4-bromo-3-cyanopyridine

4-Bromo-3-cyanopyridine is also an organic compound. It has a wide range of uses and is often a key intermediate in the creation of drugs in the field of medicinal chemistry. Due to its special chemical structure, it can react with many reagents and derive biologically active substances for the treatment of various diseases.
In materials science, it also has its uses. It can participate in the synthesis of functional materials with specific properties, such as those with special optoelectronic properties, used in optical devices, electronic components, etc., to help its performance gain.
In pesticide chemistry, it is also indispensable. With this as raw material, pesticides with high insecticidal, bactericidal or herbicidal properties can be prepared to protect agricultural production and increase its yield and quality.
And because of its unique structure, in the study of organic synthetic chemistry, it is often an important substrate for chemists to explore new reaction paths and expand synthesis methods. It has made great contributions to the progress of organic synthetic chemistry.

There are various ways to synthesize 4-bromo-3-cyanopyridine. First, it can be prepared from 3-cyanopyridine by bromination reaction. In this method, a suitable brominating agent, such as liquid bromine or N-bromosuccinimide (NBS), is often used under suitable reaction conditions. If liquid bromine is used, it is necessary to heat or light in the presence of a catalyst, such as iron powder or iron tribromide, to promote the reaction. This reaction mechanism involves the electrophilic substitution of bromine positive ions at specific positions on the pyridine ring, and 3-cyano groups are used as meta-locators to guide bromine atoms into the 4-position to obtain the target product. < Br >
Second, it can be constructed from suitable pyridine derivatives through multi-step reactions. For example, pyridine containing suitable substituents is prepared first, and then cyanyl is introduced and brominated. If the starting material contains groups that can be converted into cyanyl groups, such as halogen atoms, cyanide can be introduced by reacting with cyanide reagents, such as potassium cyanide and sodium cyanide, in suitable solvents and catalysts, and then brominated to obtain 4-bromo-3-cyanopyridine.
Third, it is synthesized by metal-catalyzed coupling reaction. Bromopyridine derivatives and cyanide-containing reagents are selected to realize the coupling of carbon-bromo bonds and carbon-cyano bonds under the action of metal catalysts such as palladium catalysts. Such methods require specific reaction conditions, such as suitable ligands, bases and solvents, to promote the efficient reaction and obtain higher yields of 4-bromo-3-cyanopyridine.

4-Bromo-3-cyanopyridine is one of the organic compounds. It has specific physical properties, so let me tell you one by one.
Looking at its appearance, under room temperature and pressure, 4-bromo-3-cyanopyridine is mostly white to light yellow crystalline powder. This form is easy to store and transport, and in many chemical reactions, because it is a solid state, it can precisely control the dosage, so that the reaction can be carried out in an orderly manner.
As for the melting point, the melting point of this compound is quite important, about 126-129 ° C. The characteristics of the melting point, like the "personalized label" of a compound, can not only help to distinguish its purity, but also serve as a key reference index in the synthesis and purification process. When the substance is heated to the melting point range, it gradually melts from a solid state to a liquid state. This transformation process requires a specific amount of heat to reflect the strength of its intermolecular forces.
In terms of solubility, 4-bromo-3-cyanopyridine exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), etc. This property is of great significance in the operation of organic synthesis, because it can be uniformly dispersed with the help of suitable organic solvents, so as to promote full contact with other reactants and accelerate the reaction process. However, its poor solubility in water is also in line with the generality of many organic compounds. Due to the ratio of polar groups to non-polar parts in its molecular structure, it is difficult to dissolve in water with strong polarity.
In addition, the stability of this compound also needs attention. Under normal storage conditions, if stored in a cool and dry place protected from light, 4-bromo-3-cyanopyridine can remain relatively stable. However, when it encounters strong oxidizing agents, strong acids, strong bases and other chemicals, it may cause chemical reactions and cause its structure to change.
In summary, the physical properties of 4-bromo-3-cyanopyridine, such as appearance, melting point, solubility and stability, are indispensable factors in many fields such as organic synthesis and drug development, and play a decisive role in its subsequent application.

4-Bromo-3-cyanopyridine, an important compound in organic chemistry, is widely used in pharmaceuticals, materials science and other fields. As for its market price, it is difficult to say a word, because many factors affect it.
The first to bear the brunt, the market supply and demand relationship is the key factor. If the market demand for 4-bromo-3-cyanopyridine is strong, but the supply is relatively scarce, the price will rise; conversely, if the supply exceeds the demand, the price will easily decline. If the pharmaceutical industry has developed rapidly in recent years, the demand for this compound has increased greatly, and if the production and supply fail to keep up in time, the price will rise.
In addition, the production cost also affects its price. To produce 4-bromo-3-cyanopyridine, the procurement of raw materials, reaction processes, and equipment maintenance all require costs. Raw material price fluctuations directly affect the total cost. If raw materials are scarce or difficult to produce, the price will be high, which will in turn cause the price of 4-bromo-3-cyanopyridine to rise. Although new process research and development may reduce costs, initial R & D investment will also affect prices in the short term.
In addition, differences between manufacturers and brands also have an effect on prices. Production by well-known large factories, due to strict quality control and good reputation, product prices may be relatively high; products from small factories may be slightly lower due to cost control, but the quality may vary.
The market competition situation cannot be ignored either. When the competition is fierce, manufacturers may adjust their price strategies, reduce prices, or launch preferential activities in order to compete for share.
From this perspective, the market price of 4-bromo-3-cyanopyridine is changing dynamically. If you need the exact price, you can consult chemical product suppliers, distributors, or professional chemical product trading platforms to get the latest price information.

4-Bromo-3-cyanopyridine is also an organic compound. When storing and transporting, pay attention to many matters.
First word storage. This compound should be stored in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, if it is placed in a warm and humid place, it may cause deterioration and damage its quality. Keep away from fires and heat sources to prevent fires. And should be stored separately from oxidizing agents, acids, bases, etc., because of contact with them, or violent chemical reactions, causing danger. At the same time, the storage place should be prepared with suitable materials to contain leaks, just in case.
Times and transportation. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. Transportation vehicles should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to avoid high temperature periods, due to high temperature or increase its danger. During transportation, it should be protected from exposure to the sun, rain and high temperature. Road transportation should follow the prescribed route and do not stop in residential areas and densely populated areas. Railway transportation should also abide by relevant regulations, properly packaged and fixed to ensure transportation safety. In short, the storage and transportation of 4-bromo-3-cyanopyridine must be handled with caution and strictly abide by various rules to ensure safety.