4 Bromo 2 3 Dimethylpyridine 1 Oxide
pyridine pyrrole pyrazine piperidine piperazine

4-bromo-2,3-dimethylpyridine 1-oxide

    Specifications

    HS Code

    118271

    Chemical Formula C7H10BrNO
    Molecular Weight 202.07
    Appearance Solid (usually)
    Physical State At Room Temperature Solid
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Limited solubility likely
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
    Density Data needed
    Flash Point Data needed
    Pka Value Data needed
    Vapor Pressure Data needed

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    General Information
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    Frequently Asked Questions

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    What are the chemical properties of 4-bromo-2,3-dimethylpyridine 1-oxide?
    4-Bromo-2,3-dimethylpentane-1-oxide, this is an organic compound with specific chemical properties. Its molecules contain bromine atoms, methyl and oxide functional groups, which give it unique reactivity.
    In nucleophilic substitution reactions, the bromine atom has a certain electronegativity, which makes the C-Br bond polar and vulnerable to attack by nucleophiles. Nucleophiles can replace bromine atoms to form new organic compounds. For example, when co-heated with aqueous sodium hydroxide, hydroxyl (-OH) will replace bromine atoms to form 4-hydroxy-2,3-dimethylpentane-1-oxide.
    In a redox reaction, the oxide part can participate in the reaction. In case of a strong oxidizing agent, the oxide part may be further oxidized, changing the oxidation state of the oxygen atoms in the molecule, resulting in changes in the structure and properties of the compound. Conversely, in case of a reducing agent, the oxide may be reduced, and the binding mode of the oxygen atoms changes to form different products.
    In addition, the hydrocarbyl part of the compound will also participate in the reaction. Due to the electron cloud effect of alkyl groups such as methyl groups, it will affect the electron cloud density of the carbon atoms connected to it, which in turn affects the reactivity of the entire molecule. For example, when reacting with certain reagents, the hydrocarbyl part may undergo reactions such as substitution and addition, depending on the reaction conditions and the reagents
    What are the preparation methods of 4-bromo-2,3-dimethylpyridine 1-oxide?
    To prepare 4-bromo-2,3-dimethylpyridine-1-oxide, the following methods can be used:
    First, start with 4-bromo-2,3-dimethylpyridine, select a suitable oxidizing agent, such as m-chloroperoxybenzoic acid (m-CPBA), in a suitable solvent, such as dichloromethane, control low temperature, such as 0 ° C to room temperature, so that it can slowly react. In this process, the oxygen atom of the oxidizing agent is gradually added to the pyridine nitrogen atom to form 4-bromo-2,3-dimethylpyridine-1-oxide. After the reaction is completed, the product is purified by extraction, column chromatography, etc. The reaction mechanism is that the oxygen atom of peroxy acid is electrophilic, attacking the lone pair of electrons of the pyridine nitrogen atom to form N-oxide.
    Second, 2,3-dimethylpyridine can be oxidized first to obtain 2,3-dimethylpyridine-1-oxide, and then reacted with brominating reagents, such as N-bromosuccinimide (NBS), in the presence of light or initiators, in suitable solvents, such as carbon tetrachloride. Because the nitrogen atom of pyridine-1-oxide is positively charged, the electron cloud density of the pyridine ring changes, and the bromination reaction is selected to the 4-position. After the reaction, the target product can be obtained by regular separation and purification. The light or initiator acts on NBS to produce bromine free radicals and initiate bromination reaction.
    Third, a suitable halogenated pyridine derivative is used as the raw material, and the position of the halogen atom is converted into a bromine atom under appropriate reaction conditions. At the same time, methyl is introduced at the 2,3-position of the pyridine ring, and the nitrogen oxide atom forms an oxide. However, this approach is a little complicated, and the reaction conditions of each step need to be precisely controlled to ensure the purity and yield of the product. Each method has its own advantages and disadvantages. The most suitable method should be selected according to the actual situation, such as the availability of raw materials, cost, and product purity requirements.
    What fields are 4-bromo-2,3-dimethylpyridine 1-oxide used in?
    4-Bromo-2,3-dimethylpyridine-1-oxide is useful in various fields.
    In the field of pharmaceutical research and development, it is often an important intermediate. With its unique chemical structure, it can participate in various reactions and help build complex drug molecular structures. Taking the synthesis of specific targeted drugs as an example, through its ingenious reaction with other reagents, it can precisely introduce key functional groups, paving the way for the development of new drugs with high efficiency and low toxicity.
    It can also be seen in the field of materials science. Because of its specific electronic properties and spatial structure, it can be used to prepare functional materials. For example, the preparation of organic materials with special optical or electrical properties can contribute to the development of new display technologies, sensors and other fields. It may be able to adjust the energy level structure of the material, improve the charge transport performance of the material, and then enhance the functionality of the material as a whole.
