can get more accurate price information when you pay attention to the chemical product trading platform in real time, consult relevant suppliers or industry insiders.

4-Bromo-6-methoxypyrazolo [1,5-a] pyridine-3-carbonitrile is an organic compound. The storage conditions of such compounds are crucial to their stability and quality.
It should be stored in a cool, dry and well-ventilated place. A cool place can prevent the molecular movement of the compound from intensifying due to excessive temperature, triggering chemical reactions and causing it to deteriorate. Excessive temperature may break chemical bonds and change its chemical structure.
A dry place is also indispensable. Water vapor in the air may react with the compound, such as hydrolysis, which affects its purity and properties. Water vapor may destroy intermolecular forces and change crystal structure.
Well ventilated can disperse the volatile and harmful gases that may be generated in time, avoid potential safety hazards caused by accumulation, and help to maintain the stability of the storage environment.
In addition, it should be stored separately from oxidants, acids, bases and other substances. Due to its chemical properties, or react violently with the above substances. Oxidants have strong oxidizing properties, or cause the compound to be oxidized; changes in the acid-base environment may also cause chemical changes and destroy the molecular structure.
During storage, attention should also be paid to avoid light. Some organic compounds are sensitive to light, and chemical reactions under light or lead to luminescence affect their quality and performance.
In conclusion, 4-bromo-6-methoxypyrazolo [1,5-a] pyridine-3-carbonitrile storage requires careful maintenance of a cool, dry, ventilated environment, isolation from incompatible substances, and avoidance of light to ensure its quality and stability.