4-amino-3-pyridinecarboxylic acid methyl ester

4-Amino-3-methylpyridinecarboxylate, this is an organic compound. Its physical properties are quite important. Under normal temperature and pressure, it is mostly in a solid state, or in the form of white to light yellow crystalline powder. The appearance is more uniform and delicate, and it resembles a fine powder that is finely ground. Looking at its solubility, it shows certain solubility in common organic solvents, such as methanol, ethanol, dichloromethane, etc. In methanol, with a little stirring, it will slowly dissolve, just like snowflakes integrated into warm water, gradually disappearing, forming a uniform solution. This property is due to the interaction between its molecular structure and organic solvent molecules.
In terms of chemical properties, both amino and ester groups in this compound have active reactivity. The amino group is like a passionate dancer, easily reacts with acids to generate corresponding salts. When it meets hydrochloric acid, the two quickly combine, and the amino group accepts hydrogen ions, transforming into positively charged ammonium ions, just like the dancer grabs the sparkling dance partner and dances hand in hand to generate hydrochloride products. The ester group is like an elegant swordsman, capable of hydrolysis under alkaline conditions. Taking the sodium hydroxide solution as an example, the ester group is cut open by a precise blade and decomposed into the corresponding carboxylate and alcohol, just like the swordsman cleverly disassembles the opponent's moves in combat.
In addition, the pyridine ring in the 4-amino-3-pyridinecarboxylate molecule gives it a certain aromaticity and stability, like a strong castle, making the entire molecular structure relatively stable. Under some mild reaction conditions, it is not prone to unprovoked structural changes, which lays a solid foundation for its participation in various organic synthesis reactions, just like a solid foundation supporting tall buildings.

4-Amino-3-pyridinecarboxylate methyl ester has a wide range of uses. In the field of pharmaceutical and chemical industry, it is a key intermediate for the synthesis of many drugs. The unique structure of the gainpyridine ring and amino and ester groups endows the compounds with diverse reactivity and biological activity.
For example, in the development of antibacterial drugs, this base can be cleverly modified and derived to produce new drugs that have strong inhibitory and killing effects on specific bacteria. This structure can precisely act on the key targets of pathogens and interfere with their metabolism and reproduction process, just like good medicine, targeting the focus.
In the field of materials science, 4-amino-3-pyridinecarboxylate methyl ester also has potential value. Due to its nitrogen-containing heterocycles and reactive groups, it can participate in polymerization reactions to build polymer materials with specific properties. It can increase the stability and conductivity of the material, or give it the adsorption and separation properties of specific substances, like a skilled craftsman, to build a unique material structure.
In organic synthesis chemistry, it is an important starting material for the construction of complex organic molecules. Chemists use various organic reactions, such as nucleophilic substitution, coupling reactions, etc., as a basis, such as building exquisite pavilions, and gradually building complex and functional organic compounds, which add to the treasure house of organic synthesis.

The synthesis of 4-amino-3-pyridinecarboxylate methyl ester is an important topic in the field of organic synthesis. The synthesis method follows several common paths.
One of them can be started from 3-pyridinecarboxylate methyl ester. The compound is first modified with appropriate protecting groups to protect its carboxyl methyl ester part. Subsequently, amino groups are introduced through nucleophilic substitution reactions. Usually carried out under specific reaction conditions with suitable amination reagents. During the reaction, attention should be paid to the control of reaction temperature, time and reagent dosage. If the temperature is too high or side reactions occur, if it is too low, the reaction rate will be delayed. If the time is too short, the reaction will not be fully functional; if it is too long, there may be a risk of product decomposition. The dosage of the reagent must also be accurate, too much or cause the formation of impurities, and too little will cause the reaction to be incomplete.
Second, 4-halo-3-methylpyridinecarboxylate can also be used as a raw material. The activity of the halogen atom makes it easy to be substituted by the amino group. This substitution reaction may require the assistance of a catalyst to improve the reaction efficiency. The choice of catalyst depends on the characteristics of the reaction system and the type of halogen atom. The reaction environment is also critical. For example, the choice of solvent needs to consider its solubility to the reactants and products, as well as its impact on the reaction process. Polar solvents may be conducive to the progress of nucleophilic substitution reactions, while non-polar solvents may be suitable for specific reaction conditions.
Third, starting from the pyridine derivative, the target molecule is constructed through multi-step reaction. The pyridine ring is first functionalized with specific groups, such as the introduction of carboxyl methyl esters and halogen atoms, and then gradually converted into amino groups. Although there are many steps in this path, each step can be flexibly adjusted according to the purity and yield of the desired product.
Synthesis of 4-amino-3-pyridinecarboxylate methyl ester, each method has its own advantages and disadvantages. When synthesizing, it is necessary to comprehensively consider the cost of raw materials, the difficulty of controlling the reaction conditions, the purity and yield of the product, and many other factors before selecting the optimal synthesis path.

I am wondering about "4-amino-3-pyridinecarboxylic acid methyl ester", this is a chemical substance, or 4-amino-3-pyridinecarboxylic acid methyl ester in Chinese. As for its market price, it is difficult to determine.
Because the price of chemical substances is often affected by many factors. First, the price of raw materials. If the raw materials for preparing this substance are rare and expensive, or if it is difficult to obtain and requires complicated processes, the price of this substance will be high. Second, the production process is simple and simple. If the preparation process is fine, high-tech and precision instruments are required, and the reaction conditions are demanding, it requires a lot of manpower, material resources and time, and the cost will be high, and the price will also rise. Third, the market supply and demand situation. If the market demand for this material is strong, but the supply is scarce, according to the reason of supply and demand, the price will rise; conversely, if the supply exceeds demand, the price will drop. Fourth, purity requirements. High-purity products are difficult to prepare, expensive, and the price is much higher than that of ordinary purity.
In addition, different suppliers, purchase quantities, regional differences, etc., will cause their prices to vary. In general, in the professional chemical reagent market, the price of small packages and high purity may be relatively high; if you buy in large quantities, you can negotiate with suppliers or get preferential prices. However, to know the exact market price, you need to consult the chemical reagent supplier in detail, or search on the relevant chemical product trading platform to get a more accurate price.

4-Amino-3-pyridinecarboxylic acid methyl ester, many matters need to be paid attention to during storage and transportation.
This compound may have an impact on the environment. When storing, find a dry, cool and well-ventilated place, away from fire and heat sources, to prevent danger caused by thermal decomposition. It should be stored separately from oxidants, acids, alkalis, etc., and must not be stored in combination. If it comes into contact with it or reacts chemically, it will endanger safety.
Packaging must be tight to ensure that there is no risk of leakage. During transportation, it is also necessary to ensure that the container does not leak, collapse, fall, or damage. Transportation vehicles should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. Summer transportation should be selected in the morning and evening to avoid high temperature and sun. During transportation, it should be protected from exposure to the sun, rain and high temperature.
When loading and unloading, it should be handled lightly, so as not to damage the container and cause material leakage. Operators are in front of suitable protective equipment. If they accidentally come into contact, they should be handled according to corresponding emergency rescue measures. All of these are to ensure the safety of 4-amino-3-pyridyl carboxylate methyl ester during storage and transportation, avoid accidents, and protect people and the environment.