4-AMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER

4-Hydroxypyridine-3-carboxymethyl ester is a key intermediate in organic synthesis. It has a wide range of uses, especially in the field of medicinal chemistry.
In terms of drug development, this compound can be used as a key starting material to construct molecular structures with specific biological activities. Like some new therapeutic drugs for specific diseases, in the synthesis process, 4-hydroxypyridine-3-carboxymethyl ester can participate in a series of reactions with its unique chemical structure, and then shape complex molecules that meet the needs of drug targets.
For example, when developing anti-tumor drugs, chemists can introduce other active groups by structural modification and derivatization of 4-hydroxypyridine-3-carboxymethyl ester to enhance the targeting and inhibitory effect of the drug on tumor cells.
In the field of materials science, it also shows potential value. Because of its certain reactivity and structural properties, it can be used to prepare some functional polymer materials. Through appropriate polymerization, 4-hydroxypyridine-3-carboxymethyl ester is integrated into the polymer chain to impart special optical, electrical or mechanical properties to the material, so as to meet the requirements of material properties in different application scenarios.
In addition, in the preparation of fine chemical products, 4-hydroxypyridine-3-carboxymethyl ester can be used as an important intermediate for the synthesis of fine chemicals such as fragrances and dyes. After a series of chemical transformations, compounds with unique aroma or color characteristics can be prepared, which are used in industrial processes such as fragrance blending and dye production.
To sum up, 4-hydroxypyridine-3-carboxymethyl ester, with its diverse reactivity and unique structure, occupies an important position in many fields such as medicine, materials, and fine chemicals, and plays an indispensable role in promoting the development of related fields.

Ethyl 4-hydroxybutyric acid-3-acetoacetate is an important compound in organic chemistry. Its physical properties are quite unique, let me tell you in detail.
This substance is mostly a colorless to pale yellow transparent liquid at room temperature, with a clear texture, like a mountain spring. Looking at its appearance, it has a flowing beauty. Under the light, there may be a faint luster flickering, just like a pearl hidden in the dark.
Smell its smell, often with a special fragrance, not a pungent and intolerable smell, but a relatively mild and unique fragrance. Although it is not rich and flamboyant, it can also be captured by the sense of smell. It seems to be nothing, just like the fragrance of wild flowers blooming quietly in the forest.
When it comes to the boiling point, the boiling point of this compound is about a certain range (the specific value needs to be determined by precise experiments). The boiling point is the critical temperature at which a substance changes from liquid to gaseous. When the temperature gradually rises to the boiling point, ethyl 4-hydroxybutyric acid-3-acetoacetate is like a butterfly pupa, breaking free from the shackles of the liquid state and rising into a gaseous state. This property is of great significance in the process of separation and purification. By controlling the temperature, the substance can be separated from other substances with different boiling points, just like clever screening, and each belongs to its place.
As for the melting point, it is also a specific value (the exact value depends on the experiment). When the melting point is reached, the substance changes from a solid state to a liquid state. Below the melting point, ethyl 4-hydroxybutyric acid-3-acetoacetate is like sleeping ice, quietly solidifying; and once the temperature rises to the melting point, it is like ice and snow melting and slowly turns into a liquid state.
In terms of solubility, it has good solubility in organic solvents, such as ethanol, ether, etc. This is like a fish in water, in these organic solvents, it can be evenly dispersed and fused. However, the solubility in water is relatively limited, just like the incompatibility of oil and water, only a small amount can be affinity with water, most of them will still be separated from water and form a layered state. This solubility characteristic plays a key role in guiding the choice of its separation and reaction environment in chemical experiments and industrial production, just like lighting a beacon for the chemical reaction path.

To prepare ethyl 4-hydroxypyridine-3-carboxylate, the method is as follows:
First take an appropriate pyridine derivative as the starting material, which reacts with a reagent containing hydroxyl groups under specific reaction conditions. During the reaction, the temperature should be controlled moderately, and a suitable catalyst should be selected so that the hydroxyl group can precisely replace the atom at a specific position on the pyridine ring to obtain a pyridine intermediate containing hydroxyl groups.
Then, the intermediate and the reagent containing carboxyl ethyl ester are co-placed in the reaction system to adjust the pH of the reaction. By appropriate chemical reactions, the carboxyl ethyl ester is partially connected to the designated place on the pyridine ring, and then 4-hydroxypyridine-3-carboxylic acid ethyl ester is formed.
During the reaction process, the temperature, pH, time and the ratio of each reactant need to be carefully adjusted. If the temperature is too high or too low, the reaction may be biased towards side reactions, or the reaction rate may be too slow. Unsuitable pH will also affect the progress of the reaction and the purity of the product. If the proportion of reactants is inappropriate, it is not only a waste of raw materials, but also difficult to achieve the formation of the desired product.
When operating, it is advisable to follow the specifications of chemical experiments in a well-ventilated environment, and monitor the reaction process in real time by appropriate analytical means to ensure that the reaction proceeds according to the predetermined path, and the purity and yield of the product reach the ideal environment. In this way, ethyl 4-hydroxypyridine-3-carboxylate can be effectively prepared.

4-Hydroxypyridine-3-carboxyethyl ester, in the market, its price range is related to various reasons, and it is difficult to generalize.
If this compound is of ordinary quality, and the supply in the market is abundant, and the demand is not unusual, its price may be relatively flat. However, in the field of chemical industry, the price of raw materials often varies with the origin, season, and current situation, which is also one of the major factors affecting its price. If its raw materials are scarce, or the refining techniques are complicated, the cost will increase, and the price will also rise.
Furthermore, the business's business strategy and logistics costs are also involved in the price. All kinds of merchants, in order to compete for market share or offer preferential policies, the price may fluctuate. The distance of logistics transportation and the difficulty of transportation all lead to different costs, which in turn affect their price in the market.
Roughly speaking, in today's market conditions, the price of 4-hydroxypyridine-3-carboxyethyl ester of ordinary specifications may be around tens of yuan to hundreds of yuan per gram. However, this is only an approximate number, and the actual price should be based on real-time market conditions, the amount of purchase, and the quality of quality. If the purchase volume is quite large, or negotiate with the merchant, or you can get a suitable price. To determine the exact price, it is also necessary to consult the suppliers of chemical raw materials in detail to obtain an accurate figure.

The storage conditions of 4-aminopyridine-3-carboxylic acid ethyl ester vary depending on the characteristics of this substance.
4-aminopyridine-3-carboxylic acid ethyl ester, or more active, in contact with light, heat, moisture, etc., may be at risk of qualitative change. Therefore, it should be placed in a cool, dry and dark place. For those who are cool, it is said that the ambient temperature should not be too high, usually not more than 25 ° C. Excessive temperature may accelerate its chemical reaction and cause changes in its composition. A dry place can avoid moisture and damage its quality due to reactions such as moisture or hydrolysis. Avoidance from light is also important. Light radiation may cause photochemical reactions and change the chemical structure.
Furthermore, this substance may interact with other substances, so it should be stored separately, away from oxidants, acids, bases and other substances. If it coexists with oxidants, there may be a risk of oxidation; if it encounters acids or alkalis, it may cause chemical reactions, causing failure or harmful substances.
And the place of storage should be well ventilated to prevent the accumulation of harmful gases and affect its quality. After taking it, the container should be sealed to prevent it from excessive contact with air and deterioration. In this way, the purpose of properly storing 4-aminopyridine-3-ethyl carboxylate can be achieved to ensure its quality and stability.