4 Amino 3 Methoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

4-Amino-3-methoxypyridine

    Specifications

    HS Code

    116823

    Name 4-Amino-3-methoxypyridine
    Molecular Formula C6H8N2O
    Molecular Weight 124.14 g/mol
    Appearance White to off - white solid
    Cas Number 14526-27-7
    Melting Point 93 - 95 °C
    Boiling Point 276.3 °C at 760 mmHg
    Density 1.186 g/cm³
    Solubility In Water Slightly soluble
    Pka 4.76
    Flash Point 120.9 °C

    As an accredited 4-Amino-3-methoxypyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 4-Amino-3-methoxypyridine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 4-Amino-3-methoxypyridine in China?
    As a trusted 4-Amino-3-methoxypyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Amino-3-methoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Amino-3-methoxypyridine?
    4-Amino-3-methoxypyridine, which has a wide range of uses. In the field of medicine, it is a key intermediate in organic synthesis. Because it contains a special nitrogen heterocyclic structure and active groups such as amino and methoxy groups, it can participate in the construction of many drug molecules. For example, it can be spliced with other compounds through specific chemical reactions to prepare drugs for the treatment of specific diseases, such as in the development of anti-arrhythmic drugs, or play an important role in the development of anti-arrhythmia drugs, or through precise chemical modification, giving drugs better pharmacological activity and pharmacokinetic properties.
    In the field of materials science, it also has important uses. It can be used to prepare functional materials, such as organic optoelectronic materials. Due to its unique photoelectric properties, through rational design and synthesis, materials that respond well to light and electrical signals can be prepared, or applied to organic Light Emitting Diode (OLED), solar cells and other devices to help improve the photoelectric conversion efficiency and stability of the device.
    In the field of pesticides, 4-amino-3-methoxy pyridine is also useful. As a raw material for the synthesis of new pesticides, by reacting with other chemical substances, pesticide varieties with high insecticidal, bactericidal or herbicidal activities can be created. Due to its unique chemical structure, pesticides may be highly selective and low environmentally toxic to specific target organisms, meeting the needs of modern green pesticide development.
    In summary, 4-amino-3-methoxypyridine is an indispensable and important compound in many fields such as medicine, materials science, and pesticides. With the continuous progress of science and technology, its application prospects will also be broader.
    What are the physical properties of 4-Amino-3-methoxypyridine?
    4-Amino-3-methoxypyridine is one of the organic compounds. It has many physical properties and is related to the chemical and pharmaceutical fields.
    First of all, its appearance is mostly white to light yellow crystalline powder under normal temperature and pressure. It looks fine and has a uniform texture. This color state is easy to identify with the naked eye. In related production and experimental processes, it provides an intuitive basis for distinguishing its purity and state.
    Second described melting point, its melting point is about 95-99 ° C. The melting point is an important physical property of the substance. This temperature range indicates that it will change from solid state to liquid state at a specific stage when heated. This property is of great significance in purification, separation and quality inspection. The purity can be determined by means of melting point determination. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point decreases and the range becomes wider.
    Furthermore, when it comes to solubility, 4-amino-3-methoxypyridine is slightly soluble in water. This is because water is a polar solvent, and although there are amino and methoxy groups in the structure of the compound that can form hydrogen bonds with water, the hydrophobicity of the pyridine ring has a greater impact, resulting in weak interaction with water as a whole. However, its solubility in organic solvents such as ethanol and chloroform is good. This solubility characteristic plays an extraordinary role in organic synthesis, and the synthesis reaction often requires a suitable solvent to dissolve the reactants to facilitate intermolecular collisions and reactions. The use of organic solvents such as ethanol can promote the uniform dispersion of the compound and improve the reaction efficiency and yield.
    In addition, it also has a certain stability. Under conventional conditions, if it does not encounter special chemical reagents such as strong oxidizing agents and strong acids and bases, its chemical structure is not easy to change. This stability makes storage and transportation more convenient and reduces the risk of deterioration. However, in special environments or reaction systems, the activity check points of its amino and methoxy groups can react, participate in various organic synthesis paths, and derive a variety of compounds with different functions and uses.
    What are 4-Amino-3-methoxypyridine synthesis methods?
    The method of synthesizing 4-amino-3-methoxypyridine is described in many ancient books. The first method is to use 3-methoxypyridine as the starting material and through nitrification to obtain 3-methoxy-4-nitropyridine. In this step, sulfuric acid and nitric acid are mixed to form a mixed acid, and temperature control is added dropwise to 3-methoxypyridine, and the reaction is stirred. After nitrification to amino with a reducing agent, such as iron and hydrochloric acid, or hydrogen and palladium carbon, 4-amino-3-methoxypyridine is obtained. < Br >
    Both can also be 3-methoxy-4-halogenated pyridine as raw material. Halogenated, such as chlorine, bromine, etc. The halogenated compound is heated with ammonia or amine compounds in suitable solvents, such as ethanol, dimethylformamide, etc., catalyzed by adding bases, such as potassium carbonate, sodium hydroxide, etc. The halogen atom is replaced by an amino group to obtain 4-amino-3-methoxy pyridine.
