4-aminopyridine-3-carboxamide

4-Aminopyridine-3-formamide has a wide range of uses. In the field of medicine, it is a key raw material for the development of new drugs. The structure of Gainpyridine and amide endows it with unique chemical properties and biological activities, which can play a role in targeting specific disease targets. Physicians use this to develop anti-arrhythmic drugs. This structure can act on the ion channel of myocardial cell membrane, regulate ion flow, and restore normal heart rhythm. It can also be used to create anti-tumor drugs, which can interfere with the growth and proliferation of tumor cells through their activity, adding a powerful weapon to the fight against cancer.
In the field of materials science, it also has extraordinary performance. It can be used as an important intermediate in the synthesis of functional materials. For example, when preparing materials with special optical and electrical properties, 4-aminopyridine-3-formamide participates in the reaction, which can precisely control the molecular structure of the material, so that it can obtain special properties such as fluorescence properties and electrical conductivity. Taking the synthesis of new organic optoelectronic materials as an example, its structure can optimize the charge transport efficiency of materials, improve the photoelectric conversion performance, and help the development of new display technologies and optoelectronic devices.
In the field of agricultural chemistry, it also has important value. Or it can develop new pesticides, use their chemical properties to target pests and pathogens, and develop efficient and low-toxicity insecticides and fungicides. It can specifically interfere with the nervous system of pests or the metabolic process of pathogens, effectively control pests and diseases, ensure crop yield and quality, and have a small impact on the environment, meeting the current needs of green agriculture development.

The synthesis method of 4-aminopyridine-3-formamide has been explored by many parties throughout the ages. One of the common methods is to use pyridine as the starting material. The carboxyl group is introduced at a specific position of the pyridine first, which can be achieved under appropriate reaction conditions with suitable carboxylation reagents. Then, the carboxyl group is amidated, the appropriate amination reagent is selected, and the reaction parameters, such as temperature, pH, and reaction time, are carefully adjusted, so that the carboxyl group can be smoothly converted into a formamide group.
There are also those who use nitrogen-containing heterocyclic compounds as the starting materials, and the target molecular structure is gradually constructed by means of ingenious reaction paths. For example, amino and formamide groups can be introduced by nucleophilic substitution of heterocycles with specific reagents. This process requires careful consideration of the reagent activity and the selectivity of the reaction check point to ensure that the reaction proceeds in the desired direction.
There are also those who use halogenated pyridine derivatives as starting materials. First, the halogen atom is replaced by an amino group through a nucleophilic substitution reaction, and then the formamide group is introduced at the ortho position through a reasonable reaction step. In this path, the activity of the halogen atom and the choice of the substitution reagent are all key factors affecting the success or failure of the reaction.
The synthesis method has its own advantages and disadvantages due to the difference of raw materials, the special reagents, and the change of conditions. It is necessary to weigh the advantages and disadvantages according to the actual situation, and make a careful choice to achieve the purpose of

4-Aminopyridine-3-formamide, the physical and chemical properties of this substance, have the following numbers.
Looking at its appearance, at room temperature, it is mostly white to white crystalline powder, delicate and uniform, like finely crushed Qiongyao, or shimmering with a slight luster under light.
When it comes to solubility, it can be slightly dissolved in water, just like fine sand entering water. Although it cannot completely disappear without a trace, it can also melt into a slightly turbid state; while in organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc., the solubility is quite good, just like salt entering boiling water, quickly melting, and the solution is clear. < Br >
Its melting point is also a key physical property. After determination, it is about a certain temperature range. When the temperature rises to this range, the substance gradually melts from solid to liquid, just like ice and snow in spring, quietly changing its shape. The characteristics of this melting point can be an important basis in the process of identification and purification, just like a sign of a dark night road.
Another word about its chemical properties, in the molecular structure, amino groups and formamide groups give it a certain reactivity. Amino groups are alkaline and can neutralize with acids, just like yin and yang, generating corresponding salt compounds. The formamide group is not idle, and can participate in a variety of organic reactions, such as meeting nucleophiles, or can cause wonderful changes such as substitution. In the field of organic synthesis, it is like a smart chess piece, participating in the construction of complex chemical structures.
The physicochemical properties of 4-aminopyridine-3-formamide have important significance and applications in chemical research, drug synthesis and many other fields, paving the way for the exploration of a more delicate chemical world.

The price of 4-aminopyridine-3-formamide in the market is difficult to determine. The price often changes for many reasons.
The first to bear the brunt is the purity. If the purity of this substance is extremely high, it is almost flawless, and the price is high; if the purity is slightly inferior and impurities are slightly stored, the price is slightly cheaper. For example, gold and jade, the higher the purity, the greater the value.
Furthermore, the supply and demand of the city also affect the price. If there are many people who want it, and the supply is small, it is like a rain in a drought, and the price will rise; on the contrary, if the supply exceeds the demand, it is like water overflowing the gully, and the price will decline.
The difficulty of production is also the main reason. If its preparation requires delicate methods, rare materials, and complicated processes, it requires a lot of manpower and material resources, and the price is not cheap; if it is easier to prepare, it requires only ordinary things and simple methods, and the price is close to the people.
In addition, the difference between sellers also makes the price different. Dajia Home, because of its reputation and rigorous quality control, sells at a high price; while small merchants' goods, or because the cost is slightly lower, the price is also slightly reduced.
The origin is different, and the price is also different. If this property in a certain real estate, due to the convenience of geographical location and rich resources, the cost is reduced and the price is low; other places need to be purchased and transported, and the freight is added, etc., the price will be high.
To sum up the above reasons, in order to determine the price of 4-aminopyridine-3-formamide in the market, it is necessary to carefully examine the purity, supply and demand, production difficulty, seller and origin, etc., to obtain a more accurate number, but it is ultimately difficult to hide.

4-Aminopyridine-3-formamide is a chemical substance. When using it, many safety precautions should be kept in mind.
Bear the brunt first, and protective equipment is essential. When touching this substance, it is advisable to wear appropriate protective clothing, which is essential to protect the body from damage. Protective gloves are also required to prevent skin contact with it. Because the substance may sensitize the skin, and once contaminated or penetrated, it is harmful to health. Eye protection is also crucial. Wearing goggles can prevent it from splashing into the eyes and damaging the eyes.
Furthermore, the operating environment needs to be paid special attention. It should be operated in a well-ventilated place, and if conditions permit, it is advisable to operate in a fume hood. This can allow volatile gas to be dispersed in time, avoid accumulation in the air, and reduce the risk of inhalation. Because of its volatile gas or irritation of the respiratory tract, or even, long-term inhalation may cause more serious health problems.
When storing, also pay attention to it. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties or the risk of combustion and explosion in case of open flames or hot topics. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed to prevent dangerous chemical reactions.
If accidentally contacted, emergency treatment must be prompt and appropriate. After skin contact, immediately remove contaminated clothing, rinse with plenty of flowing water for at least 15 minutes, and then seek medical attention. For eye contact, immediately lift the eyelids, rinse thoroughly with plenty of flowing water or normal saline for at least 15 minutes, and seek medical attention immediately. If you inhale accidentally, you should quickly leave the scene to a fresh place in the air to keep the respiratory tract unobstructed. If breathing difficulties, give oxygen; if breathing stops, immediately perform artificial respiration and seek medical attention. Those who eat by mistake should not induce vomiting. They should drink enough warm water and seek medical attention.
In short, in the operation and storage of 4-aminopyridine-3-formamide, it is necessary to strictly follow safety procedures, and must not be negligent, so as to ensure safety.