    In the field of organic synthetic chemistry, this compound is like a delicate key, opening the door to many novel reactions. Chemists can use its activity check point to carry out unique chemical reactions and synthesize a series of organic compounds with novel structures and potential application value. For example, through ingenious design of reaction routes, it can react with different nucleophiles or electrophiles, expand the structural diversity of organic compounds, and inject new vitality into the development of organic synthetic chemistry. From this perspective, 4-bromo-2,3-dimethylpyridine-1-oxide plays an important role in many fields such as medicine, materials, and organic synthesis, and has made a lot of contributions to the progress of various fields.
    What is the market outlook for 4-bromo-2,3-dimethylpyridine 1-oxide?
    #4-Bromo-2,3-dimethylpyridine-1-oxide market prospect theory
    Guanfu 4-bromo-2,3-dimethylpyridine-1-oxide, which is emerging in the current market, is worth exploring in the future.
    From the perspective of the pharmaceutical field, this compound can be called a key intermediate in pharmaceuticals. Today, the research and development of many new drugs is increasingly in demand. Due to its special chemical structure, it can endow drug molecules with unique activity and stability. Taking the research and development of anti-cancer drugs as an example, many scientific research teams are focusing on this, hoping to use 4-bromo-2,3-dimethylpyridine-1-oxide as the cornerstone to build new anti-cancer drugs with high efficiency and low toxicity. Under this trend, the pharmaceutical industry's procurement volume is increasing day by day, and the market space is also expanding.
    Looking at the field of pesticides, 4-bromo-2,3-dimethylpyridine-1-oxide also has outstanding performance. With the process of agricultural modernization, the demand for efficient and environmentally friendly pesticides is eager. The compound can be used as an important raw material for the synthesis of new pesticides. The pesticides produced by it have the characteristics of high selectivity and low residue, which can not only effectively eliminate pests and diseases, but also fit the current development concept of green agriculture. Therefore, pesticide manufacturers continue to pay more attention to it, injecting strong impetus into the market.
    In the field of materials science, 4-bromo-2,3-dimethylpyridine-1-oxide has also emerged. With the progress of science and technology, the research and development of new functional materials is in the ascendant. This compound may participate in the synthesis of high-performance polymers and electronic materials, giving the materials special electrical and optical properties. Although the application is still in its infancy at this stage, its potential is huge, and it will definitely bring new growth points to the market over time.
    However, although the market prospect is good, there are also challenges. Its synthesis process is complex and the cost remains high, which restricts its large-scale application. And the market competition is becoming increasingly fierce, and many production enterprises are competing for the deer, with uneven quality. To seek long-term development, enterprises must strive to optimize the synthesis process, reduce costs and increase efficiency, and at the same time strictly observe the quality checkpoint in order to stand at the forefront of the market wave.
    To sum up, although 4-bromo-2,3-dimethylpyridine-1-oxide faces challenges, the market prospect is still broad, driven by the demand in the fields of medicine, pesticides, and materials, and the future is promising.
    What are the physical properties of 4-bromo-2,3-dimethylpyridine 1-oxide?
    4-Bromo-2,3-dimethylpentane-1-oxide, this substance is an organic compound. Its physical properties are quite unique, let me tell you in detail.
    Looking at its appearance, under room temperature and pressure, this compound is often in the form of a colorless to light yellow liquid, with a clear texture, like a clear stream. When you get close to it, you can detect that it exudes a special smell, but this smell is not pungent, but it is unique, just like a unique smell hidden in the mountains and forests.
    When it comes to the melting point, due to the characteristics of the molecular structure, the melting point of the substance is low, and it is liquid at room temperature. The boiling point is within a certain range, but the exact value will vary due to changes in external pressure. Generally speaking, under standard atmospheric pressure, its boiling point is sufficient to cause it to undergo a phase transition under common heating conditions, from liquid to gaseous state, like a phoenix nirvana, undergoing a morphological transformation.
    As for density, 4-bromo-2,3-dimethylpentane-1-oxide is slightly lighter than water, like a light feather. If it is placed in one place with water, it will leisurely float on the water surface and form a distinct state.
    Solubility is also one of its important physical properties. This substance exhibits good solubility in organic solvents, such as ethanol, ether, and other common organic solvents, which can be fused with it, just like old friends reunite and are intimate; however, its solubility in water is quite limited, just like the incompatibility of oil and water, the two meet, each is a camp, and it is difficult to integrate.
    In addition, 4-bromo-2,3-dimethylpentane-1-oxide has a certain volatility, and it will slowly evaporate in the air, just like the fragrance of flowers in spring, gradually dissipating into the invisible. Its steam and air can form explosive mixtures, and this property also warns that extra caution is required during use and storage, as if treating a potentially dangerous fire with a little carelessness could lead to disaster.