    All three, or can be obtained by rearrangement of pyridine derivatives. The structure of 4-amino-3-methoxypyridine is constructed by intramolecular rearrangement of specific substituted pyridine derivatives under suitable catalyst and reaction conditions. The catalysts used may be metal salts or organic bases, and the reaction conditions need to be carefully controlled. Factors such as temperature, time, solvent, etc. are all related to the yield and purity of the product.
    All synthesis methods have advantages and disadvantages. The purpose of synthesis can only be achieved by careful selection according to the availability of raw materials, cost considerations, the complexity and simplicity of the process, and the requirements for product purity and yield.
    4-Amino-3-methoxypyridine What are the precautions during storage and transportation?
    4-Amino-3-methoxypyridine is also an organic compound. When storing and transporting, it is necessary to pay attention to many matters to ensure its quality and safety.
    First words storage. This compound should be placed in a cool, dry and well-ventilated place. Because of the cool environment, it can be avoided from decomposition or deterioration due to excessive temperature. If it is in a high temperature environment, its chemical structure may be affected, resulting in changes in its properties, and it is difficult to achieve the desired effect in subsequent use. The dry place is also the key. It may be hygroscopic. If the moisture is too heavy, it is easy to absorb water and deliquescence, which not only affects the purity, but also may initiate chemical reactions. Good ventilation can disperse harmful gases that may evaporate in time and ensure the safety of the storage space.
    Furthermore, it should be stored separately from oxidants, acids and other substances. This is due to the chemical properties of 4-amino-3-methoxy pyridine, which makes it come into contact with oxidants, or triggers violent oxidation reactions, and even causes dangers such as combustion and explosion. Coexisting with acids, or chemical reactions may occur, causing compounds to fail and harmful gases may be generated.
    As for transportation, caution is also required. The transportation container must be strong and well sealed. Strong equipment can prevent damage due to collision and vibration during transportation, causing compound leakage. Good sealing can avoid contact with outside air, moisture, etc. When loading and unloading, the operation should be gentle, and do not load and unload brutally, so as not to damage the container. During transportation, it is also necessary to prevent exposure to the sun and rain. If exposed to the hot sun, the temperature will rise sharply, or the compound will be unstable; in case of rain, it will be susceptible to moisture and damage its quality.
    In short, when storing and transporting 4-amino-3-methoxypyridine, it is necessary to follow relevant specifications according to its chemical properties, and be careful to ensure its safety and quality.
    What is the market outlook for 4-Amino-3-methoxypyridine?
    4-Amino-3-methoxypyridine is a crucial chemical raw material in the field of organic synthesis. Looking at its market prospects, it is indeed quite broad, and it shows significant application potential in many fields.
    In the field of medicinal chemistry, this compound can be said to shine. Due to its unique chemical structure, it can be used as a key intermediate for the synthesis of a variety of biologically active drug molecules. Taking cardiovascular disease treatment drugs as an example, 4-amino-3-methoxypyridine can participate in the construction of drugs with functions such as regulating blood pressure and improving cardiac function after ingenious chemical modification and transformation. Furthermore, in the research and development of anti-tumor drugs, it can also serve as a core building block, providing the possibility for the creation of new anti-cancer drugs. With the increasing aging of the global population and the increasing incidence of various diseases, the demand for high-efficiency and specific drugs in the pharmaceutical industry continues to rise. As a result, 4-amino-3-methoxypyridine, an important raw material for drug synthesis, is bound to rise in market demand.
    In the field of materials science, 4-amino-3-methoxypyridine has also emerged. With its special electronic structure and reactivity, it can be applied to the preparation of high-performance organic optoelectronic materials. Such as organic Light Emitting Diode (OLED), this compound can be used as a functional dopant to optimize the luminous efficiency and stability of OLED devices. With the rapid development of display technology, OLED screens are widely used in various display devices such as smartphones and TVs due to their excellent properties such as self-emission, high contrast, and wide viewing angle. Therefore, the surge in demand for related high-performance organic optoelectronic materials has opened up a broad market space for 4-amino-3-methoxypyridine.
    In the field of agricultural chemistry, 4-amino-3-methoxypyridine also plays an indispensable role. It can be used as an important starting material for the synthesis of new pesticides. Through rational molecular design and synthesis route optimization, pesticide products with high insecticidal and bactericidal activities and environmental friendliness can be prepared. In today's era of emphasizing the quality, safety and environmental protection of agricultural products, such new pesticides are favored by the market. With the acceleration of agricultural modernization, the demand for green and efficient pesticides is increasing, which undoubtedly injects a strong market driving force for the application of 4-amino-3-methoxypyridine in the field of agricultural chemistry.
    To sum up, 4-amino-3-methoxypyridine has a bright market prospect due to its wide application in medicine, materials, agriculture and other fields, and is expected to usher in more considerable market growth in the vigorous development of related industries in the future.